@BIPOCinCompGen

Research by Black, Indigenous, and People of Color scientists in computational genomics including pop gen, stat gen, human gen, etc.

 [email protected]
Joined June 2020
  • Tweets118
  • Following20
  • Followers687
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Excited to share our latest contribution to mapping genes for traits using phylogenies #PhyloG2P #PhyloGWAS @MolBioEvol! PhyloAcc-GT incorporates gene tree variation and improved ease of use ! academic.oup.com/mbe/article… phyloacc.github.io/ @timsackton, @greggwcthomas
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Out now in @CellCellPress! doi.org/10.1016/j.cell.2023.… Historically marginalized student representation drastically drops from undergrad to grad school. Are underrepresented students unqualified? Or are grad school admissions unnecessarily confusing, costly, & gatekeeping? 1/🧵
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BIPOCinCompGen retweeted
David Tang@dtang200030 Nov 2022
super excited to share our new paper on polygenic epistasis! we introduce a new model and show how structured statistical epistasis can help us study complex trait biology. huge thanks to my friend and lab-mate @studyjeromics, and my mentor @andywdahl! biorxiv.org/content/10.1101/…

Factorizing polygenic epistasis improves prediction and uncovers biological pathways in complex...

Epistasis is central in many domains of biology, but it has not yet proven useful for complex traits. This is partly because complex trait epistasis involves polygenic interactions that are poorly...

biorxiv.org
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Are you interested in using deep learning for genomic predictions? Join my lab! please RT
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1/8 25 years ago, today (Oct 24, 1997), 'Gattaca' was released. Me & @DocEdge85 chose to commemorate the event w/ a technical perspective recently published in GENETICS @GeneticsGSA Here I'll just post several items related to the broader project. academic.oup.com/genetics/ad…

Gattaca as a lens on contemporary genetics: marking 25 years into the film’s “not-too-distant”...

In this article, Ogbunugafor and Edge commemorate the 25th anniversary of the release of the film Gattaca, using the moment as an opportunity to examine co

academic.oup.com
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BIPOCinCompGen retweeted
Ryan Hernandez@rdhernand22 Oct 2022
Are you an undergrad thinking about grad school in a biology-related field? Do you identify as a member of a historically excluded group in STEM, grow up with in a disadvantaged background, or experience an ongoing disability? Come join our amazing @UCSF_PROPEL community!🧵
UCSF PROPEL@UCSF_PROPEL22 Oct 2022
Incredibly excited to announce the 2023 @UCSF Virtual Matchmaking Event for Postbaccalaureate Scholars on Feb 1, 2023! Register by Jan 6! Come meet 6+ faculty with shared research interests, and join our amazing and thriving community! Visit justice.ucsf.edu for more info
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BIPOCinCompGen retweeted
Roshni Patel@RoshniAPatel21 Oct 2022
cannot stop thinking about this paper -- the misuse and misinterpretation of genetics research is a hard and complicated problem but it is not hard and complicated to commit to having real, honest discussions about the societal implications of our work!
Sohini Ramachandran@s_ramach19 Oct 2022
Replying to @s_ramach
Our message: What if we routinely discussed — with each other, with colleagues in other disciplines, with our students, and with the public — the potential harmful impacts of our work? 3/3
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It was a pleasure to work with and learn from @JedMSP @HennLab @dralhindi and @Nature in the processing of writing this commentary: nature.com/articles/d41586-0…. Thanks especially to @JedMSP for suggesting a lead photo centering the victims of hate crimes by white nationalists. 1/3
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Thanks for celebrating #BIGxWeek with us, @TheACMG! Check out the link in the tweet below to some FREE #BIGxScience articles on Black women and breast cancer.
ACMG
@TheACMG5 Oct 2022
In celebration of #BIGxWeek and #BIGxScience Day, @GIMJournal ACMG’s official journal is making these two special articles focused on Black women and #breastcancer available FREE to all this month. Search the article titles here: gimjournal.org/ @BlackInGenetics #DEI
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#BIGxWeek starts next week with a roll call on October 3rd! Are you ready, #blackingeneticsrollcall?
This is an infographic announcing Monday’s BIGxWeek topic: BIG Roll Call. The information reads “Introduce yourself to the BIG community! Be sure to use the hashtag, #blackingeneticsrollcall” and indicates the date this will be taking place, Monday, October 3, 2022. The information about this day is written above a DNA double helix that is colored different shades of brown. At the the bottom left corner has text that includes our hashtag for the week, #BIGxWeek. The upper left corner of the infographic shows the Black in genetics logo, which depicts a woman of African descent and the curls of her hair are DNA helices. She is looking down and has a gold earring visible. This logo is drawn in white inside a black circle. Beneath the woman is the BIG twitter handle, @blackingenetics.

