Anne Liu (@AnneLiuMD) profile picture

The Bugs, the Drugs, and the Cells. Immunocompromised host infectious diseases physician. Allergist/immunologist. Stanford, CA.

Joined October 2013
Will omalizumab do to food oral immunotherapy what dupilumab did to aspirin desensitization? #AAAAI24
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The only antibody therapy known to neutralize SARS-CoV-2 variants XBB.1 BQ.1.1 in vitro + available under FDA EUA for immunocompromised COVID is convalescent plasma from vaccinated/boosted donors. Grateful to @giveblood for making CCP available!
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We are so excited to gain such an incredible new class of incoming fellows today! Congratulations to each of you on all you have already accomplished. We cannot wait for you to join our Stanford ID family in a few short months!
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Great news! Novavax COVID-19 vaccine just got authorized for 1st booster! Doesn’t matter what u got for 1st/2nd (primary series). Lots of ppl who had oddball symptoms after mRNA or J&J of unclear attribution have waited for this. Uses protein subunit tech, not mRNA.
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Allergies are weird!! Thanks, @KatherineJWu, for “shedding” some light on cat allergies. The human body is a strange place. The more we learn, the stranger it gets. Glad your B cells and mast cells have made their peace with Calvin and Hobbes.
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“Allergy…is a hot, complicated mess—a common fixture of modern living that many of us take for granted, but that remains, in so many cases, a mystery.” @KatherineJWu #AIMedEd @rubin_allergy @AnneLiuMD @nowak_wegrzyn theatlantic.com/science/arch…
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Intradermal delivery of vaccines? Calling all allergy nurses!!
Replying to @kavitapmd
The DOWNSIDE of going from single to multi dose vials is wastage/also many of us in primary care still do PPD skin test (to test for TB) which is intradermal,but not all health workers are trained to do this.Nevertheless its an incredible boost for a dwindling supply of vax -fin
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Novel COVID variants are likely arising from immunocompromised people. ~2-3% of the population is immunocompromised. ~100% of the population is impacted by novel variants. We need to invest in preventing infection in immunocompromised people — globally.
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It enrages me to hear immunocompromised patients say that their doctors told them they shouldn’t get vaccinated against covid because being immunocompromised means they won’t benefit from vaccination
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In case there isn’t enough to be enraged about these days
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Hearing many misconceptions about Evusheld. Here are some facts: You don’t need to check COVID antibodies before getting Evusheld. You can benefit from Evusheld even if your immune system is too weak to benefit from COVID vaccination.
Sadly it is June 2022 and COVID meds are still being underused or used incorrectly. To clarify: Eligibility for paxlovid is determined by risk factors, NOT by severity of disease. Evusheld used to prevent COVID-19 in immunocompromised (many) or vax-allergic people (few).
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(And you should.) You can get Evusheld after a COVID infection if you are at risk of reinfection. Evusheld is not a vaccination. It doesn’t stimulate your immune system to make antibodies.
People are surprised to learn these conditions make them eligible for paxlovid: * High blood pressure (half of U.S. adults) * Body mass index >25 (over 70% of U.S. adults!) * Physical inactivity / sedentary lifestyle * Asthma (moderate+) * Former smoker * Depression
Sadly it is June 2022 and COVID meds are still being underused or used incorrectly. To clarify: Eligibility for paxlovid is determined by risk factors, NOT by severity of disease. Evusheld used to prevent COVID-19 in immunocompromised (many) or vax-allergic people (few).
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High risk people who get covid are telling me that their doctors told them they aren’t sick enough for paxlovid and need to wait 5 days to see if they get worse before can get a prescription. That is wrong. Antivirals work better when started sooner.
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Sadly it is June 2022 and COVID meds are still being underused or used incorrectly. To clarify: Eligibility for paxlovid is determined by risk factors, NOT by severity of disease. Evusheld used to prevent COVID-19 in immunocompromised (many) or vax-allergic people (few).
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May the 4th be with us
MORALLY OUTRAGED by the leaking of the Death Star plans!!! (Not the building of the giant planet-destroying death laser -- that's fine.)