@BembenekLab

Investigating mechanisms of cell division, especially cytokinesis, during embryonic development.

 Detroit, MI
bembeneklab.org
Joined October 2012
  • Tweets1.6K
  • Following1.6K
  • Followers2.1K
145Media
Bembenek Lab retweeted
J Cell Science@J_Cell_SciOct 7
New JCS snapshot - Outer kinetochore proteins form linear elements to regulate vesicle transport Shane Kowaleski presents the key findings from their recent JCS paper with Joshua Bembenek and team. journals.biologists.com/jcs/…
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Bembenek Lab retweeted
Jomon Joseph@JomonJosephJoeJul 26
Annulate lamellae – an underexplored cellular structure journals.biologists.com/jcs/…

Annulate lamellae – an underexplored cellular structure

Summary: This Review discusses insights into the structure, biogenesis and functional relevance of annulate lamellae – endoplasmic reticulum subdomains harbouring a subset of nucleoporins.

journals.biologists.com
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Bembenek Lab retweeted
kuba sędziński@ksedzinskiMay 19
Basal bodies (BBs) are what eventually become motile cilia. So, if they don't get positioned correctly on the apical surface, the whole tissue level function can go wrong → ciliopathies. We know actin is involved… but how does it actually control this process? 🤔 (3/17)
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Bembenek Lab retweeted
J Cell Science@J_Cell_SciMay 20
Also in Issue 9: - Research Highlights on plasmalogens, tricalbins, protein secretion and cell division - Interview with Noboru Mizushima - A century of cell death research - The Balbiani body at a glance journals.biologists.com/jcs/…
JCS poster – The Balbiani body at a glance

ALT JCS poster – The Balbiani body at a glance

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🚨Please repost!! 🧬We are hiring POSTDOC now!! Fully-funded 5-year position 👩🏻‍🔬👨‍🔬
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Mitotically Driven Cytoskeletal Reorganization Governs Zebrafish Left-Right Organizer Detachment from EVL and Lumen Morphogenesis biorxiv.org/content/10.64898… #biorxiv_cellbio
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Bembenek Lab retweeted
FoxLabNC@FoxLabNCMar 20
My lab is accepting applications for a fully funded postdoctoral fellow position, beginning in 2027. Applicants must clearly articulate specific interests in our lab's research.
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Yang et al show that #Celegans CKS-1 is required, w/ CDK-1, for #anaphase B during oocyte #meiosis I; promotes anaphase onset thru. securin & cyclin B1 destruction in meiosis I & II, respectively; & acts positively w/ both securin & cyclin B3 in meiosis II hubs.la/Q03_WFhj0
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Spotlight: Moghareh, Bojorquez, and Lara-Gonzalez @ucirvine highlight work from Yang et al. (hubs.la/Q03_WPfB0) showing that CKS-1 plays key roles in both #anaphase B during #oocyte #meiosis I and the #metaphase II–to–anaphase II transition. hubs.la/Q03_WP970
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Membrane rupture and independent extension of sister membranes drive cytokinesis in C. elegans embryos biorxiv.org/content/10.1101/…

Membrane rupture and independent extension of sister membranes drive cytokinesis in C. elegans...

Cell division, the physical separation of a cell into two daughter cells, is classically thought to require continuous plasma membrane invagination driven by equatorial contractile forces. Here, we...

biorxiv.org
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How is timely and accurate sister chromatid separation achieved? A process that is happening around 30-50 billion times per minute!!! in the human body needs tight regulation (to avoid cancer development...). paper: lnkd.in/eHCYuyhc comment: lnkd.in/ezyw2dxi
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Bembenek Lab retweeted
Emma Koory@EmmaKoory10 Nov 2025
Been doing a lot of time lapses of iPSC-derived cardiac muscle cells lately! Here's one of my favorites. This cell is expressing fluorescent alpha-actinin-2 and the colors represent depth. Movie length = 24h with frames taken every 20m. #microscopymonday #cellbiology @MAG2ART
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Bembenek Lab retweeted
Tim Stearns@StearnsLab8 Nov 2025
profiles.nlm.nih.gov/1015845…
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Happy Halloween 👻🎃!
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The nuclear localization of Ect2 is required for cytokinesis biorxiv.org/content/10.1101/… #biorxiv_cellbio

The nuclear localization of Ect2 is required for cytokinesis

In cytokinesis, a contractile ring constricts the cell to form two daughters. After ingression, the ring matures into the midbody, and an intercellular bridge connects the daughter cells until it is...

biorxiv.org
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The centriculum, a membrane that surrounds C. elegans centrosomes, acts as a microtubule filter biorxiv.org/content/10.1101/… #biorxiv_cellbio

The centriculum, a membrane that surrounds C. elegans centrosomes, acts as a microtubule filter

Centrosomes are the main microtubule-nucleating structures in dividing cells. They are considered membrane-less organelles, but in several cell types they are surrounded by ER-derived membrane. In C....

biorxiv.org
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John Philip Trinkaus, a student in the 1939 Embryology course, left us with his drawings that show 'presumptive regions' in Trout, Fundulus, Dog fish, and Urodele; development of circulatory system of Teleost; and a squid spermatophore. bit.ly/4eZWxfU
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I’m excited, relieved, and honored to announce that my paper describing non-canonical mitotic mechanisms in the early mouse embryo is out in @ScienceMagazine ! (link at end of 🧵)
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🚨Preprint, RT appreciated🙏 Our work ‘Substrate recognition by human separase’ by @JunYu_unige, Sophia Schmidt, @MargheritaBotto @unige_en @UNIGEnews @MoCel_Geneva @DCI_EM and members from the Morgan @UCSF and @FJ_OReilly labs is online. 🔗biorxiv.org/content/10.1101/…
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Bembenek Lab retweeted
Emmy Delaney@Delanemmy9 May 2025
Henry and Devon’s paper, ‘Phosphate-binding pocket on cyclin B governs CDK substrate phosphorylation and mitotic timing’ is out today in @NatureComms! nature.com/articles/s41467-0…

Phosphate-binding pocket on cyclin B governs CDK substrate phosphorylation and mitotic timing

Nature Communications - Cell cycle control depends on phosphorylation of many proteins by the kinase Cdk1. Here, the authors show that phosphorylation of Cdk1 substrates is influenced by a...

nature.com
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