AJP-Endocrinology and Metabolism

A large and talented team from @UTHealthBarshop @uthealthbarshop.bsky.social bring you today's paper, Low-frequency ultrasound reverses insulin resistance and diabetes-induced changes in the muscle transcriptome in aged mice (Erik Marchant et al.): ow.ly/7TcU5101tgf

Research Article by J Du et al. #Exercise-mimicking effect of #exogenouslactate administration: promoting #visceralfat reduction via #ventromedial #hypothalamic SF-1 #neurons in female rats ow.ly/5ZYy5100t66

From our Translational Physiology collection comes, L-type calcium channel blockade worsens #glucose tolerance and β-cell function in C57BL6/J mice exposed to intermittent #hypoxia (Stanley Chen Cardenas et al. @EndoHopkins @umiamimedicine): ow.ly/Ivtw5100eEm

Today's article is especially helpful for high-risk #T2D populations, Impact of the trans-ancestry polygenic risk score on type 2 #diabetes risk, onset age and progression among population in Taiwan (Shi-Heng Wang et al.): ow.ly/qrSi50ZY98U

An equally large and talented team from University of New South Wales Sydney put together today's spotlight piece, Oocyte and cumulus cell cooperativity and metabolic plasticity under the direction of #oocyte #paracrine factors (Dulama Richani et al.): ow.ly/xm9v50ZXkyY

Research Article by AR Quirk et al. Females with #normalweightobesity display evidence of #postprandial #dyslipidemia and #basalintestinalpermeability ow.ly/aj9n50ZVwEc

You only need a moment to check out today's Short Report in Immunometabolism, Bruton’s tyrosine kinase (BTK) inhibitors alter blood #glucose and insulin in #obese mice but reduce inflammation independent of #BTK (Darryl Chan et al. @MacMODR): ow.ly/rAiF50ZU4H4

👉 This new Call for Papers explores the intricate interplay among the nervous, immune, endocrine and metabolic systems, revealing these networks as a dynamic regulatory system rather than isolated physiological domains. Learn more at ow.ly/7PlR50ZUVtf.

This afternoon take a moment to review today's APS select article, Time-restricted #feeding reveals a role for neural #respiratory clocks in optimizing daily #ventilatory-metabolic coupling in mice (Aaron Jones et al. @MarquetteBioSci): ow.ly/V3O650ZU4Bn

Research Article by M Hirlemann et al. Additive effects of metformin on glucose homeostasis after metabolic-bariatric surgery in nonobese insulin-deficient diabetic rats ow.ly/aB4050ZR8il

Research Article by R Retnakaran et al. (@beaudrj) #Glucose-lowering in #type2 #diabetes may be mediated by improved proinsulin processing without better β-cell compensation ow.ly/v9Cc50ZR8f4

From our #Exercise Metabolism collection comes today's spotlight piece, The #mitochondrial lactate oxidation complex: endpoint for carbohydrate carbon disposal (Robert Leija et al.): ow.ly/CUyv50ZTHPS

Research Article by K Prins et al. (@Jenny_A_Visser) Enhanced behavioral responses to #ghrelin administration are unaffected by ghrelin deficiency in a DHT-induced #PCOS mouse model ow.ly/sHVg50ZR8c5

Today's article comes from a talented team at @TallinnTech from Estonia! Higher AMPK activation in mouse oxidative compared with #glycolytic #muscle does not correlate with LKB1 or CaMKKβ expression (Romani Bernasconi et al.): ow.ly/PyY750ZSNEP

Methods and Resources by DE Vieira et al. A noninvasive 13C-mannitol breath test to monitor #semaglutide treatment-induced delayed oral-cecal transit in mice ow.ly/ksqk50ZPakN

Research Article by AS Sherman et al. (@DrChung_Pendo) Validation in adult Black and White women of the ISS model for estimating #insulinsensitivity and beta-cell function from mixed-meal tests ow.ly/CPju50ZPahb

Take a moment to review today's Short Report spotlight paper, Intermittent fasting increases fat #oxidation and promotes metabolic flexibility in lean mice but not #obese type 2 #diabetic mice (Meghan Conn et al. @McMasterU): ow.ly/pQCx50ZR82p

Research Article by SR Heaselgrave et al. Adipocyte β3-adrenergic receptor signaling attenuates #leptinproduction but is dispensable for fasting induced #leptinsuppression ow.ly/HXM750ZPacQ

An equally large and talented team from @UCPH_Research put together today's paper in our Clinical Metabolism collection, Effect of ghrelin on #glucose tolerance, gut #hormones, #appetite, and food intake after sleeve #gastrectomy (Nora Hedbäck et al.): ow.ly/paWQ50ZQjWM

Review by GU Ortiz et al. Mechanistic drivers of thermogenic #adiposetissue dysfunction in #aging and #obesity ow.ly/UGG750ZMF4C