@kath_lab

Professor @UniCologne Organic Chemistry, Chemical Biology, Nucleic Acids

 Köln, Deutschland
kathlab.uni-koeln.de
Joined March 2019
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  • Followers1K
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Happy to share our recent paper in @J_A_C_S! A de novo designed unnatural base pair that exploits halogen bonding as a directional interaction in DNA. We establish halogen bonding as a pairing force for genetic alphabet expansion. 🧬 ⚗️ @UniCologne @ChemUniCologne @BreugstLab
J. Am. Chem. Soc.@J_A_C_SFeb 13
Investigating Halogen Bonds as Pairing Force in an Artificial DNA Base Pair | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/jac…

Investigating Halogen Bonds as Pairing Force in an Artificial DNA Base Pair

Abstract. The past decades have seen significant expansion of the nucleic acid space with the development of modified artificial base pairs based on natura

pubs.acs.org
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Season’s greetings from @kath_lab! 🎄✨ Grateful for a year of great science 🧪📄, strong teamwork 🤝, and shared moments 🚢🎉 - and excited for what lies ahead 🚀 @ChemUniCologne @UniCologne
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Honored to share some big news: I’m now tenured as a W3 Professor of Organic Chemistry @UniCologne! Immensely grateful to all the group members who contributed to this journey🙏 — this milestone is ours to share. @ChemUniCologne #OrganicChemistry #Tenure 🍾🎉🧪🧬
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Stephanie Kath-Schorr retweeted
Wilhelmsson Lab@WilhelmssonLab22 Aug 2025
Accepted article published online today. Great work by Pauline Pfeiffer and the rest of the team! Here we follow nucleotides and cellular RNA inside live cells by metabolic labelling and FLIM. pubs.rsc.org/en/Content/Arti…

Monitoring nucleoside metabolism in living cells with a nucleobase analogue via fluorescence...

To overcome challenges in fluorescence labelling of RNA inside living cells we have recently introduced a direct approach using the fluorescent nucleobase

pubs.rsc.org
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Stephanie Kath-Schorr retweeted
Byron Purse@ByronPurse11 Jul 2025
I'm thrilled to share that Christian Ducho of @ducholab and I have been elected co-vice chairs of the @GordonConf on Nucleosides, Nucleotides and Oligonucleotides for 2027 and we'll be co-chairs in 2029! Thanks to the community for choosing us to lead this truly great meeting!
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🧬 New paper out in @ChemCommun by Robert Dörrenhaus and Philip Wagner @kath_lab! We introduce CTPT3, a stable C-nucleoside forming a hydrophobic base pair with dNaM for enabling enzymatic incorporation into DNA and RNA. @ChemUniCologne pubs.rsc.org/en/content/arti…

Towards a hydrolysis stable artificial base pair with C-glycosides†

Artificial base-pairs expand the genetic alphabet and allow for site-specific labeling, for example with fluorophores or spin labels, thereby enhancing the

pubs.rsc.org
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The legendary conference dinner! #SNAC2025 🥂🧬
Michal Hocek 🇨🇿 🇪🇺 🌍 🍷🧬🧪@hocekm11 Jun 2025
19SCNAC conference dinner
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Enjoying a fantastic week of nucleic acid chemistry 🧬⚗️🎉
Michal Hocek 🇨🇿 🇪🇺 🌍 🍷🧬🧪@hocekm10 Jun 2025
Participants of the 19SCNAC conference scnac.com/
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Celebrating 75 years of #FCI @chemieverband ! 🎉 Grateful for the funding that supports the research of @kath_lab including @JulianStrippel and Matea Rabar. @ChemUniCologne 🧬⚗️
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🧬🔬New paper online: Nucleic acid sensing using DNA-functionalized whispering gallery mode microlasers! Great collaboration with @TheGatherLab @sorayacaixeiro @SchubertLab @ChemUniCologne 🧪 #DNASensing #microlasers Nano Letters pubs.acs.org/doi/full/10.102…

DNA Sensing with Whispering Gallery Mode Microlasers

Abstract. Nucleic acid sensing is crucial for advancing diagnostics, therapeutic monitoring, and molecular biology research by enabling the precise identif

pubs.acs.org
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Grateful for this wonderful group of lab members @kath_lab @UniCologne! Happy holidays and Merry Christmas! 🎄🕯️🧬
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JOB ALERT! Two open PhD positions @kath_lab in the framework of the MSCA doctoral network MeChaNiSM! Searching for an organic chemist dedicated on nucleic acid chemistry. 🚀🎉🧬⚗️ More information here: kathlab.uni-koeln.de/en/job-… #organicchemistry #nucleicacids
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Please join us tomorrow for this year's Emanuel-Vogel-Lecture by Prof. Dr. Rainer Herges @kieluni #OrganicChemistry 🚀⚗️🎉
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Stephanie Kath-Schorr retweeted
TIDE (RTG 2591)@TIDE_rtg29 Nov 2024
We had the first retreat with the #PhDstudents of the 2nd cohort this week! The whole TIDE group went to Bad Neuenahr-Ahrweiler for 3 days. Besides discussing all the exciting new #research activities, there was also time for a tour of the Government Bunker and for socializing.
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Back from an exciting visit to Gothenburg @chalmersuniv discussing projects with Marcus @WilhelmssonLab and Fredrik @FWesterlund. Stay tuned for our PhD position offers in the MSCA doctoral network MeChaNiSM! 🎉🧬chalmers.se/en/projects/mech… #nucleicacids #chemicalbiology
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chalmers.se/en/projects/mech…

MeChaNiSM

Mechanical Characterization of Nucleic acids using Single Molecule techniques

chalmers.se
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Interesting talk by Ralf Strasser @Ralf_DBS at #GDChBioChem2024. He talked about their biophysical methods to study small molecule protein interactions. Cool application to reverse transcription with @kath_lab and molecular glues with @alessiociulli. pubs.rsc.org/en/content/arti…
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Stephanie Kath-Schorr retweeted
Steven Banik@StevenMBanik18 Sep 2024
Excited our final version of @tineisadora's work on targeted protein relocalization is out today @nature! Molecular control over protein localization could offer new opportunities for therapeutics and biological discovery. @Stanford_ChEMH @StanfordUChem nature.com/articles/s41586-0…

Targeted protein relocalization via protein transport coupling

Nature - Targeted protein relocalization using shuttle proteins with potent ligands amenable to incorporation into targeted relocalization activating molecules could be used to regulate cellular...

nature.com
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Kurt Alder Lecturer 2024 @ChemUniCologne Prof. Dr. Tanja Weil @WeilTanja @mpi_polymer gave us fantastic insights into controlling structure formation in cells!🚀🧫🧪⚗️ (📷:David van Gerven) Huge congrats also to our Kurt Alder prize winners! #OrganicChemistry
The winners of the Kurt Alder prize for the best PhDs of the year together with Gisela Kind and Stephanie Kath-Schorr @Kath_lab: Christina Wartmann, Lars Hemmersbach, Hannah Depmeier and Seyma Bozkus!

ALT The winners of the Kurt Alder prize for the best PhDs of the year together with Gisela Kind and Stephanie Kath-Schorr @Kath_lab: Christina Wartmann, Lars Hemmersbach, Hannah Depmeier and Seyma Bozkus!

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Great @GDCh_aktuell lecture by Prof. Thomas Carell @ChemUniCologne about the origin of molecules and life on the early earth as well as teaching our students the basics of nucleic acid conformation! #nucleicacid #originoflife 🧬⚗️🧫🧪 @CarellThomas @CarellGroupLMU
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