@BoneJointRes

A Gold open access orthopaedics and musculoskeletal research journal edited by Ms Chloe E. H. Scott and published by Bone & Joint. Impact factor: 5.1.

 London, UK
bjr.boneandjoint.org.uk/
Joined May 2012
  • Tweets8.1K
  • Following1.3K
  • Followers19.1K
3.7KMedia
Could tibial cortex transverse transport improve diabetic wound healing by modulating the immune response? 🔎 This week’s episode explores the role of monocytes and macrophages in this process. Listen below! #Podcast #OrthoTwitter #WoundHealing ow.ly/m7vA50ZXxNI
AI Talks with Bone & Joint Research. Tibial cortex transverse transport accelerates diabetic wound healing via systemic mobilization of non-classical monocytes. Article details: Yang et al. Bone Joint Res. 2026;15(8):937-950. Winner of the ALPSP Award for Innovation in Publishing 2025. Image of microscope in background.

ALT AI Talks with Bone & Joint Research. Tibial cortex transverse transport accelerates diabetic wound healing via systemic mobilization of non-classical monocytes. Article details: Yang et al. Bone Joint Res. 2026;15(8):937-950. Winner of the ALPSP Award for Innovation in Publishing 2025. Image of microscope in background.

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This study aimed to reconstruct AORI type III tibial defects using a 3D-printed extension-stem augment, followed by surface-type knee reconstruction to achieve long-term stability and promising clinical outcomes. #Biomechanics #KneeReconstruction #Bone ow.ly/4gWc50ZZS30
Image depicts loads and constraint conditions applied to the tibial fnite element model.

ALT Image depicts loads and constraint conditions applied to the tibial fnite element model.

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This study aimed to evaluate the BioFire Joint Infection Panel in cases of hip & knee periprosthetic joint infection where conventional microbiology is unclear & to assess its role as a complementary intraoperative diagnostic tool. #Infection #Surgeons ow.ly/OwqU50ZY7cQ
Bone & Joint Research. Abstract text for article titled 'The role of BioFire Joint Infection Panel in diagnosing periprosthetic hip and knee joint infections in patients with unclear conventional microbiological results'.

ALT Bone & Joint Research. Abstract text for article titled 'The role of BioFire Joint Infection Panel in diagnosing periprosthetic hip and knee joint infections in patients with unclear conventional microbiological results'.

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Bone & Joint Research retweeted
Bone & Joint@BoneJointPortalOct 22
NEW for Bone & Joint authors! It is now FREE to format your manuscript on Ortho𝘗𝘶𝘣𝘭𝘪𝘴𝘩 for the Bone & Joint journals @BoneJointJ, @BoneJointOpen and @BoneJointRes. #Orthopedics #OrthoTwitter #MedEd orthopublish.org.uk/home
OrthoPublish offers free formatting for papers submitted to Bone & Joint journals BJJ, BJR, and BJO.

ALT OrthoPublish offers free formatting for papers submitted to Bone & Joint journals BJJ, BJR, and BJO.

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A hybrid model combining mechanobiological simulation and machine learning significantly outperforms clinician heuristics and the Leeds-Genoa Non-Union-Index score in predicting nonunion. #MachineLearning #AI #BoneFracture ow.ly/uWxV50ZZQZX
Editor's Pick Bone & Joint Research. Predicting nonunion – a hybrid machine-learning model combining patient factors and mechanobiological simulation features exceeds clinician accuracy. Article details: Armbruster et al. Bone Joint Res. 2026;15(10):1196-1205. Tree of Andry image in background.

ALT Editor's Pick Bone & Joint Research. Predicting nonunion – a hybrid machine-learning model combining patient factors and mechanobiological simulation features exceeds clinician accuracy. Article details: Armbruster et al. Bone Joint Res. 2026;15(10):1196-1205. Tree of Andry image in background.

