@BorisMartinac

Stretch-activated biophysicist, turning slowly into stretch-inactivated one... just kidding! 🤓

 Sydney, Australia
victorchang.edu.au/about-us/our-scientists/prof-boris-martinac
Joined October 2019
  • Tweets214
  • Following270
  • Followers464
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For your information and further consideration about submitting your work for publication in the Collection on "Mechanosensitive and Mechanoregulatory Ion channels", please use the link: lnkd.in/g5zNcRxF. I'll be looking forward to your manuscript submissions.
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npj Biological Physics and Mechanics/ Mechanosensitive and Mechanoregulatory Ion Channels
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Stretch activation of Piezo1 channels doi.org/10.1007/s12551-025-0…

Targeted elimination of mesenchymal-like cancer cells through cyclic stretch activation of Piezo1...

Biophysical Reviews - The application of cyclic stretch could represent a novel therapeutic method for fighting cancer. Research indicates that this mechanical stimulus selectively induces cell...

link.springer.com
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Boris Martinac retweeted
Charles Cox@Charles_D_Cox30 Jan 2025
First pre-print of 2025! Collaborative effort with the Martinac and Feneley labs looking at the long term impact of Piezo1 deletion on cardiac function. Some very cool data, particularly a link between atrial stretch-Piezo1 channels and ANP release!! biorxiv.org/content/10.1101/…

Deletion of PIEZO1 in adult cardiomyocytes accelerates cardiac aging and causes premature death

Mechanosensitive PIEZO1 channels have emerged as key transducers of mechanical forces in the cardiovascular system. In cardiomyocytes, we previously showed that PIEZO1 decodes mechanical cues driving...

biorxiv.org
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South Australia’s renewable triumph is stunning proof that Dutton’s nuclear plans are a folly reneweconomy.com.au/south-au…

South Australia's renewable triumph is stunning proof that Dutton's nuclear plans are a folly

Few people are aware of South Australia's charge towards 100 per cent net renewables, but it is the perfect riposte to the Coalition's nuclear folly and scare campaign.

reneweconomy.com.au
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Boris Martinac retweeted
Charles Cox@Charles_D_Cox10 Jun 2024
A pervasive view is that TRP channels represent primary sensors of mechanical forces. Along with @PooleLab1 and @BorisMartinac we reviewed the evidence supporting this in @TrendsBiochem cell.com/trends/biochemical-…
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We used FluidFM and lifetime fluorescence microscopy (Flipper-TR) to investigate the coupling of force application and tension propagation. Thanks @CapitanioLab for helping with the Optical Tweezers, @BorisMartinac for endless discussions, and everyone else for their contribution
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linkedin.com/notifications/?…

LinkedIn Login, Sign in | LinkedIn

Login to LinkedIn to keep in touch with people you know, share ideas, and build your career.

linkedin.com
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High-content method for mechanosignaling studies using IsoStretcher technology and quantitative Ca2+ imaging applie… pubmed.ncbi.nlm.nih.gov/3848…

High-content method for mechanosignaling studies using IsoStretcher technology and quantitative...

The importance of mechanosensory transduction pathways in cellular signalling has prominently come to focus in the last decade with the discovery of the Piezo ion channel family. Mechanosignaling...

pubmed.ncbi.nlm.nih.gov
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Functional coupling between Piezo1 and TRPM4 influences the electrical activity of HL‐1 atrial myocytes - Guo - The Journal of Physiology - Wiley Online Library physoc.onlinelibrary.wiley.c…

Functional coupling between Piezo1 and TRPM4 influences the electrical activity of HL‐1 atrial...

Abstract figure legend Piezo1–TRPM4 interaction influences the action potential frequency of HL-1 atrial myocytes. Top: Yoda1-evoked Piezo1 activation stimulates TRPM4 via the increase of intracell...

physoc.onlinelibrary.wiley.com
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We also wanted to say a big thanks to all the speakers and attendees for making this a great meeting!! Counting the days to next one #Mechanobiology
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Molecular insights into the force-from-lipids gating of mechanosensiti... sciencedirect.com/science/ar…
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Mechanisms of PIEZO Channel Inactivation mdpi.com/2479994 #mdpiijms via @IJMS_MDPI

Mechanisms of PIEZO Channel Inactivation

PIEZO channels PIEZO1 and PIEZO2 are the newly identified mechanosensitive, non-selective cation channels permeable to Ca2+. In higher vertebrates, PIEZO1 is expressed ubiquitously in most tissues...

mdpi.com
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2023 Meeting of the Australian Society for Mechanobiology - gentle reminder that the deadline for submission of abstracts and applications for student travel awards and the dependent-care grant is Saturday, September 16th. More details 👇👇👇2023mechanobiologymeeting.co…
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Boris Martinac retweeted
Charles Cox@Charles_D_Cox17 Aug 2023
Lots of interesting things to follow; do other molecules bind as part of a mechanosensory complex and does PIEZO1 regulate transcription through MDFI/MDFIC? But for now, a huge thanks to all the contributors and supporters, especially @BorisMartinac !
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Check out this job from Victor Chang Cardiac Research Institute linkedin.com/jobs/view/36764…
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careers-victorchang.lanteria…
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My research is available on @ResearchGate: researchgate.net/publication…

(PDF) A novel force transduction pathway from a tension sensor to the gate in the mechano-gating of...

PDF | The bacterial mechanosensitive channel of large conductance MscL is activated exclusively by increased tension in the membrane bilayer. Despite... | Find, read and cite all the research you...

researchgate.net
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