Ayana April-Sanders, PhD (@AApril_Sanders) profile picture

Cardiovascular disease and social epidemiologist | Instructor @RutgersSPH |

NJ
Joined April 2020
Huge congratulations to @PriscillaDuranL on presenting her research and receiving the Award for Excellence in Research Addressing Cardiovascular Health Equity at #EpiLifestyle26 👏🏽 Well deserved recognition! Outstanding sessions this year—already looking forward to 2027!
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Now in the Oral Abstract Session: Women’s & Maternal Health at #EpiLifestyle26 🧵 Covering cutting-edge work on gene–diet interactions, reproductive health, and cardiometabolic risk across the life course. Follow along for key insights 👇 @AHAScience
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Gestational weight & long-term CV health In Project Viva, higher postpartum weight retention (PPWR)—not gestational weight gain—was linked to worse mid-life cardiometabolic health. Focus may need to shift from pregnancy weight gain → sustained postpartum weight trajectories.
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Big takeaway from the Women’s & Maternal Health session at #EpiLifestyle26: Cardiovascular risk in women is shaped long before midlife—across genetics, reproductive history, pregnancy, and postpartum health. A life-course approach to prevention is essential. @AHAScience
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Adverse pregnancy outcomes (APOs) & later CV risk APOs were linked to: • Higher BP response during submaximal exercise • Shorter exercise duration Suggesting early vascular dysfunction and reduced fitness. #EpiLifestyle26 @AHAScience
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Endometriosis & CVD risk In UK Biobank data, women with endometriosis had a ~19% higher risk of cardiovascular disease. Highlights the need to consider endometriosis as more than a gynecologic condition. #EpiLifestyle26 @AHAScience
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🔍 What may explain this link? Findings suggest part of the association may be mediated by hysterectomy (± oophorectomy). Raises important questions about: • Disease severity • Treatment pathways • Long-term CV risk More causal research is needed.
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Fascinating debate at #EpiLifestyle26: Should everyone become an “AI-ologist”? 🤖🧵 As AI rapidly integrates into research & patient care, the question isn’t if—but how we engage with it. Key arguments from both sides 👇 @AHAScience
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⚖️ What’s needed moving forward • Strong data infrastructure • Thoughtful business models • Regulatory modernization And critically—clinicians who understand both the promise and the pitfalls of AI. #EpiLifestyle26 @AHAScience
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🌍 Important question raised: What about the environmental + social impact of AI—especially for marginalized communities? As AI scales, we must consider equity, bias, access, and broader societal costs. Innovation must center those most at risk. #EpiLifestyle26 @AHAScience
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Insights from the CKM session at #EpiLifestyle26 🧵 From proteomics → risk prediction → real-world therapeutics, exciting work advancing how we understand and manage cardiometabolic risk. Highlights below 👇 @AHAScience
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📊 PREVENT risk score—beyond CVD Higher PREVENT scores were associated with increased risk of non-CVD outcomes as well. Those in the highest risk group progressed to non-CVD death 11–13 years earlier vs lowest risk. Risk prediction is expanding beyond single outcomes.
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This matters: PREVENT isn’t just a CVD tool—it reflects broader CKM health and multi-system risk. Opportunities to: • Improve risk communication • Guide intensity of follow-up • Support multidisciplinary prevention strategies
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