CLSigulinsky (@CSigulinsky) profile picture

Retinal neuroscientist specializing in gap junctions

Joined May 2020
Photo by CLSigulinsky (@CSigulinsky)Photo by CLSigulinsky (@CSigulinsky)Photo by CLSigulinsky (@CSigulinsky)Photo by CLSigulinsky (@CSigulinsky)Photo by CLSigulinsky (@CSigulinsky)Photo by CLSigulinsky (@CSigulinsky)Photo by CLSigulinsky (@CSigulinsky)Photo by CLSigulinsky (@CSigulinsky)Photo by CLSigulinsky (@CSigulinsky)Photo by CLSigulinsky (@CSigulinsky)
Are you interested in #electricalsynapse? We are looking for a postdoc to work on #connexin niche specialization in #retina and brain using #zebrafish genetics in our new lab @UHouston. Vision scientist? Meet me at ARVO next week. Please RT.
CLSigulinsky retweeted
Hello, team #gapjunction! We’re looking for a postdoc to join @HaasLab. We use #patchclamp and opto to map #connexin-coupled networks and unlock the mysteries of the thalamus. Contact info in profile. Friends and fans, please RT.
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📢Last #IGJC Webinar 👉 Wednesday 26 January at 17.00 CET. Zoom➡️us02web.zoom.us/j/8608494173… Youtube ➡️youtu.be/vlvPFWoPkBM Prof. David M. Miller @VanderbiltU, Marina Rodriguez-Candela #INIBIC and @pj_saez @UKEHamburg Don't miss it!🙌🙌
CLSigulinsky retweeted
Happy to share our latest work. @Imbrosci82 developed a tool for the "Automated detection and localization of synaptic vesicles in electron microscopy images" eneuro.org/content/early/202…
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We were just minding our business, but y'all kept asking 'you sure LinCx will work in mammals?' 🙄 So we put the 6th @getneuro back in the game and she rained 🔥. UPDATE: Long-term precision editing of neural circuits IN👏🏾MAMMALS👏🏾...IN👏🏾MAMMALS👏🏾 drops 🎤 biorxiv.org/content/10.1101/…
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Long term precision editing of neural circuits using engineered gap junction hemichannels - ("mamma call him LinCx, Ima call him LinCx") biorxiv.org/cgi/content/shor…
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Congratulations to former @NeuroMDAUTH grad student Alex Vila on publication of the final(?) paper from his PhD thesis. He documents a suite of proteins in horizontal cells that may play a role in signaling to photoreceptors. 1/3 frontiersin.org/article/10.3…
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CLSigulinsky retweeted
Phenomenal work from an amazing scientist @technikatie. Through a reverse genetic screen, Katie discovered a crucial molecular mechanism that ensures astrocytes form proper territories which are coupled to each other via gap junctions. sciencedirect.com/science/ar…
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New paper in @CurrentBiology! We find a new, unexpected blue/S-cone neuron: M2 ipRGCs. Their Blue-ON input challenges coding hypotheses underlying classic color vision models & establishes a new short-wavelength input to non-image-forming vision @jay_neitz cell.com/current-biology/ful…
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CLSigulinsky retweeted
Are you interested in grad school at Lehigh? We're small but savvy @LehighBiology. If you'd like to find out more (or know someone who might be interested), you're invited to our open house on Monday, 11/23. Fee waivers available.
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Please RT: We are seeking to fill a postdoctoral position to study the role of connexin channels in arrhythmias and cardiomyopathies. Experience in biophysics, electrophysiology and/or connexin cell biology is strongly preferred. DM for more information!
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A new window into large-pore channels. Our latest Research News highlighting work (bit.ly/2T8HYgY) by Pablo S. Gaete, Jorge E. Contreras @DrContrexin @Rutgers_NJMS and colleagues: bit.ly/3dBVrYc #CellularPhysiology #MembraneTransport
Beautiful serial EM analysis of the development and remodeling of the midget circuit in the human fovea: in adult, 1 cone is connected to 1 OFF +1 ON bipolar neurons respectively connected to 1 OFF and 1 ON RGC. Rachel Wong @UW @Dacey_Lab disq.us/t/3s399pz
CLSigulinsky retweeted
🗣Here is the final program of Session 3 within @ScienceXpress Registration is still open Flash presentations from @MariaDMayan @ProtoQSAR @Trisha_CxGCU @ataberurbi @TrondAasen @gourdier1 @dr_swayne labs and many others 🤩👇🏻
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I am happy to share our work on calcium-calmodulin regulation of electrical synapses in @IJMS_MDPI. Led by lab alumna Xiaofan Li and current members Jaya Aseervatham and Cheryl Mitchell, with collaborator Ruth Heidelberger. @NeuroMDAUTH @BCBatGSBS. 1/9 mdpi.com/814606
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CLSigulinsky retweeted
Here, the O'Brien lab shows that the calmodulin binding sites of connexin35 make it less sensitive to intracellular calcium than other connexins, opening room for CaMKII and calmodulin to compete in regulating electrical synapse strength. mdpi.com/1422-0067/21/17/634…
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Erik Jorgensen is collaborator in the grant the NSF has awarded @MoranEyeCenter scientist Bryan W. Jones, part of the NeuroNex international consortium. The neuroscientists will explore the connections btwn neurons, known as synapses. bit.ly/32spUmj @uofu_science
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Moran researcher @BWJones joins one of four interdisciplinary teams receiving more than $50 million over five years as part of @NSF National Science Foundation's Next Generation Networks for Neuroscience program, also known as #NeuroNex. healthcare.utah.edu/moran/ne…
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CLSigulinsky retweeted
Researchers @UofUMedicine used high resolution #connectomics to map retinal gap junctions, highlighting the contribution of gap junctions in retinal networks & contributing to understanding of visual processing in healthy & diseased retina. #JNeurosci: jneurosci.org/lookup/DOI/10.…
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CLSigulinsky retweeted
Congratulations to Dr. Jones and all of his collaborators on this important work!
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