Our mission is to save lives and improve health outcomes by enabling the government and private sector to strengthen and sustain quality health systems.

Joined December 2010
TB prevention options growing from what is available today to new TPT regimens, long-acting injectables, and novel vaccines. Our new toolkit compares them all: ow.ly/AP7z50ZYuoa #TBPrevention @GlobalFund @WHO @gatesfoundation @gavi
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Could AI allow health systems in LMICs leapfrog legacy systems in wealthier countries? CEO @NeilBuddyShah on how ministries of health can flip the script: ow.ly/9gIH50ZZpJu
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AI can put expert-level ultrasound reads in the hands of frontline health workers. CEO @NeilBuddyShah on what it will take to price, regulate, and scale tools like this: ow.ly/afcX50ZZpyM
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Several new TB prevention tools are in trials. But children aged 5-14 in the general population aren’t covered by any of them. Our new toolkit lays out who the pipeline could reach, and where gaps remain. ow.ly/JtWJ50ZYuoU @GlobalFund @WHO @gatesfoundation @gavi
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"There are large amounts of capital coming in to solve some of the most important problems in the world." Our CEO @NeilBuddyShah in @nytimes on how new AI-era philanthropy could reshape global health, and why health systems have to be part of the answer: ow.ly/O6gw50ZZs3l
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What’s on the horizon for TB prevention? Our new toolkit puts today’s options and the pipeline of new pharmaceutical prevention options side by side. ow.ly/nvvG50ZYu8k #TBPrevention @GlobalFund @WHO @gatesfoundation @gavi
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CHAI has helped negotiate more than 140 deals that lowered prices of life-saving medicines and diagnostics. Why do they work? CEO @NeilBuddyShah explains on @MedAccessUK's new podcast: ow.ly/iUzR50ZZ5Zu
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It’s #ILPPW: 1 in 3 children worldwide have blood lead levels above @WHO threshold, yet testing is out of reach in many countries. Join CHAI & @RenPhilanthropy on Oct 29, 10am EDT to discuss low-cost testing & an open call for innovators. @VitalStrat @UW ow.ly/hxfX50ZYZ0h
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"Before I could not thread the needle in my sewing machine, but now I can do it very well." Maryam Yakub, a tailor for more than 13 years, got free reading glasses through Nigeria's Jigi Bola 2.0, which reached 1.3 million people in year one. #WorldSightDay
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Join us Oct 8 for a virtual Innovator Showcase on LLM-enabled clinical decision support, hosted by the AI Commons for Global Health, which we co-launched with Endless Health (@rubayatkhan) and @AgencyFund. 8am ET | 3pm EAT | 5:30pm IST Register: ow.ly/4nIP50ZUFji
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38% -> nearly 100% across 50+ districts. In Uganda, almost every child who needs oxygen now gets it. The fix started with a simple idea: swap empty cylinders for full ones at delivery. #WorldOxygenDay #InvestInOxygen @MinofHealthUG | @gatesfoundation
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A year ago, we announced a deal to bring lenacapavir, a twice-yearly HIV prevention shot, to 120 LMICs for US$40. Now the focus is delivery. CHAI CEO Buddy Shah joined @AlterIgoe on @devex Theory of Change at #UNGA81. ow.ly/34K650ZTF94 @drreddys | @UNITAID | @WitsRHI
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This week Papua New Guinea launched HPV vaccinations nationally, reaching an estimated 60,000 girls aged 9–14 in its first phase—protecting women against cervical cancer, the country's leading cause of cancer deaths. Proud to support the Government of PNG, @gavi @WHO, @UNICEF
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New: seven years of evidence on what it takes to get new and underused SRH products to the women who need them in low- and middle-income countries. Read the paper: ow.ly/Jume50ZKY6e @gatesfoundation @FCDOGovUK @CIFFchild @MSDInvents #MSDforMothers
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Last week CHAI & Freddie launched PrEP ONWARDS—every new PrEP start at Freddie funds a dose of lenacapavir for someone in Africa. Less than 1 in 4 who could benefit from PrEP have access to it today; this is one way we're working to close that gap, faster. ow.ly/GhlR50ZyE28
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A million more children. Zero new donor dollars. CHAI's agreement with Vista Fortifoods cuts the price of life-saving malnutrition treatment by 30% to US$32.50/box for RUTF, the lowest available today. ow.ly/Ksut50ZyCeF
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CHAI retweeted
For children living with HIV, treatment needs to work for them. Child-friendly medicines are helping make care simpler for children, families and health workers. Awa’s story shows why putting people at the centre of innovation matters. @MedsPatentPool
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🔴 LIVE at #AIDS2026: Early results from #Zambia's phased lenacapavir rollout. One of the first real-world looks at programmatic outcomes as LEN moves from pilot to scale. #Lenacapavir @iasociety @mohzambia
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🔴 LIVE at #AIDS2026, Room 103: As US and Global Fund support shrinks, governments aren't waiting. Sierra Leone, Malawi, Cambodia & Zimbabwe share real strategies for sustaining HIV programs on their own terms. @iasociety @mohs_sl @health_malawi @MoHCCZim #Cambodia
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Malawi is rewriting its HIV treatment guidelines for greater efficiency — from differentiated ART dispensing to expanded point-of-care viral load testing. At #AIDS2026, Dr. Stephen Macheso shares how evidence is shaping the country's next chapter of sustainable HIV care.
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Closing out our #AIDS2026's sustainability session: Gerald Nyamutamba on Zimbabwe integrating HIV, TB, and malaria supply chains under one government-led system with a multi-stakeholder technical working group driving coordination, transparency, and real cost savings.
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