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Overexpression of baculoviral inhibitor of apoptosis repeat-containing protein 3 enhanced healing of tibial bone defects in mice, suggesting its potential therapeutic application. #Bone #StemCells #Biology ow.ly/oqGf50ZZRxn
Bone & Joint Research. Abstract text for article titled 'BIRC3 facilitates osteogenic differentiation of bone marrow mesenchymal stem cells via NGFR/β-catenin signalling axis'.

ALT Bone & Joint Research. Abstract text for article titled 'BIRC3 facilitates osteogenic differentiation of bone marrow mesenchymal stem cells via NGFR/β-catenin signalling axis'.

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This study indicates that pharmacological modulation of the GH/IGF1 system promotes distinct, sex-specific effects on bone in Pappa2-deficient mice. Check out this paper by Prof Juan Suárez, Professor at @InfoUMA & co-lead researcher at IBIMA. #Research ow.ly/7Mqg50ZZQbj
Author feature, Bone & Joint Research. Headshot image of Juan Suárez. Tree of Andry image in background.

ALT Author feature, Bone & Joint Research. Headshot image of Juan Suárez. Tree of Andry image in background.

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Mini-plate fixation demonstrated superior resistance to bending-induced micromotion compared with dual-screw fixation in distal metatarsal osteotomy. Read last month's most popular #BJR paper now! #Osteotomy #Orthopedics #Bunion ow.ly/TXpv50ZZJTX
Cover of BJR Paper of the Month featuring a study on biomechanical comparison of mini-plate and screw fixation in distal metatarsal osteotomy for hallux valgus.

ALT Cover of BJR Paper of the Month featuring a study on biomechanical comparison of mini-plate and screw fixation in distal metatarsal osteotomy for hallux valgus.

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DNA-damage-inducible transcript 4 regulates pyroptosis of nucleus pulposus cells via the reactive oxygen species-thioredoxin-interacting protein-NLRP3 axis. #Spine #OrthoTwitter #FOAMed ow.ly/WzYI50ZY72A
Bone & Joint Research. Abstract text for article titled 'siRNA incorporated in slow-release injectable hydrogel continuously silences DDIT4 and regulates nucleus pulposus cell pyroptosis through the ROS/TXNIP/NLRP3 axis to alleviate intervertebral disc degeneration'.

ALT Bone & Joint Research. Abstract text for article titled 'siRNA incorporated in slow-release injectable hydrogel continuously silences DDIT4 and regulates nucleus pulposus cell pyroptosis through the ROS/TXNIP/NLRP3 axis to alleviate intervertebral disc degeneration'.

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Knockdown of spermidine/spermine N1-acetyltransferase 1 and arachidonate 15-lipoxygenase can reduce chondrocyte inflammation and ferroptosis. #Osteoarthritis #Inflammation #Research ow.ly/WbBU50ZY6Tc
Bone & Joint Research. Abstract text for article titled 'Inhibition of SAT1 alleviates chondrocyte inflammation and ferroptosis by repressing ALOX15 expression and activating the Nrf2 pathway'.

ALT Bone & Joint Research. Abstract text for article titled 'Inhibition of SAT1 alleviates chondrocyte inflammation and ferroptosis by repressing ALOX15 expression and activating the Nrf2 pathway'.

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Bone & Joint Research retweeted
The Bone & Joint Journal@BoneJointJOct 16
☝️'Select your specialties and let's get going' | ⏰ Quick Start mode on BJJ LIFE Select 'All specialties' or target a specific topic, and we'll keep asking questions until you choose to finish the test. #FRCSExam #Orthopedics #OrthoTrainees ow.ly/6i2t50ZXCWZ
BJJ Life logo with a green leaf and tagline about orthopaedic MCQ resources from The Bone & Joint Journal above a Quickstart button.

ALT BJJ Life logo with a green leaf and tagline about orthopaedic MCQ resources from The Bone & Joint Journal above a Quickstart button.

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The findings of this study support the development of a postoperative periprosthetic femoral fracture-specific core outcome set with a recommended set of feasible outcome measurement instruments. #Fracture #Trauma #OrthoTwitter ow.ly/a6s450ZY6Nw
Bone & Joint Research. Abstract text for article titled 'Reported outcomes for patients following postoperative periprosthetic femoral fractures'.

