حمود عبدالكريم الموسى (@AlmousaHamoud) header
حمود عبدالكريم الموسى (@AlmousaHamoud) profile picture

حمود عبدالكريم الموسى

@AlmousaHamoud

‏‏‏‏‏‏‏‏‏‏‏‏‏إستشاري أمراض الحساسية و المناعة مستشفى الملك فيصل التخصصي و مركز الأبحاث Allergist and Immunologist King Faisal Specialist Hospital & Research cen

 الرياض
Joined May 2018
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  • Followers1.3K
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Photo by حمود عبدالكريم الموسى (@AlmousaHamoud)Photo by حمود عبدالكريم الموسى (@AlmousaHamoud)Photo by حمود عبدالكريم الموسى (@AlmousaHamoud)Photo by حمود عبدالكريم الموسى (@AlmousaHamoud)Photo by حمود عبدالكريم الموسى (@AlmousaHamoud)Photo by حمود عبدالكريم الموسى (@AlmousaHamoud)Photo by حمود عبدالكريم الموسى (@AlmousaHamoud)Photo by حمود عبدالكريم الموسى (@AlmousaHamoud)Photo by حمود عبدالكريم الموسى (@AlmousaHamoud)Photo by حمود عبدالكريم الموسى (@AlmousaHamoud)
حمود عبدالكريم الموسى retweeted
Casanova Lab (@casanova_lab) profile picture
Casanova Lab@casanova_labNov 12
1/ Excited to share our paper in @NEJM today, reporting that autoantibodies neutralizing type I IFNs (autoAb-IFN) underlie the fatal case of H7N7 avian flu in the Netherlands 23 years ago! #AvianFlu #BirdFlu nejm.org/doi/full/10.1056/NE…
Autoantibodies against Type I Interferons and Death from H7N7 Avian Influenza | NEJM

Autoantibodies against Type I Interferons and Death from H7N7 Avian Influenza | NEJM

The authors report autoantibodies neutralizing interferon-α, -ω, and -β in a man who died from H7N7 influenza and mutations in the viral proteins that may facilitate adaptation to humans.

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حمود عبدالكريم الموسى retweeted
Journal of Human Immunity (@jhumimmunity) profile picture
Journal of Human Immunity@jhumimmunityOct 20
Ali, Alazami, and Al-Mousa describe a novel case of human BCL10 deficiency with a 13-year follow-up after hematopoietic stem cell transplantation. Their findings expand the clinical and genetic spectrum of this ultra-rare immunodeficiency hubs.la/Q04BMlQL0 #HSCT
Image from Journal of Human Immunity (@jhumimmunity)
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حمود عبدالكريم الموسى retweeted
Casanova Lab (@casanova_lab) profile picture
Casanova Lab@casanova_labOct 21
HSCT works for BCL10 deficiency: BCL10 deficiency: Long-term immune reconstitution following hematopoietic stem cell transplantation rupress.org/jhi/article/3/1/…
BCL10 deficiency: Long-term immune reconstitution following hematopoietic stem cell transplantation

BCL10 deficiency: Long-term immune reconstitution following hematopoietic stem cell transplantation

Ali et al. describe a novel case of human BCL10 deficiency with a 13-year follow-up after hematopoietic stem cell transplantation. Their findings expand th

rupress.org
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Delighted to share our newly published article describing the world’s largest single-center experience with hematopoietic stem cell transplantation (HSCT) for DOCK8 deficiency frontiersin.org/journals/imm…
Frontiers | Hematopoietic stem cell transplantation for DOCK8 deficiency: durable immune reconsti...

Frontiers | Hematopoietic stem cell transplantation for DOCK8 deficiency: durable immune reconsti...

BackgroundDOCK8 deficiency is a severe autosomal recessive combined immunodeficiency characterized by recurrent infections, severe atopy, immune dysregulatio...

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Our results demonstrate excellent transplant outcomes, with an overall survival (OS) and event-free survival (EFS) of 91.5%, including an OS of 94.6% with matched related donors and 100% with matched unrelated donors.
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حمود عبدالكريم الموسى retweeted
Casanova Lab (@casanova_lab) profile picture
Casanova Lab@casanova_labAug 24
1/ We are excited to report in @PNASNews that autoantibodies neutralizing type I interferons underlie 35% of cases of Chikungunya virus (CHIKV) encephalitis or myelitis from a multiple cohort study. pnas.org/doi/10.1073/pnas.26…
Autoantibodies neutralizing type I interferons underlie a third of cases of Chikungunya virus...

