The Costerton Biofilm Center is a unique interdisciplinary research center established to explore the field of chronic bacterial infections.
Capital Region, Denmark
Joined April 2018
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Costerton Biofilm Center, University of Copenhagen retweeted
Single cells and bacterial #biofilm populations in chronic #wound #infections – New article in APMIS Journal by @MadsLichtenberg, @kirketerp, @Kvichers, Mads Holm Christensen, Blaine Fritz, @tim_jakobsen, @TBjarnsholt-> onlinelibrary.wiley.com/doi/… @wileymicrobio #Bacteriology
ALT Fig. 1. Progressive zoom‐in on large biofilms of Pseudomonas aeruginosa (A–C; patient 13) and Staphylococcus aureus (D–F; Patient 9) found in tissue from patients with chronic leg wounds. P. aeruginosa and S. aureus were stained by species‐specific PNA‐FISH probes, and images were acquired with a slide scanner (A–B, D–E) or by a confocal laser scanning microscope (C, F).
Costerton Biofilm Center, University of Copenhagen retweeted
Chronic wounds are often described as being infected with #biofilms. We have a new paper out demonstrating persisting populations of single cells questioning the dynamics of bacterial persistence patterns in chronic #infections. onlinelibrary.wiley.com/doi/… @BiofilmLab @TBjarnsholt
Costerton Biofilm Center, University of Copenhagen retweeted
Our new review compiles current knowledge on non-attached aggregates, showcasing their presence in nature and disease. A fresh perspective on an old concept! #BiofilmResearch #Microbiology With @KraghBio and T. Tolker-Nielsen in @CommsBio nature.com/articles/s42003-0…
Costerton Biofilm Center, University of Copenhagen retweeted
New publication. It's a methods paper that goes step-by-step into how to carry out the calScreener experiments performed by the group of @TBjarnsholt at @uni_copenhagen
Congrats to @bei_Kat & @MadsLichtenberg for their great work.
eu1.hubs.ly/H03HmFR0
Costerton Biofilm Center, University of Copenhagen retweeted
Full House at the Maersk Tower for the defence of Lasse Kvich…defending an amazing PhD thesis with the topic: bacterial impact on the tumor microenvironment in colorectal cancer @TBjarnsholt @cssdenmark
Costerton Biofilm Center, University of Copenhagen retweeted
Cystisk fibrose-forsker støtter Cystisk Fibrose Foreningen med eget sweater-design | Cystisk Fibrose Foreningen cystiskfibrose.dk/aktuelt/li…
Costerton Biofilm Center, University of Copenhagen retweeted
Changing the starting number of bacteria in #biofilm models result in different phenotypic trajectories governed by different #microenvironments. This influences the susceptibility when treating with #antibiotics. Published in @JournalSpectrum @BiofilmLab journals.asm.org/doi/full/10…
Costerton Biofilm Center, University of Copenhagen retweeted
Excited to see our new paper out in @CellReports. We show that #biofilm formation in #Pseudomonas is associated with high metabolic rates, which are mainly caused by production of biofilm matrix components. @BiofilmLab @UCPH_health and Niels Bohr Institute cell.com/cell-reports/fullte…
Costerton Biofilm Center, University of Copenhagen retweeted
[IN DANISH] See you at Culture Night on Friday? Visit our mini lab with @BiofilmLab to test if you can wash bacteria off your hands - and of course learn more about the largest organ of the body: The skin! @LEOFondet @UCPH_health #kulturnattenkbh
sund.ku.dk/besoeg/kulturnat/
Costerton Biofilm Center, University of Copenhagen retweeted
Thrilled to see that our latest paper from @tbjarnsholt @BiofilmLab has been published in @Jbacteriology. Have a look if you would like to learn how an S. aureus-produced cocktail can ensure coexistence with P. aeruginosa doi.org/10.1128/jb.00174-22 🦠
Costerton Biofilm Center, University of Copenhagen retweeted
Transcription of the Alginate Operon in Pseudomonas aeruginosa Is Regulated by c-di-GMP
@JournalSpectrum from Tim Tolker-Nielsen @BiofilmLab
journals.asm.org/doi/10.1128…
Costerton Biofilm Center, University of Copenhagen retweeted
Transcriptomic Fingerprint of Bacterial Infection in Lower Extremity Ulcers
@APMISJournal by Blaine Fritz et al from @TBjarnsholt @BiofilmLab
"RNA-sequencing (RNA-seq) was performed on biopsies from clinically infected lower extremity ulcers"
onlinelibrary.wiley.com/doi/…
Costerton Biofilm Center, University of Copenhagen retweeted
22 participants listening carefully to the godfather in electrochemical #microsensors Niels Peter Revsbech giving the grand overview at the #microsensor2022 course
Costerton Biofilm Center, University of Copenhagen retweeted
Is increased lactate after intubation an early warning? onlinelibrary.wiley.com/doi/… #lactate #inflammation #infection #intubation #intensivecareunit @KolpenM @BestleMorten @FBHertz @POestrup @WileyBiomedical @Wileymicrobio
ALT Figure 4: Levels of L-lactate correlates with the density of neutrophils in all tracheal aspirates. (A) L-lactate was significantly correlated with the density of neutrophils in the aspirates (p<0.001; rho=0.5093, n=145). (B) No significant correlation was found between D-lactate and neutrophils (P=0.1; rho=-0.1038, n=252). Statistical significance was assessed using Spearman correlation test.
Costerton Biofilm Center, University of Copenhagen retweeted
"Endotracheal lactate reflects lower respiratory tract infections and inflammation in intubated patients". Collab @POestrup @FBHertz @BestleMorten Daniel Faurholt-Jepsen and Christian Dalby Sørensen Jepsen://onlinelibrary.wiley.com/doi/abs/10.1111/apm.13224#.YkbhtTfYUCg.twitter
Costerton Biofilm Center, University of Copenhagen retweeted
Human skin microbiota in health and disease. The cutaneous communities’ interplay in equilibrium and dysbiosis. Review by Lene Bay & Hans Christian Ring -> doi.org/10.1111/apm.13201
@BiofilmLab #chronicwounds #microbiota #microbiology #microbiome @wileymicrobio @WileyBiomedical
Costerton Biofilm Center, University of Copenhagen retweeted
The evolutionary trajectories of P. aeruginosa in biofilm and planktonic growth modes exposed to ciprofloxacin: beyond selection of antibiotic resistance
from Oana Ciofu at @BiofilmLab
w/ @moasommer @Andreas_Porse at @DTUBiosustain
nature.com/articles/s41522-0…
Costerton Biofilm Center, University of Copenhagen retweeted
How do you identify inflammatory cells in tissue from chronic infections? Our new manuscript led by Maria Alhede is a thorough guide, please take a look. Supported by @lundbeckfonden ncbi.nlm.nih.gov/pubmed/3019…
Costerton Biofilm Center, University of Copenhagen retweeted
A nice article about our latest @whiteleylab paper #CF #aggregates #QS cysticfibrosisnewstoday.com/…
Costerton Biofilm Center, University of Copenhagen retweeted
M Khül talking about @TBjarnsholt and @KraghBio on alginate beads as a infection biofilm model - there’s a video for that naturemicrobiologycommunity.… @NatureMicrobiol #Biofilms8 – at Arhus, Denmark