ALT This is an infographic announcing Monday’s BIGxWeek topic: BIG Roll Call. The information reads “Introduce yourself to the BIG community! Be sure to use the hashtag, #blackingeneticsrollcall” and indicates the date this will be taking place, Monday, October 3, 2022. The information about this day is written above a DNA double helix that is colored different shades of brown. At the the bottom left corner has text that includes our hashtag for the week, #BIGxWeek. The upper left corner of the infographic shows the Black in genetics logo, which depicts a woman of African descent and the curls of her hair are DNA helices. She is looking down and has a gold earring visible. This logo is drawn in white inside a black circle. Beneath the woman is the BIG twitter handle, @blackingenetics.

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Have you ever wondered about whether epistasis shapes human quantitative traits? Is chasing it a fool's errand? Thanks to the wonderful postdoc program @ICERM, @lorin_crawford and I have dropped another single on @biorxivpreprint, co-led by Greg Darnell & @SLiMulateshady. 1/4
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Preprint up: Community co-design of the @StanfordHealth Preventive Genomics Program- partnering with community members to build a clinical program for polygenic scores. Big thanks to our community participants and co-authors for their expertise & time tinyurl.com/SHCPGP 1/5
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✨ Excited to share our most recent work on population genetics in Southwest India! ✨ 🗣️ We ask: What is the relationship between genetic & oral histories in this region? 🧬 biorxiv.org/content/10.1101/… 🧵 A thread with some highlights …

Integrating genetic and oral histories of Southwest Indian populations

India is home to thousands of ethno-linguistically distinct groups, many maintaining strong self-identities that derive from oral traditions and histories. However, these traditions and histories are...

biorxiv.org
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BIPOCinCompGen retweeted
Roshni Patel@RoshniAPatel8 Dec 2021
Thrilled to share my first paper from my PhD, advised by @jkpritch and in close collaboration with my co-first author @shailamusharoff, on testing for differences in causal variant effect sizes across populations. biorxiv.org/content/10.1101/… (1/9)

Effect sizes of causal variants for gene expression and complex traits differ between populations

Despite the growing number of genome-wide association studies (GWAS) for complex traits, it remains unclear whether effect sizes of causal genetic variants differ between populations. In principle,...

biorxiv.org
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Come to my #ASHG21 poster today! We develop a novel statistical approach that leverages admixed genomes and find that causal variant effect sizes differ between populations. Monday Oct 18, 5:30-6:30pm EDT, PrgmNr 3719, with co-authors @RoshniAPatel @tassimes @sbmontgom @jkpritch
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BIPOCinCompGen retweeted
Mashaal Sohail@mashaals18 Oct 2021
Very excited and honored to give a plenary talk at #ASHG2021 tomorrow on my work with @jnovembre titled “Investigating relative contributions to complex trait architecture from sequence elements originating across multiple evolutionary timescales” @ 1.40-2.00pm ET
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Happy Indigenous Futures Day 🔮✊🏽❤️
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🧬 #BIGxWeek Trivia Question 2 🧬 What is the name of the group which was initiated in 2010 in order to study African genomics? Respond here 👇🏿👇🏾👇🏽 forms.gle/pQaNDDW7EHe6AkWJ9

BIGxWeek Trivia Question 2

Please answer the trivia question below. One winner randomly selected from those who answered correctly will win a BIGx Mug! https://www.etsy.com/listing/1088228855/bigx-color-pop-mug?ref=shop_home...

docs.google.com
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BIPOCinCompGen retweeted
Ryan Hernandez@rdhernand4 Aug 2021
#HannaGrayFellows is a great program for early career scientists, with a specific focus on those from gender, racial, ethnic, and other groups underrepresented in the life sciences, including individuals from disadvantaged backgrounds. Let’s go @BIPOCinCompGen!
HHMI
@hhmi_science4 Aug 2021
Applications are OPEN through December 1, 2021 for the next round of the #HannaGrayFellows Program. Learn more and please spread the word! More info here: bit.ly/3rSIYGE
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✅Check out our last review about the genomic history of enslaved-African descendant populations in the Americas. xitter.cf/hmg_journal/status/139…
Human Molecular Genetics@hmg_journal19 May 2021
A review by @CesarFortesLima and Paul Verdu examines anthropological genomics studies published over the past 15 years focusing on the history of enslaved-African descendant populations in the Americas: doi.org/10.1093/hmg/ddaa271
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