Cardiology Now News

LV Unloading Does not Reduce Infarct Size in Anterior MI: STEMI DTU Trial Written by @leahkosyakovsky More summary and analysis from #ACC26 below: cardiologynownews.org/?p=139… @CMichaelGibson @ceciliabahit

Two-Lead CRT-DX System Without Atrial Pacing Non-Inferior to Conventional Three-Lead CRT-D: Results from the CRT-NEXT Trial Written by @nkong_med More summary and analysis from #ACC26 below: cardiologynownews.org/?p=139… @CMichaelGibson @ceciliabahit

AI-Based ECG Screening for Structural Heart Disease Demonstrates Moderate Performance in a Community Setting: Results from the PREVUE-VALVE Study Written by @nkong_med More summary and analysis from #ACC26 below: cardiologynownews.org/?p=139… @CMichaelGibson @ceciliabahit

First-in-Human Gene Therapy for PKP2-Arrhythmogenic Cardiomyopathy Safe and Dose-Dependent PKP2 Protein Restoration: HEROIC-PKP2 Trial Written by @nkong_med More summary and analysis from #ACC26 below: cardiologynownews.org/?p=139… @CMichaelGibson @ceciliabahit

ATTRibute-CM Open-Label Extension: Acoramidis for ATTR-CM Provides Sustained Reductions in Mortality Through 54 months Written by @lucas_marinacci More summary and analysis from #ACC26 below: cardiologynownews.org/?p=139… @CMichaelGibson @ceciliabahit

Dig-RHD: Digoxin Reduces Heart Failure Events in Patients with Rheumatic Heart Disease Written by @lucas_marinacci More summary and analysis from #ACC26 below: cardiologynownews.org/?p=139… @CMichaelGibson @ceciliabahit

TRISCEND II Two-Year Follow-Up: Transcatheter Tricuspid Valve Replacement Demonstrates Durable TR Elimination and Quality-of-Life Improvement Written by @lucas_marinacci More summary and analysis from #ACC26 below: cardiologynownews.org/?p=139… @CMichaelGibson @ceciliabahit

Beta-Blocker Discontinuation Non-inferior to Continuation in Stable Patients After MI: SMART-DECISION Trial Written by @acastrom91 More summary and analysis from #ACC26 below: cardiologynownews.org/?p=139… @CMichaelGibson @ceciliabahit

OCT+CMR Combined Identify Underlying Cause in Majority of MINOCA Cases, No Sex Differences in Mechanisms: The HARP-MINOCA study Written by @GillBasir More summary and analysis from #ACC26 below: cardiologynownews.org/?p=139… @CMichaelGibson @ceciliabahit

Prehospital Heparin Improves Coronary Patency in STEMI Without Excess Bleeding: UFH-STEMI Trial Written by @GillBasir More summary and analysis from #ACC26 below: cardiologynownews.org/?p=139… @CMichaelGibson @ceciliabahit

NT-proBNP-Based Screening Identifies Undiagnosed Heart Failure in Patients with Diabetes: The TARTAN-HF Trial Written by @GillBasir More summary and analysis from #ACC26 below: cardiologynownews.org/?p=139… @CMichaelGibson @ceciliabahit

Tirzepatide Reduces Cardiorenal Outcomes vs Dulaglutide in Patients with Diabetes and CV Disease: SURPASS-CVOT Post Hoc Analysis Written by @GillBasir More summary and analysis from #ACC26 below: cardiologynownews.org/?p=139… @CMichaelGibson @ceciliabahit

IVUS- guided PCI Reduces One-Year Target Vessel Failure vs Angiography -guided PCI in Complex Bifurcation PCI: DKCRUSH VIII Trial Written by @GillBasir More summary and analysis from #ACC26 below: cardiologynownews.org/?p=139… @CMichaelGibson @ceciliabahit

IVUS-guided PCI was Not Associated with Lower Risk of Target-Vessel Failure vs Angiography-guided PCI alone in Complex High-Risk PCI: IVUS-CHIP Trial Written by @GillBasir More summary and analysis from #ACC26 below: cardiologynownews.org/?p=139… @CMichaelGibson @ceciliabahit

Oral NLRP3 Inhibitor, Parunoflast, Reduces Inflammation Alone and in Combination with Semaglutide in Phase 2a Trial Written by Jessie Fox, PharmD More summary and analysis from #ACC26 below: cardiologynownews.org/?p=139… @CMichaelGibson @ceciliabahit

LX2006 Gene Therapy Shows Early Signals of Cardiac Benefit in Friedreich Ataxia Cardiomyopathy Written by @adam_dr_ More summary and analysis from #ACC26 below: cardiologynownews.org/?p=139… @CMichaelGibson @ceciliabahit

Next-generation Cardiac Myosin Inhibitor- BHB/HRS-1893- Promising in Reducing LVOT Gradient in Obstructive HCM: Phase 2 Results Written by @adam_dr_ More summary and analysis from #ACC26 below: cardiologynownews.org/?p=139… @CMichaelGibson @ceciliabahit

Anti-fibrotic Therapy After TAVI Improved Myocardial Fibrosis Regression and Quality of Life: Reduce-MFA Trial Written by @adam_dr_ More summary and analysis from #ACC26 below: cardiologynownews.org/?p=139… @CMichaelGibson @ceciliabahit

NPR1 Agonist XXB750 Fails to Improve Cardiac Biomarkers and Increases Heart Failure Events in Phase 2 Trial Written by @adam_dr_ More summary and analysis from #ACC26 below: cardiologynownews.org/?p=139… @CMichaelGibson @ceciliabahit

CORALreef Add-on Shows Oral Enlicitide Lowered LDL-C More Than Guideline Recommended Oral Non-Statin Comparators Written by @acastrom91 More summary and analysis from #ACC26 below: cardiologynownews.org/?p=139… @CMichaelGibson @ceciliabahit