A large bunch of scientists studying Chaperone Mediated Autophagy at Albert Einstein College of Medicine @einsteinmed *tweets and views are our own*

Bronx, NY
Joined October 2021
Great science at the Glenn Symposium of Aging at @YaleWestCampus last Friday. Two great talks by Floralba and Kiya.
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Marta and Nader from our lab and Saba from @EAriasLab also presented wonderful posters 🎉✅
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Ana Maria will be speaking at the upcoming Autophagy in Health and Disease: From Mechanisms to Therapeutics conference, Feb 8-11, Banff, Canada The scholarship + short talk abstract application deadline has been extended, do not hesitate to apply by October 28! #KSAutophagy27
⏳ Deadline extended to 10/28! Protein degradation meet autophagy 🏔️ Scholarship + short talk abstract applications are open for #KSProximity27 + #KSAutophagy27, joint meetings in Banff, Feb 8–11, 2027. Links to submit in the first comment!
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#MeetingAlert Registration is now open for the SEFAGIA 2027 Congress, which will take place in Valencia-Alfara del Patriarca, from 3 to 5 February 2027. Register here: orexco.congressus.es/sefagia… We look forward to seeing you in Valencia!
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🎉TimePie Longevity Forum is featured in @NatureAging! Appreciation to all the experts who contributed to the conversations shaping the future of longevity. @KejunYing @AMCuervoLab @prof_horvath @gladyshev_lab @susanna_rosi @Vinz_Sorrentino, et al. nature.com/articles/s43587-0…
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Lots of Cuervitos in Spain at the Hallmarks of Aging conference🥰
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Decline of chaperone-mediated autophagy in aging impairs macrophage clearance of senescent cells nature.com/articles/s43587-0…
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A new review on chaperone-mediated autophagy in physiological homeostasis, disease & ageing has been publisehed; #Parkinsons gets a couple of mentions, but a useful overview of the biology & potential "gerotherapeutic" targets nature.com/articles/s41580-0…
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9. In a bleomycin model, early CMA activation reduced lung fibrosis, senescence and inflammatory markers, and reshaped the immune response. Timing mattered: early treatment was more effective than delayed treatment.
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10. Our findings identify CMA decline as a driver of senescent cell persistence and highlight CMA upregulation as a promising strategy to promote senescence resolution in aged organisms. Thank you to all our collaborators and to our funding. We hope you enjoy our study!
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