Alex retweeted
Cold activates a BH2 metabolic network promoting longevity and proteostasis
nature.com/articles/s41586-0…
Alex retweeted
Anabolic inequality among whole protein foods
cdnsciencepub.com/doi/10.113…
Alex retweeted
Why do large dogs tend to live shorter lives than their smaller counterparts?
The answer may be written into their epigenome, according to a new study in Science. The findings reveal that larger and male dogs undergo accelerated molecular aging, with pronounced DNA methylation on the X chromosome and at transposable elements.
Learn more: scim.ag/3VZtl3f
ALT A flowchart of the Dog Aging Project. It includes graphics of dogs, DNA, and data charts. Part A shows dog graphics with stars indicating enrollment locations. Part B features a chart of dog ages by size. Part C has box plots for types of dogs. Part D displays a graph of methylation changes over years.
Alex retweeted
More sets ≠ more gains. 💪
A 12-week study in trained women found no significant advantage of increasing training volume every 2 vs. 4 weeks for muscle growth or strength.
Progression doesn’t always require more sets.
researchgate.net/publication…
Alex retweeted
Longer lipids mark aging and constrain lifespan
👉 “… we identify elongation of lipid acyl chains as a conserved hallmark of aging across mice, Caenorhabditis elegans, Drosophila and humans.
Similar lengthening occurs during the progression of human heart disease, whereas dietary restriction shortens cardiac lipids in mice.
Integrated analyses reveal that aging is characterized by a shift toward longer lipids accompanied by depletion of shorter species, indicating ratiometric remodeling.
Following this, we identify the lipid remodeler Plb1 as a regulator of this process, with expression correlating with lifespan in mice and genetic analyses supporting a causal role in human frailty.
In C. elegans, Plb1 knockdown reverses lipid elongation and extends lifespan in a lipid-length-dependent manner.
Together, these findings establish lipid chain length remodeling as a conserved, actionable hallmark of aging.”
👨🏻⚕️nature.com/articles/s43587-0…
Alex retweeted
Recent paper from our group on muscle growth and local muscular endurance
link.springer.com/article/10…
Alex retweeted
The Power of Analytical Meditation - His Holiness the Dalai Lama shares how decades of analytical meditation gradually transformed his own emotions, until attachment and anger nearly disappeared. The key, he explains, is not prayer but investigation: examining different, even opposing views and making full use of our intelligence to train the mind. Video originally recorded on February 5, 2017.
Alex retweeted
Randomized controlled trial of resistance exercise and brain aging clocks
"Resistance exercise training decelerates brain ageing, as indexed by brain clocks, reinforcing its role as a preventive strategy for brain health."
link.springer.com/article/10…
Alex retweeted
Contraction type dependence of serial sarcomere addition following resistance training biorxiv.org/content/10.64898…
Alex retweeted
Music helps soothe the brain when we are stressed
Music doesn’t just mask stress; it guides our brains back to a calm state
scientificamerican.com/artic…
Alex retweeted
Women who delivered very preterm had vitamin D levels about 25% lower than women who delivered at term.
Average 25(OH)D was 26.2 ng/mL among births before 32 weeks, compared with 34.8 ng/mL at term. Women delivering between 32 and 36 weeks also had lower levels, averaging 31.3 ng/mL.
Vitamin D is involved in placental biology and immune and inflammatory regulation - pathways that could plausibly influence the timing of birth. And the pattern of progressively lower vitamin D with earlier delivery strengthens the case for testing whether optimizing maternal vitamin D status can improve pregnancy outcomes.
Alex retweeted
What is important is not so much how long you live as whether you live a meaningful life. This doesn’t mean accumulating money and fame, but being of service to your fellow human beings. It means helping others if you can, but even if you can’t do that, at least not harming them.
Alex retweeted
The Health Benefits of Exercise: Molecular and Cellular Mechanisms
onlinelibrary.wiley.com/doi/…
Alex retweeted
The more you help others the calmer your mind will be. You will be able to overcome misdeeds committed in relation to others. Familiarizing your mind with kindness and compassion yields peace of mind, which makes you happier and even improves your physical health.
Alex retweeted
This man walked for 6 straight days, covered 338 miles
pmc.ncbi.nlm.nih.gov/article…
Alex retweeted
Myokines as molecular mediators of the muscle-brain axis: Mechanisms linking sarcopenia to cognitive decline and implications for preventive strategies in ageing - A narrative review
sciencedirect.com/science/ar…
Alex retweeted
Exercise & naps protected memory from the effects of sleep loss, but via distinct brain mechanisms: buff.ly/bxUXJtF
Alex retweeted
Food-Derived Omega-3 Fatty Acids and Cognitive Aging: Integrating Nutritional Neuroscience and Geroscience
mdpi.com/2072-6643/18/16/259…
Alex retweeted
Effects of exercise snacks on cardiorespiratory fitness, body composition, and blood lipids in adults across different age groups: a systematic review and meta-analysis
pmc.ncbi.nlm.nih.gov/article…
Alex retweeted
Dietary bioactive compounds and inflammaging: Pro-inflammatory triggers and geroprotective countermeasures
pubmed.ncbi.nlm.nih.gov/4242…
