Cancer researcher, EBM/Clinical Practice Guidelines wizard, Brazilian Jiu-Jitsu Black Belt, husband, father. A 🇨🇦 working in the 🇺🇲. Posts my own.
15 minutes into the future
Joined June 2008
- Tweets1.9K
- Following1.1K
- Followers351
- Likes5.9K
R. Bryan Rumble retweeted
Important clarification from the ASCO Living Guideline for #mCRPC: #PSMA PET positivity is an eligibility criterion for 177Lu-PSMA-617, not a basis to exclude radium-223 or other PSMA-independent therapies.
Full Article here: doi.org/10.1200/JCO-26-01001
📢 New paper out today in European Urology (co-authored)!
🔗 authors.elsevier.com/c/1m-pV…
#Urology #Oncology #MedTwitter #ClinicalResearch
R. Bryan Rumble retweeted
The @ASCO EBMC is in the best of hands! #ASCOGuidelines are the best. @BryanRumble @BrittanyEHarvey @DrN_CancerPCP @tomleblancMD and many more!
@ASCO headquarters this morning for the Evidence Based Meeting Committee Meeting . Ready to work with an amazing group of volunteers creating guidelines for the ever changing landscape of oncology. @BeverlyMoy Dr Eric Roeland
R. Bryan Rumble retweeted
Join me and @Thalcin @adawaksmd @AnaVManana @SWentMD @MGBCI_BreastOnc @MassGenBrigham @DFCI_BreastOnc @UCSFCancer @DukeCancer & many more at Best of ASCO Boston! Registration is free.
Total Health, along with our Program Chairs
Dr. @BeverlyMoy and Dr. @Thalcin, invite you to the 2026 Best of ASCO® Boston conference taking place this summer!
Save your spot today at: totalhealthoncology.com/upco…
#OncologyEducation #FreeCME #TotalHealth
R. Bryan Rumble retweeted
The Updated ASCO Guidelines on Metastatic Castration-Resistant Prostate Cancer - @RohanGarjeMD
@BryanRumble @ASCO
oncodaily.com/url/289209
#Cancer #OncoDaily #Oncology #GlobalAwareness #FightAgainstCancer #CancerWorld #ASCO #mCRPC
R. Bryan Rumble retweeted
NEW: The EAU Guidelines Bot
The right answers, seconds away
Ask personalised treatment questions and receive instant answers based on the EAU Guidelines.
Available in each topic section of the EAU Guidelines.
Try it today via the Guidelines page: uroweb.org/guidelines
One theme from the ASCO 2025 Annual Meeting was AI and how it can used to improve the care patients receive. The ASCO Guidelines Assistant with Google Gemini is now live: Glass.asco.org
R. Bryan Rumble retweeted
🎤 The @ASCO annual meeting is a showstopper—from the main stage to the epic exhibits.
Behind the scenes is the incredible 🌟ASCO STAFF🌟 making it all happen.
I caught up with a few of them!
#ASCO25BTS
#PEOPLEOFASCO25
(PS: BRACE YOURSELF FOR A SPECIAL APPEARANCE!!)⁉️🤯👀
R. Bryan Rumble retweeted
If you're a trainee or early career attending #ASCO25, stop by the Trainee and Early Career Lounge for Panel Talks, Roundtable Sessions, and Networking Events (+ mentoring and refreshments!) @asco asco.org/annual-meeting/netw…
I was a guest on The Strenuous Life Podcast with Stephan Kesting: episode 423: BJJ, Science, and D&D with Bryan Rumble. I had a great time, really enjoyed our conversation, and hope you do too.
pca.st/cg98z4gm
R. Bryan Rumble retweeted
Systemic Therapy in Patients With Metastatic Castration-Resistant Prostate Cancer
@ASCO Guideline Update
ascopubs.org/doi/full/10.120…
The updated ASCO guideline provides evidence-based recommendations for the systemic treatment of patients with metastatic castration-resistant #ProstateCancer (mCRPC). Therapeutic options with demonstrated overall survival benefit include androgen receptor pathway inhibitors (ARPIs), 💊PARP inhibitors, chemotherapy (docetaxel, cabazitaxel), radiopharmaceuticals ☢️(radium-223, 177Lu-PSMA-617), and sipuleucel-T. For patients with BRCA1/2 alterations, ARPI–PARP inhibitor combinations or PARP inhibitor monotherapy are recommended based on prior treatments. Continued androgen-deprivation therapy, early somatic genetic testing, 🦴bone-protective agents for patients with bone metastases, and palliative care are advised. Treatment selection should be guided by prior systemic therapies, although optimal sequencing remains unclear.
@RohanGarjeMD @IrbazRiaz @SyedArsalanN @BryanRumble @TiansterZhang @katy_beckermann @NehaVapiwala @sebastienhotte @arnabguonc @AlanBryce9 @lisabodei @DrAndrewLoblaw @HamidEmamekhoo @thomashopemd @M_Hassan_Murad @hongfangliu
Ping
@Silke_Gillessen @AOmlin
@nataliagandur @bavilima
R. Bryan Rumble retweeted
Avoid FOMO and be part of something bigger! #ASCO25 is where scientific discovery and global connections converge. Secure your spot to discover the biggest oncology research of the year and add your voice to conversations that will transform tomorrow’s outcomes.
Systemic Therapy in Patients With Metastatic Castration-Resistant Prostate Cancer: ASCO Guideline Update now available: ascopubs.org/doi/10.1200/JCO…
R. Bryan Rumble retweeted
Germline and Somatic Genomic Testing for Metastatic
Prostate Cancer: @ASCO Guideline Clinical Insights. #mpc #pcsm
Co-authored by @vedangiri, @BryanRumble, @lu_KevinLuMD et al.
brnw.ch/21wSdzY
Germline and Somatic Genomic Testing for Metastatic Prostate Cancer: ASCO Guideline Clinical Insights published today: ascopubs.org/doi/10.1200/OP-…. Many thanks to Dr. Veda Giri, Dr. Evan Yu, and Dr. Kevin Lu for their leadership on this paper.
Collaborative large language models for automated data extraction in living systematic reviews has been published in @JAMIA_Journal. Thanks to @muhammadalik_ @UmairAyub35 @IrbazRiaz @SyedArsalanN for their leadership on this important paper.
#LLM #LLMs #SystematicReview
R. Bryan Rumble retweeted
4/4: Special thanks to all the collaborators and co-authors for this effort: @UmairAyub35 @SyedArsalanN @zaryab_riaz #AmmadRaina #SZou @hehuan2112 #AmirSaeidi @BasharHasanMD @BryanRumble @dbittermanmd #JeremyWarner @JiaZou4 #AmyeTevaarwerk #KLevantakos @kenlkehl
R. Bryan Rumble retweeted
3/4: This article is accessible to the community at doi.org/10.1093/jamia/ocae32…
