Working towards understanding and treating neurodegeneration
Joined December 2020
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BrentRyanLab retweeted
We're BACK! 🥳
SCMND returns for 2027! 🎉🎉
Agenda, Speakers, Registration & Abstract submission now available on scmnd.com/
#iPSC #Organoids #Neurodegeneration #StemCell
BrentRyanLab retweeted
Academic publisher Elsevier's profit margin compared to Apple, Google, and Microsoft
Apple: 28%
Google: 25%
Microsoft: 34%
Elsevier: 37% with a revenue of $3.9 billion.
Elsevier's payment to academic authors and reviewers: $0
BrentRyanLab retweeted
Our paper on microglial response to, processing and release of tau is finally published! 👩🔬 It was a huge collaborative effort and we are proud to see it in the journal Alzheimers and Dementia. There is RNAseq, Cryo-ET, proteomics and more! Do check it out doi.org/10.1002/alz.71337
BrentRyanLab retweeted
I'm moving to Purdue University as a tenured professor this summer! Excited to hire postdocs there and get a lab up and running with @wshenrx as co-lead.
More details: linkedin.com/posts/annecarpe…
I’ve spent 20 years working with mission-driven colleagues at the Broad Institute of MIT and Harvard, at the center of an incredible revolution of computational and molecular technologies. I want to close my time at the Broad with gratitude…
Details:
linkedin.com/posts/annecarpe…
BrentRyanLab retweeted
Excited to share a pre-print from a collaboration between my lab at NIH, Len Petrucelli's lab at University of Miami, and Shyamal Mosalaganti's lab at University of Michigan.
ALT CryoET of TMEM106B fibrils and colored segmentation showing protrusion of fibrils from within broken lysosomes in FTLD-GRN post-mortem brain.
BrentRyanLab retweeted
Writing now a ERC PoC I have some thoughts I would like to share here and open ( why not?) a discussion.👇🏼
BrentRyanLab retweeted
The tragedy of this is that it’s totally unnecessary - I think it’s a result of hasty (to put it politely) decision making at a level below ministers, and therefore will be fixable. But if it’s not fixed quickly the impact will be severe and there will be unpredictable consequences for physics as a whole in the U.K. And that is daft (again, polite language).
UK Science is heading towards a major, major crisis!
theguardian.com/science/2026…
BrentRyanLab retweeted
I'm excited to be speaking at The Festival of Genomics & Biodata 2026!
28-29th Jan 2026, ExCeL London
Free for most attendees! hubs.la/Q03JMvwd0
#FOG2026
BrentRyanLab retweeted
🌟Free Oxford lecture: the future of treatments for Alzheimer’s & other neurodegenerative diseases
🧠✨ Join us in Oxford for an @ARUKThamesV public lecture — an evening exploring groundbreaking research and future therapies for Neurodegenerative Diseases.
📅 Thu, 16 Oct 2025 | 18:00
🔗 eventbrite.co.uk/e/turning-s…
@ARUKscientist @OxfordDPAG #dementia #research #translation
BrentRyanLab retweeted
🧠✨ Join us in Oxford for an @ARUKThamesV public lecture — an evening exploring groundbreaking research and future therapies for Neurodegenerative Diseases.
📅 Thu, 16 Oct 2025 | 18:00
🔗 eventbrite.co.uk/e/turning-s…
@ARUKscientist @OxfordDPAG #dementia #research #translation
BrentRyanLab retweeted
Delighted to help create this event! Research is strongest when guided by those it aims to benefit. @AlzResearchUK #PPI #buildingbridges
Yesterday, we united lab scientists & people with lived experience of dementia in a workshop aimed at building bridges to make research more relevant & impactful. 🧠🔬
@AlzResearchUK @ParkinsonsUK
#communication #collaboration
BrentRyanLab retweeted
🌟 We’re hiring a Postdoctoral Fellow! 🌟
Join my lab @Sydney_Uni and help drive cutting-edge research in axon degeneration as part of the Snow Vision Accelerator.
@SnowMedical
usyd.wd105.myworkdayjobs.com…
BrentRyanLab retweeted
I spy with my little eye something that looks like exhausted microglia 👀👀👀 – at Indianapolis, IN
Single-cell epigen- & transcript-omic profiling of 3.5M cells from 384 brain samples across 6 regions in 111 #Alzheimers (& control) cases, reveals "widespread epigenome relaxation & brain-region-specific & cell-type-specific epigenomic erosion signatures"
cell.com/cell/fulltext/S0092…
BrentRyanLab retweeted
🎧 Professor Dame Carol Robinson joins @BBCRadio4’s Desert Island Discs to reflect on her life and career through eight memorable tracks.
From Pfizer at 16 to groundbreaking science at Oxford.
📻 Listen from 10 Aug → bbc.co.uk/programmes/m002gzq…
BrentRyanLab retweeted
A really wonderful evening at our local @PUK_Oxford community meeting hearing from @crassell2 on the politics of research funding and having some great conversations with PwP about the research questions we should be trying to answer! @OxfordPDCentre @ParkinsonsUK
BrentRyanLab retweeted
New research from the ProtectMove project (n=2364 #Parkinsons & 2909 controls) highlights the importance of copy number variants in PD (particularly in PARKIN) & suggest that rare CNVs in LRRK2 & RAB32 may contribute to disease risk & diagnostic potential
nature.com/articles/s41531-0…
BrentRyanLab retweeted
1/ 🚨 Our new paper is online in @Nature !
As its first author, I’m enthusiastic to finally share it with you all!🎉
🧠 We discovered a mechanistic link between cellular energy metabolism and the control of the need to sleep 💤
👉 nature.com/articles/s41586-0…
@OxfordDPAG 🧵👇
BrentRyanLab retweeted
Abstracts close in 48h for the 11th ISA! isa11.org/
Speaker slots still available including for ECRs and PhD students, as well as poster and speaker prizes!
ABSTRACTS CLOSE 18 July!
The 11th International Symposium on Autophagy 2025
📅 16–20 November 2025 | Lorne, Victoria
Registration: isa11.org/
We have a fantastic line-up of speakers and a wide range of topics focused on the fascinating world of autophagy.
BrentRyanLab retweeted
Excited to see finally see this one in print with all the collaborators from @_neuroproteome. All proteomic data from the publication set and the full consortia (35k samples) also now available on the ADWorkbench nature.com/articles/s41591-0…
BrentRyanLab retweeted
Our thanks to Briana De Miranda @uab_neurology who joined us online today to give a talk to the OPDC on Initiating & persisting mechanisms of #Parkinson’s #neurodegeneration from environmental risk factors. @KavliOxford @OxfordDPAG @BRyanLab2 talks.ox.ac.uk/talks/id/0617…