@AndyTruman4

Group Leader @JohnInnesCentre. Science and other things. Norwich. He/Him.

 Norwich, England
jic.ac.uk/people/dr-andrew-truman/
Joined October 2017
  • Tweets1.7K
  • Following1.5K
  • Followers1.3K
179Media
New pre-print from the group 🥳 We use targeted genome mining to show that the plant pathogen Rhodococcus fascians makes the antibiotic lydiamycin. The BGC information then informed the discovery of multiple key features relating to the molecule 1/4 biorxiv.org/cgi/content/shor…
1
15
34
4,054
Andy Truman retweeted
Joe Sallmen@JWSallmenII7 Jan 2025
Check out what I was up as I was nearing the end of my postdoc! Big congrats and thanks to the cryo-em king @casub1 for all the incredible work together and to @SusanSchlimpert for letting me work on this project early on until the end of my time there!!!
casu_b@casub17 Jan 2025
🚨 New Research Alert! 🚨 How do bacterial contractile injection systems (CIS) like those in Streptomyces coelicolor function without extracellular targets? 🤔 🧬 We uncovered the role of CisA, a membrane adaptor protein critical for CIS-mediated cell death.
1
8
1
23
2,326
Just in time for the holidays Convergent Evolution of the Antimycobacterial Lasso Peptide Triculamin biorxiv.org/content/10.1101/…

Convergent Evolution of the Antimycobacterial Lasso Peptide Triculamin

Triculamin is a ribosomally synthesized and post-translationally modified peptide (RiPP) lasso peptide with potent antimycobacterial activity, produced by an unusual, non-canonical biosynthetic gene...

biorxiv.org
1
8
20
2,258
It was a pleasure @michael_brigham 😀 Well done on a great thesis.
Michael Brigham@michael_brigham28 Nov 2024
Thrilled to have passed my PhD viva yesterday! Many thanks to @AndyTruman4 and @wbturnbull for a great discussion, and of course thanks to collaborators, lab members and my supervisors @ryanfseipke, Glyn and Mike for their support over the years
2
391
While the BGC is on the R. fascians pathogenicity plasmid, we could not detect a direct role in pathogenicity for the molecule. Instead, it contributes to microbial competition during plant colonisation. 3/4
1
202
The paper represents the excellent efforts of Jonny Ford, a previous PhD student in the group, along with multiple collaborators, including PDF expertise from the Rodnina group, plus Isolde Francis and Danny Veerecke, who provided some hugely important R. fascians expertise 4/4
1
180
Andy Truman retweeted
Tatsuya Nobori@nobolly11 Nov 2024
I thought it was a bug on my RSS reader. Turns out, it's not
1
1
1
6
3,465
Come join us at JIC!
John Innes Centre@JohnInnesCentre8 Nov 2024
VACANCY - We’re seeking a visionary Group Leader for plant-arthropod interactions research, including insects, with expertise in genetic processes, biochemical pathways, or evolutionary and population genomics. okt.to/AK9uG3 Deadline - 3 January 2025 @NorwichResearch
1
8
8
2,740
Was fun to introduce a new student to this classic of a paper from Merv Bibb and colleagues at JIC published 40 years ago (!!). Such an elegant observation and still useful at "seeing" genes that have been misannotated or missed entirely. sciencedirect.com/science/ar…
2
6
29
3,592
For goodness sake. Despite big tax rises overall chancellor has done it again. Fuel duty frozen and "temporary" 5p cut kept. This government is supposed to care about climate change. And I'm willing to bet fiscal numbers assume increases into the future. How much longer?
153
318
60
1,575
327,681
ICYMI, I maintain a list of conferences for the natural product community! tinyurl.com/NP-events I've stopped doomscrolling here, which means I don't see events. I expect a wave of announcements in the new year. If you know about or are organizing an event, please reach out!

Natural Products Conferences, Symposia, and Workshops

docs.google.com
1
14
34
3,145
Please RT. 1x postdoc and 1xPhD position available in our group to study the role of NLR-like proteins in cellular development and antibiotic production in Streptomyces. Postdoc: shorturl.at/f8NTN PhD position: shorturl.at/qCFmN Email me for more information.
5
142
3
182
31,921
If your degree is 'not good value for money', then don't do it. But in science, after 12 years of frozen fees, we simply can't afford to deliver our current high-contact high skill degree courses. But government, not fees, should be paying more for key degrees. #r4today
6
8
1
129
11,010
Today @SciTechgovuk published the UK Position Paper on the 10th EU Research and Innovation Framework Programme. Read it here: gov.uk/government/publicatio…
A graphic that includes the following quote from Professor Christopher Smith, UKRI International Champion: “This position paper signals the continuing importance of our collaboration with European partners, fostering innovation and advancing research that will benefit us all. At UKRI, we believe that working together across borders is vital for tackling global challenges and driving sustainable growth."

ALT A graphic that includes the following quote from Professor Christopher Smith, UKRI International Champion: “This position paper signals the continuing importance of our collaboration with European partners, fostering innovation and advancing research that will benefit us all. At UKRI, we believe that working together across borders is vital for tackling global challenges and driving sustainable growth."

Department for Science, Innovation and Technology@SciTechgovuk26 Sep 2024
We are setting out the UK's initial position on FP10: the successor to Horizon Europe Research is critical to boosting health, growing the economy & reaching net zero. It's in all our interests that the structures supporting our innovators are the best they can be gov.uk/government/publicatio…
A glowing Earth with network connections, overlaid with text "UK sets out aspirations for Horizon Europe successor."

ALT A glowing Earth with network connections, overlaid with text "UK sets out aspirations for Horizon Europe successor."

19
31
11,637
#ICYMI We hope everyone who attended our Applied Molecular Microbiology Summer School at @IUCDubrovnik @institutrb had an amazing time. Judging from your posts and photos, you certainly did! Roll on the next one in 2026! 🦠🔬
1
4
1
9
2,769
Delighted that a collaboration with @Nairlab_UIUC is now online @nchembio Nucleobases are common in biology but not in peptides. In this work, a nucleobase-peptide hybrid is generated from a ribosomal precursor peptide via YcaO domain protein catalysis. nature.com/articles/s41589-0…
1
17
62
4,035
Great to have our Director introduce our first @JohnInnesCentre Diversity lecture (sponsorship by JIF) given by Helen Musgrove from @LexxicLtd. Along with our @BBSRC connecting culture project planning to see some real changes to celebrate and value neurodiversity.
1
1
6
1,313
Excellent first half of our @JohnInnesCentre @institutrb Summer School in beautiful Croatia (although currently having heavy thunderstorms ⛈ ) at the @IUCDubrovnik
5
25
1,423
Very happy that our work on understanding tropolone biosynthesis is now out in @mbiojournal Great work from the PhD of @AlasterMoffat and some excellent biochemistry from @TeufelLab #biosynthesis #Pseudomonas journals.asm.org/doi/10.1128…

Understanding the biosynthesis, metabolic regulation, and anti-phytopathogen activity of 3,7-dihy...

Pseudomonas bacteria produce various potent chemicals that influence interactions in nature, such as metal-binding molecules, antibiotics, or plant hormones. This ability to synthesize bioactive...

journals.asm.org
13
27
2,642
Load more