Neuroscience Postdoctoral Fellow at @harvardmed

Joined March 2010
A thorough and thoughtful summary of the features and limitations of our fused fiber photometry system by @AlexLegariaM @LexKravitz cell.com/cell-reports-method…
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Latest paper exploring motivation in obesity and underlying NAc circuits from the @LexKravitz lab! This work was vaulted over the finish line by our incredibly talented undergrad @YiyanPan 🍔🍕🥯🐁 biologicalpsychiatryjournal.…
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I’m excited to announce the latest paper from @LexKravitz lab in collab with @jones_g_parker lab. nature.com/articles/s41593-0…. Here, we show that calcium fiber photometry in striatum reflects nonsomatic changes in calcium.
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On a final note, I’d like to give a shout-out to all the peer-reviewers both from the journal and here on twitter. Their feedback was incredibly helpful, and it really reshaped the paper to be what it is now.
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Does anyone know of papers that analyze fiber photometry data in other way other than peri-event analysis or counting transients? If so, would you mind sharing refs?
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What features would you like to see in a python package for fiber photometry signal processing? I have a module that a few labs have found useful. I'm thinking about refining and expanding it, and to make it public. The emphasis is to make it as simple to use as possible.
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Reminder from @AlexLegariaM that striatal fiber photometry signals do not reflect somatic firing activity in comparison with endoscopic recording and in vivo ephys. Interpret those traces with caution! #IBNS2021
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Our FED3 paper from @LexKravitz lab just dropped in @eLife!! With co-lead authors @mohamedamrali93 and the Untwittered Tom Earnest, this open-source platform allowed us to collect home cage food intake and operant behavior data across multiple institutes. elifesciences.org/articles/6…
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Our most recent batch of FED3s, churning away during testing! We'll be presenting @LexKravitz's FED3 at Cool Tools for Science (@QuantoCancer), a showcase for innovative solutions for research. Register here to join us: cooltools.tecnico.ulisboa.pt…
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Alex Legaria retweeted
.@toodlejess and I are thrilled to post the latest paper from @Meaghan_Creed lab, out today in @NatureNeuro! @cerebellions, @bridge_balance_,Eric Casey,Tom Earnest, Leana Ramos, Hanna Silberberg, @godynyukLizzy, Olivia Uddin, @Lil_laurrrr, @ClaireLePichon rdcu.be/cebim
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Fiber photometry does not reflect spiking activity in the striatum biorxiv.org/cgi/content/shor… #biorxiv_neursci
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I knew it! jk, I thought “well maybe....🤔”, but awesome for @AlexLegariaM @jlicholai @LexKravitz for doing the hard work to say it out loud. – at University City, MO
Fiber photometry does not reflect spiking activity in the striatum biorxiv.org/cgi/content/shor… #biorxiv_neursci
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Excited to drop the latest preprint from @LexKravitz lab describing FED3 - a novel home cage compatible device for rodent feeding, operant behavior, triggered stimulation, and more! biorxiv.org/content/10.1101/…
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Alex Legaria retweeted
I am proud to join in the celebration of #OYWDay as a @OneYoungWorld Ambassador, alongside 9,000+ inspiring young leaders from around the world. @OneYoungWorld has instilled in me a strong desire to do good, paid or not, for the socio-economic uplift of my community’s needs.
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