Alexandra Davies (@Alex_Doune) header
Alexandra Davies (@Alex_Doune) profile picture

Lecturer & group leader @FBMH_UoM, @MCF_UoM. Cell biology, proteomics, rare disease, #CureAP4

Manchester, England
Joined November 2015
Photo by Alexandra Davies (@Alex_Doune)Photo by Alexandra Davies (@Alex_Doune)Photo by Alexandra Davies (@Alex_Doune)Photo by Alexandra Davies (@Alex_Doune)Photo by Alexandra Davies (@Alex_Doune)Photo by Alexandra Davies (@Alex_Doune)Photo by Alexandra Davies (@Alex_Doune)Photo by Alexandra Davies (@Alex_Doune)Photo by Alexandra Davies (@Alex_Doune)Photo by Alexandra Davies (@Alex_Doune)
What a year it's been for the Davies Lab v1.0! Our 1st year in Manchester @MCF_UoM comes to a close. We're wishing congratulations to Jani and Emily for completing their degrees and welcoming Zac to the team. And Juliet just aced her 1st year viva! #dreamteam 🙌🔬🌈🎉
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The number of people living with a rare disease is equivalent to the third largest country in the world. 🌎 On #RareDiseaseDay, we aim to highlight their voices and raise awareness about their experiences. Download our Infographics: rarediseaseday.org/downloads…
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Are you an early-career researcher working in an area covered by @J_Cell_Sci and would like to attend a #microscopy training course? The next deadline is 22 November to apply for a £1,000 JCS-FocalPlane Training Grant. biologists.com/grants/jcs-fo… @focalplane_jcs
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Thanks @TheCoxLab #MQSS2024 organisers and speakers. My lab members (hiding at the back) had an incredible crash course in #massspec #proteomics data analysis! Kudos 🙌
MaxQuant Summer School 2024 #MQSS2024 in Munich was a great success! Thanks to all participants and speakers! You can now watch selected presentations on our YouTube channel (youtube.com/@MaxQuantChannel) . Stay tuned,we're already organizing next year’s one! #proteomics #TeamMassSpec
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Fab to see this exciting work out on @biorxivpreprint. Congrats 🎉 @MAFesenko, @moore_cell, @clathrin and team. Now, why am I suddenly craving skittles?! 🌈😂
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Exciting new #HSP #raredisease research from @ReidLab_HSP. Congratulations Eliska and the rest of the team! 👏
Our latest thing: Atlastin-1 regulates endosomal tubulation and lysosomal proteolysis in... sciencedirect.com/science/ar…
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Wow! This looks incredible! 🔬
Out at @naturemethods just now! nature.com/articles/s41592-0… We present #SN2N, a flagship level unsupervised denoising solution. It’s fully competitive with supervised learning without needing large training-set and clean ground-truth, using 1 noisy frame for training. (1/n)
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We are searching for an outstanding researcher to join the @LabBuckley. The successful candidate will use optogenetic, live imaging and quantitative analysis approaches to understand how mechanics and biochemical signalling shape epithelial organs. jobs.ac.uk/job/DIH126/resear…
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Only two days left to apply to join my new lab at the University of Manchester @MCF_UoM @FBMH_UoM! #PleaseShare #Applynow
My lab @MCF_UoM is #hiring a Research Technician. I'm looking for someone with experience in #iPSC & #microscopy. You will be trained in #proteomics and the project will tackle the mechanisms underlying rare neurological diseases. Apply now! jobs.manchester.ac.uk/Job/Jo… #pleaseshare
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My lab @MCF_UoM is #hiring a Research Technician. I'm looking for someone with experience in #iPSC & #microscopy. You will be trained in #proteomics and the project will tackle the mechanisms underlying rare neurological diseases. Apply now! jobs.manchester.ac.uk/Job/Jo… #pleaseshare
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Alexandra Davies retweeted
1/7 @labs_mann and Georg Wallmann @GeorgWa are proud to announce alphaDIA, our open source, next generation DIA search engine. Check out the preprint @biorxivpreprint biorxiv.org/content/10.1101/…
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Was a pleasure to collaborate with my former PhD supervisor, Scottie Robinson @TheCIMR, on this fantastic paper, just out in @JCellBiol. 40 years after Scottie discovered the #clathrin adaptor AP-1, she is still revealing surprises about its function! doi.org/10.1083/jcb.20231007…
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Alexandra Davies retweeted
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Thanks to the Wahlig family for bringing us all together to learn about HSP. Another wonderful meeting! #TWS2024 #TreatHSP #raredisease
Wonderful Tom Wahlig Symposium on HSP research in Erlangen, Germany. What a great tradition!
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Was an absolute pleasure to host you @ScheffoldM
Back in Boston after 2 amazing weeks at Manchester learning Proteomics from @Alex_Doune as part of my project @DEF_Lab_HMS. So grateful to Alex for teaching me and to @Boehringer MD Fellowship for funding my stay. Still in awe of the exciting research and the enchanting city.
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Alexandra Davies retweeted
We have a 3-year @BBSRC postdoc available in Manchester @MCF_UoM @FBMH_UoM @UoMMIB to utilise #EPR spectroscopy to address protein dynamics with @A_Politis1 and @JeskoKoehnke on board. Deadline for applications is on the 5th of March. Please retweet jobs.manchester.ac.uk/Job/Jo…
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Message from our new member: @LabBuckley is searching for outstanding researchers to join us as we move to MCF. We use optogenetics within zebrafish brains and mESC models to study how cells build organs. Postdoc: jobs.ac.uk/job/DFP591/resear… RA: jobs.ac.uk/job/DFO443/resear…
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So excited to see this paper out! 🎊 Incredible work from @DEF_Lab_HMS using #protein #mislocalisation phenotypes as a #drugscreen to identify a drug that restores the cellular distribution of ATG9A in AP4-deficient neurons and increases #autophagy flux. So cool! #CureAP4 #neuro
This week we @BostonChildrens @FMKirbyNeuro report in @NatureComms a cell-based phenotypic high-throughput assay for AP-4-related #hereditaryspasticparaplegia. Screen of ~29K compounds with @Astellas identified BCH-HSP-C01 👉🏽 #raredisease @CureAP4 @CureSPG50 @SpasticParapleg
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