Autoantibodies neutralizing type I interferons underlie a third of cases of Chikungunya virus...

Chikungunya virus (CHIKV) infection is typically not life threatening but may, in rare cases, affect the central nervous system (CNS). In three coh...

pnas.org
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حمود عبدالكريم الموسى retweeted
Saudi International Vaccination Professionals (@SaudiVaccine) profile picture
Saudi International Vaccination Professionals@SaudiVaccineMay 9
At #SIVF2026 — the Saudi Vaccine Awards 2026 honoring outstanding leaders and innovators in vaccination and public health. 🌍💉 Congratulations to all awardees for your remarkable contributions to advancing immunization and healthcare excellence.
Image from Saudi International Vaccination Professionals (@SaudiVaccine)
Image from Saudi International Vaccination Professionals (@SaudiVaccine)
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حمود عبدالكريم الموسى retweeted
Journal of Human Immunity (@jhumimmunity) profile picture
Journal of Human Immunity@jhumimmunity29 Dec 2025
#5 Kanegane et al review unresolved issues in the pathogenesis of X-linked agammaglobulinemia (XLA), incl. non-coding BTK variants, contiguous deletion syndrome, Helicobacter infection, non-infectious neurodegeneration, renal involvement & malignancies: rupress.org/jhi/article/1/1/…
Revisiting X-linked agammaglobulinemia

Revisiting X-linked agammaglobulinemia

Although the pathogenesis of XLA is well understood, several issues remain open for discussion. We describe several unresolved issues, including non-coding

rupress.org
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حمود عبدالكريم الموسى retweeted
Journal of Human Immunity (@jhumimmunity) profile picture
Journal of Human Immunity@jhumimmunity29 Dec 2025
#4 Type I IFN autoantibodies (auto-Abs) are associated w/ severe #COVID19. Peduti et al. reveal a 6.7% prevalence of auto-Abs in critically ill Brazilian patients, predominantly affecting older individuals: rupress.org/jhi/article/1/3/…
Prevalence and association of type I IFN autoantibodies with clinical outcomes in critically ill...

Prevalence and association of type I IFN autoantibodies with clinical outcomes in critically ill...

Type I IFN autoantibodies (auto-Abs) impair antiviral immunity and are associated with severe COVID-19. This study reveals a 6.7% prevalence of auto-Abs in

rupress.org
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حمود عبدالكريم الموسى retweeted
Journal of Human Immunity (@jhumimmunity) profile picture
Journal of Human Immunity@jhumimmunity29 Dec 2025
#3 30-year @ESIDsociety registry analysis of 30,628 patients' longitudinal datasets show results of robust epidemiological studies on natural courses supporting newborn screening and future AI applications in IEI: rupress.org/jhi/article/1/3/…
Inborn errors of immunity: Manifestation, treatment, and outcome—an ESID registry 1994–2024 report...

Inborn errors of immunity: Manifestation, treatment, and outcome—an ESID registry 1994–2024 report...

Worldwide, most patient registries for IEI are national, with limited geographical/temporal scope. This 30-year ESID registry analysis of 30,628 patients’

rupress.org
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حمود عبدالكريم الموسى retweeted
Journal of Human Immunity (@jhumimmunity) profile picture
Journal of Human Immunity@jhumimmunity29 Dec 2025
#1: Poli et al. present the 2024 update of the @iuis_online classification of human #InbornErrorsOfImmunity incl. 67 novel monogenic defects & 2 new phenocopies. rupress.org/jhi/article/1/1/…
Human inborn errors of immunity: 2024 update on the classification from the International Union of...

Human inborn errors of immunity: 2024 update on the classification from the International Union of...

Here we provide a comprehensive update to the classification of monogenic immune disorders.

