Determined to understand how tissue regeneration works, by utilising single cell and spatial transcriptomic methods. Currently as Postdoc in Dominic Grün group.
Würzburg, Germany
Joined January 2022
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- Following284
- Followers115
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Andy Chan retweeted
Engineered CAR-monocytes coordinate fibrosis clearance and cardiac regeneration following myocardial infarction dlvr.it/TSt6CV
Andy Chan retweeted
We are excited to share our latest work, in which we used human PSCs to build human “biological pacemaker” organoids that model the structure and function of the sinoatrial node. This provides a new platform to study pacemaker development, disease mechanisms and drug testing.
Online Now! Human PSC-derived sinoatrial node-cardiac plexus assembloids model innervation-associated maturation of pacemaker systems dlvr.it/TSYZR1 #stemcells
Andy Chan retweeted
The EMBO Regeneration Meeting is coming up this September! Don't miss the upcoming registration deadline: May 20. Program and registration: meetings.embo.org/event/26-t…. #EMBORegeneration2026.
ALT Conference Poster for the 2026 EMBO Regeneration meeting
Andy Chan retweeted
Our study on rare immune cell networks in liver cholangitis is now online! Using single-cell and spatial omics to investigate portal immune cell dynamics, we discovered a triad of cholangiocytes, dendritic cells and gdT cells regulating disease response.
rdcu.be/fc60M
Andy Chan retweeted
Primitive macrophages enable long-term vascularization of human heart-on-a-chip platforms
hubs.li/Q049ypY80
Article highlight from Cell Stem Cell
@bme_uoft
Andy Chan retweeted
Happy 30th birthday, Pokémon! Since 1996, the Japanese media sensation has inspired generations of researchers in fields as diverse as evolution, biodiversity and research integrity. go.nature.com/4tZOzKY
Andy Chan retweeted
embl.org/about/info/course-a… The 2nd edition of the upcoming „The NewCardioBiology“, where cardioscientists meet vascular biologists and engineers, has still a limited number of poster presentation positions available. Submit and register until Jan 5th. Please, repost this!
Andy Chan retweeted
Injury-induced Clusterin+ cardiomyocytes suppress inflammation and promote regeneration in neonatal and adult hearts by reprogramming macrophages dlvr.it/TPdgPM
Andy Chan retweeted
🦣🧬🦣 🤯💥 We are pleased to share our new paper about ancient RNA expression profiles from the Woolly Mammoth, now published in Cell @CellPressNews
cell.com/cell/fulltext/S0092…
If you want to know more, read the 🧵 below:
#mammoth #RNA #DNA #Pleistocene
Andy Chan retweeted
Research | Chan et al. generate a high-resolution spatiotemporal atlas of healing hearts and reveal cellular networks of lesion repair, including macrophage-fibroblast interactions that control late-stage fibrosis.
doi.org/10.1038/s44161-025-0…
rdcu.be/ePzs6
Excited to share our new paper “Spatiotemporal dynamics of the cardioimmune niche during lesion repair” just published in Nature Cardiovascular Research!
nature.com/articles/s44161-0…
This massive project was led by my excellent postdoc @ChanAndyson. This work would not have been possible without all our fantastic collaborators, in particular the groups of Peter Kohl and Franziska Schneider-Warme who provided essential experimental in vivo methods.
We also built an Shinyapp interface that allows everyone to access our single cell and spatial datasets easily:
wuesi.medizin.uni-wuerzburg.…
We envision our datasets will serve as a resource will provide insights for the cardiac and regeneration/fibrosis fields in the future!
Huge thanks to my PI Dominic @dominic_grun , my friends/colleagues in the lab, and all my collaborators who shared their efforts and dedication over these years!! This 5 year-journey wouldn’t have been successful
without you all! 🙏
Andy Chan retweeted
Online Now! Human heart-macrophage assembloids mimic immune-cardiac interactions and enable arrhythmia disease modeling dlvr.it/TNvxMR #stemcells
Andy Chan retweeted
Potato evolved from tomato 9 million years ago. cell.com/cell/fulltext/S0092…
@NHM_London Sandra Knapp
@UBC Loren H. Rieseberg
@SCUCN Jianquan Liu
#CAAS Sanwen Huang
@cellcellpress
Andy Chan retweeted
New preprint from the lab! Using multiplexed spatial analysis and single-cell multiomics, we resolved the portal liver immune niche and identified crosstalk between cholangiocytes, dendritic cells and gdT cells controlling fibrosis in a cholangitis model.
biorxiv.org/content/10.1101/…
Andy Chan retweeted
This is effectively a cure for type 1 diabetes. Autologous, (chemically) reprogrammed iPSCs were engineered from a patient's fat cells and injected back into her stomach. After ~2.5 months, she no longer needed insulin and now enjoys ice cream + candy like a normal person.
Andy Chan retweeted
BREAKING: MIT just completed the first brain scan study of ChatGPT users & the results are terrifying.
Turns out, AI isn't making us more productive. It's making us cognitively bankrupt.
Here's what 4 months of data revealed:
(hint: we've been measuring productivity all wrong)
Andy Chan retweeted
My lab at @WeizmannScience was completely demolished by the Iranian missile a few days ago. This is hard and sad as nothing was left to save. We study heart regeneration and regenerative medicine. As such, we will regenerate, regrow and rebuild. The one thing that wasn't gone is our motivation said one of my student. It is true. Here, I would like to thank many of my friends around the globe that offer their help, space and support. I really appreciate that.
