Marom Bikson (@MaromBikson) header
Marom Bikson (@MaromBikson) profile picture

Biomedical engineer and scientist. Interested in medical devices that translate scientific innovation to patients - design, testing, regulatory, deployment...

New York
Joined March 2011
"Wearable disposable electrotherapy" @NatureComms A new class of non-invasive electrical stimulation used like a band-aid. Stick on a mm-thick patch & a single \ dose delivered. No electronics=environmentally benign. Scalable manufacture=pennies per device nature.com/articles/s41467-0…
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This talk 👆also addresses the contrast between significant dose 'acceleration' with TMS, and dose paralysis with tDCS.
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Thank you European Society for Brain Stimulation (ESBS) for a great event.
Looking forward to speaking Oct 17th at the 7th European Conference on Brain Stimulation (Naples) on "What was once impossible: How better electrode technology transforms outcome" slides: static1.squarespace.com/stat…
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Looking forward to speaking Oct 17th at the 7th European Conference on Brain Stimulation (Naples) on "What was once impossible: How better electrode technology transforms outcome" slides: static1.squarespace.com/stat…
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I like this series of photos of me (credit the 7th BEM Summit) : the different reactions we have while listening to a scientific talks!
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Now open access on PMC: Niranjan Khadka Boshuo Wang “Role of frequency-dependent and capacitive tissue properties in spinal cord stimulation models” pmc.ncbi.nlm.nih.gov/article… For folks working on SCS modeling, we asks: When is the standard quasi-static approximation good enough"?
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Takeaways: - We tested the impact of frequency-dependent tissue conductivity (dispersion) and tissue capacitance/permittivity on predicted SCS electric fields across a broad frequency range. - The effect of tissue capacitance was minimal for the conditions tested. ...
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PMC (free full text) version of “A Brief History of Slow Spinal Potentials, Gate Theory of Pain, and Spinal Cord Stimulation” Melzack & Wall’s gate theory of pain endures for 6decades, directly invention of SCS & driving ongoing innovation.... 👇
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pmc.ncbi.nlm.nih.gov/article… ...Melzack was a neurophysiologist; the gate manifest as a slow potential - an evoked signal detected consistently across classical preclinical and human studies. Can modern SCS re-discover the "pain gate signal"?
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A great discussion with Matteo Cucchi @BioelDrop We start general but go deep. 1) How do we advance brain stimulation treatments without complete (or correct) mechanisms? 👇
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youtube.com/watch?v=NMxItk2V… 2) How do we target brain regions: invasive, non-invasive superficial (TMS, HD-tDCS), and non-invasive deep (such as Temporal Interference). 3) What is the relationship between endogenous electric fields and low-intensity brain stimulation?
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Our new systematic review and meta-analysis is available online: Long-Term Pain Reduction and Explantation Rates of Spinal Cord Stimulation Summary: 3 years after permanent SCS implantation, an estimated 44.7% of patients undergone explantation or reported < 50% pain reduction 👇
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Neuromodulation: Technology at the Neural Interface (preprint): sciencedirect.com/science/ar…
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This PCLC guidance was needed to clarify the application to neuromodulation of the 2023 FDA “Technical Considerations for Medical Devices with Physiologic Closed-Loop Control Technology,” which references the International Electrotechnical Commission (IEC) 60601-1-10 requirements
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Our new paper on dose–response in neuromodulation is now out in the Brain Stimulation Journal: sciencedirect.com/science/ar… #Neuromodulation #BrainStimulation #DoseResponse #NonInvasiveBrainStimulation #tES #TMS #ECT #tFUS
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Researchers from different backgrounds came together, bringing their perspective on what “dose” &“response” mean. Through these discussions we saw: though we all study dose–response, we often speak slightly different “languages.” This paper is the result of those conversations.
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Why are drug therapies so ubiquitous compared to brain stimulation? We argue in the American Journal of Psychiatry that the relatively limited use of brain stimulation in current psychiatric practice (especially as a first-line therapy) compared to pharmacotherapy is driven by..
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New youtube lecture: How do non-invasive electrical stimulation electrodes work? Across all applications (from TENS to tDCS), all non-invasive electrodes have 2 parts: a metal part & the salty part. This talk explains why & how the parts are configured. youtu.be/40Dd36h8KL0?si=-23e…
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new publication: Electrophysiologic Characteristics of Epidural Spinal Signals in Preclinical Models of Spinal Cord Stimulation. eCAPs, ESAPs, EMGs, artifacts, and more.. sciencedirect.com/science/ar…
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Final open-access "Low intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines (2017–2025: An update) – endorsed by the European Society for Brain Stimulation (ESBS) and IFCN" sciencedirect.com/science/ar…
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It was my special privilege to award the #NANS2026 award to Dr. Cameron McIntyre. Who has helped shape the entire field of computer-driven neuromodulation design (including volume of tissue activated and "sweet spots") and model-personalized brain stimulation...
A big congrats to Dr. Cameron McIntyre, inaugural recipient of the Distinguished Service in Science & Technology Award—a well-deserved honor for his incredible work 🏆 #NANS2026 @MaromBikson
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...(including connectomic stimulation). As I said in my opening remarks, I have know Cameron since we were graduate students together at Case, taking the neural engineering class. Now I teach that class and use Cameron's paper.
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