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حمود عبدالكريم الموسى retweeted
Journal of Human Immunity (@jhumimmunity) profile picture
Journal of Human Immunity@jhumimmunity29 Dec 2025
#2 Bousfiha et al. present a decision tree-based diagnostic guide to human #InbornErrorsOfImmunity for physicians based on the 2024 update of the @iuis_online expert committee: rupress.org/jhi/article/1/1/…
The 2024 update of IUIS phenotypic classification of human inborn errors of immunity

The 2024 update of IUIS phenotypic classification of human inborn errors of immunity

Here, we report the 2024 update of the phenotypic classification by the International Union of Immunological Societies (IUIS) expert committee on inborn er

rupress.org
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حمود عبدالكريم الموسى retweeted
Journal of Human Immunity (@jhumimmunity) profile picture
Journal of Human Immunity@jhumimmunity29 Dec 2025
As 2025 wraps up, we're proud to celebrate the inaugural year of the Journal of Human Immunity (JHI)! 🎉Here are our 5 most-read articles so far 👇🧬
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حمود عبدالكريم الموسى retweeted
Casanova Lab (@casanova_lab) profile picture
Casanova Lab@casanova_lab21 Sep 2025
Replying to @LangloisLab
@LangloisLab and I consider the potential impact of human inborn errors of immunity on the evolution of viruses, including the onset of viral pandemics: The potential impacts of human genetics on virus emergence | PNAS pnas.org/doi/10.1073/pnas.25…
The potential impacts of human genetics on virus emergence | PNAS

The potential impacts of human genetics on virus emergence | PNAS

Human monogenic traits can confer resistance to viral infection in exposed individuals or predisposition to severe disease in infected individuals....

pnas.org
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حمود عبدالكريم الموسى retweeted
Rockefeller U. Press (@RockUPress) profile picture
Rockefeller U. Press@RockUPress6 Jun 2025
🔔 @jhumimmunity is delighted to share the abstracts from the 4th Congress of the Arab Society for Primary Immunodeficiencies #ARAPID, which took place April 24–26 in Casablanca. Explore the latest advancements in #PID clinical practice & research 👉 hubs.ly/Q03r1Z_k0
Image from Rockefeller U. Press (@RockUPress)
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Thrilled to share our collaborative work in @Pediatric Rheumatology! We've proposed a definition for Monogenic Inflammatory Immune Dysregulation Disorders (MIIDDs). DOI: doi.org/10.1186/s12969-025-0…
Image from د. سليمان المعيوف. Sulaiman M Al-Mayouf, MD (@sulaimanm2020)
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قامت وزارة الصحة بمراجعة جدول التطعيم الوطني في عام 2019، حيث تم تأجيل إعطاء لقاح السل (BCG) من الولادة إلى عمر 6 أشهر، بهدف إتاحة الوقت لتشخيص أمراض نقص المناعة الأولية قبل التطعيم frontiersin.org/journals/imm…
Frontiers | The effects of postponing BCG vaccination on the risk of BCG-related complications...

Frontiers | The effects of postponing BCG vaccination on the risk of BCG-related complications...

IntroductionThe Bacillus Calmette–Guérin (BCG) vaccine is widely used to prevent tuberculosis but is associated with significant complications in patients wi...

frontiersin.org
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في هذه الدراسة التي أجريناها انخفضت نسبة المضاعفات المرتبطة بلقاح BCG لدى الأطفال المصابون نقص المناعة الخلقي المركب الشديد بشكل ملحوظ بعد تعديل السياسة، من 46.1% إلى 2.6% مما يبرز أهمية تعديل جداول التطعيم لتتناسب مع طبيعة السكان و الأمراض المستهدفة
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وتُعد سياسة التطعيم المعدلة في المملكة العربية السعودية نموذجًا يمكن الاستفادة منه لتحسين استراتيجيات التحصين في المناطق التي تنتشر فيها أمراض خلل المناعة الوراثية
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The effects of postponing BCG vaccination on the risk of BCG-related complications among patients with severe combined immunodeficiency disease in Saudi Arabia frontiersin.org/journals/imm…
Frontiers | The effects of postponing BCG vaccination on the risk of BCG-related complications...

Frontiers | The effects of postponing BCG vaccination on the risk of BCG-related complications...

IntroductionThe Bacillus Calmette–Guérin (BCG) vaccine is widely used to prevent tuberculosis but is associated with significant complications in patients wi...

frontiersin.org
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Considering the high incidence of SCID in Saudi Arabia, the Ministry of Health revised its national vaccination schedule in 2019, postponing BCG administration from birth to 6 months of age to enable time for the diagnosis of primary immunodeficiency diseases before vaccination
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The revised vaccination policy of Saudi Arabia provides a model for optimizing immunization strategies in regions with a high prevalence of inborn errors of immunity.
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