ALT Bone & Joint Research. Abstract text for article titled 'Reported outcomes for patients following postoperative periprosthetic femoral fractures'.

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These findings have major implications for future therapies for immunomodulation of bone to enhance fracture healing and repair bone defects. #BoneRegeneration #StemCells #Trauma ow.ly/645A50ZXvsB
Diagram depicts crosstalk between mesenchymal stem cells (MSCs) and macrophages.

ALT Diagram depicts crosstalk between mesenchymal stem cells (MSCs) and macrophages.

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The aim of this study is to investigate the effects of senescent osteocytes on bone homeostasis in the progress of age-related osteoporosis and explore the underlying mechanism. #Bone #Biology #Osteoporosis ow.ly/vL7S50ZXweX
Bone & Joint Research. Abstract text for article titled 'Down-expression of miR-494-3p in senescent osteocyte-derived exosomes inhibits osteogenesis and accelerates age-related bone loss via PTEN/PI3K/AKT pathway'.

ALT Bone & Joint Research. Abstract text for article titled 'Down-expression of miR-494-3p in senescent osteocyte-derived exosomes inhibits osteogenesis and accelerates age-related bone loss via PTEN/PI3K/AKT pathway'.

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Patients with generalized joint laxity exhibited significantly higher collagen type III content in the semitendinosus tendon compared to those without. #OrthoTwitter #ACL #Injury #FOAMed ow.ly/HegT50ZXuKM
Image depicts preoperative stress radiographs obtained using the Telos stress device and fuoroscopic image under anaesthesia in a 20-year-old male.

ALT Image depicts preoperative stress radiographs obtained using the Telos stress device and fuoroscopic image under anaesthesia in a 20-year-old male.

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" The main takeaway is that tibial cortex transverse transport enhances diabetic wound healing by mechanically stimulating the bone marrow to mobilize non-classical monocytes". Catch the full findings below! #Podcast #WoundHealing #Research ow.ly/GjQU50ZXHeJ
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We aimed to develop and validate a novel prediction model for osteoporosis based on serotonin, fat-soluble vitamins, and bone turnover markers to improve prediction accuracy of osteoporosis. #Biology #Osteoporosis #Research ow.ly/afxK50ZXvbG
Diagram showing effects of serotonin and fat-soluble vitamins on the pathogenesis of osteoporosis. Interactive communication between serotonin and fat-soluble vitamins (vitamin A, vitamin D3, vitamin E, and vitamin K) is critical for bone health.

ALT Diagram showing effects of serotonin and fat-soluble vitamins on the pathogenesis of osteoporosis. Interactive communication between serotonin and fat-soluble vitamins (vitamin A, vitamin D3, vitamin E, and vitamin K) is critical for bone health.

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Accelerometry provides scalable, objective functional assessment, revealing procedure-specific differences which are not captured by patient-reported outcome measures. #Arthroplasty #PhysicalActivity #Research ow.ly/8jC450ZXule
Bone & Joint Research. Abstract text for article titled 'Accelerometry-based comparison of functional outcomes across total and partial knee and hip arthroplasty'.

ALT Bone & Joint Research. Abstract text for article titled 'Accelerometry-based comparison of functional outcomes across total and partial knee and hip arthroplasty'.

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Fracture-related infections (FRIs) are a major concern for patients and healthcare systems, yet their impact on mental health has been largely overlooked. This study aimed to assess the longitudinal impact of FRI on patients’ quality of life. #Healthcare ow.ly/JzU550ZVt8M
Bone & Joint Research. Abstract text for article titled 'Mental health implications of fracture-related infections'.

ALT Bone & Joint Research. Abstract text for article titled 'Mental health implications of fracture-related infections'.

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" This study shows that PJI & AO can be distinguished by detailed bone histology, with PJI associated with marked degradation & distinct changes in the osteocyte lacunocanalicular network". 🦴 Check out the full discussion below! #AITalks #Infection ow.ly/H8G950ZWlHr
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