CTO and cofounder @ParseBio. Co-developer of single cell combinatorial barcoding method SPLiT-seq. Making genomics more scalable, flexible, and accessible.
Seattle, WA
Joined October 2016
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- Following845
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Charlie Roco retweeted
So excited to work with @ParseBio to share my work studying the role of Sox9 in promoting branching morphogenesis in mouse intrahepatic bile ducts (IHBDs).
I will highlight how Parse scRNA-seq enabled discovery of a target to rescue IHBD branching in mice lacking Sox9.
Hannah Hrncir of @graczlab – Emory shares her recent work on the genetic controls of biliary duct formation. The pictures of these complex branching structures will amaze you, they’re beautiful.
Virtual Live Webinar: May 1, 9:00 AM PST
resources.parsebiosciences.c…
Charlie Roco retweeted
Are you attending #ASHG23? Don't miss our featured education session with Rahul Satija (@satijalab) from the New York Genome Center. Lunch will be provided for the first 50 attendees.
Charlie Roco retweeted
📣 "Single cell sequencing using Evercode shows a superior outcome compared to 10x Genomics™"
Watch the full video here 👉 parse.bio/3LOcdFA
#comparisonstudy #research #singlecell
Charlie Roco retweeted
Happy to present our new preprint! We ran a head-to-head comparison of sample multiplexing reagents for single-cell RNA-Seq on the same samples on the same day. 1/9 biorxiv.org/content/10.1101/…
Charlie Roco retweeted
That was nuclei extraction extraction, using @S2Genomics singulator and fixation w/ @ParseBio kits (lucky 13 kits!). Looking forward to the next steps 👩🏻🔬
And how was your week? #postdoclife #biology
Charlie Roco retweeted
1/ We previously generated a 1M cell scRNA-seq dataset with 24 Type1 Diabetes/Control PBMC samples. Now Daniel Diaz, one of our Bioinformatics Application Scientists, has built a tutorial showing how you can easily analyze this dataset using existing single cell tools.
Charlie Roco retweeted
You can now do a deep dive into our 1 million cell T1D dataset! It was generated from 24 samples fixed over the span of 3 weeks and barcoded all together in a single run. The donor data was integrated with Harmony to generate the UMAPs. #singlecell hubs.la/Q01gTVjX0
Charlie Roco retweeted
FYI this vignette has now been updated with some of our more recent recommendations for handling SPLiT-seq/ParseBio data with {alevin-fry}. Namely: it's important to quantify in U+S+A mode with a splici reference, and properly import all those counts into R with {fishpond}
Happy to share a little side effort in collaboration with @gshrma_ @nomad421: you can now analyze SPLiT-seq (or @ParseBio) scRNA-seq data using alevin-fry!
combine-lab.github.io/alevin…
Charlie Roco retweeted
We had a blast helping to teach a course on #SingleCell profiling and analysis in #neuroscience to the next generation of researchers with #Cajal! The future of single cell is bright! @cgfbordeaux @Neuro_Bordeaux @HjerlingLeffler @Cajal_Training @AMunozManchado @KharchenkoLab
Charlie Roco retweeted
🎙️@KharchenkoLab & @ParseBio will give their talks as part of our #Cajal course on Single #cell profiling and analysis in #neuroscience
📍@cgfbordeaux
🎟️Free entry
@Neuro_Bordeaux @HjerlingLeffler @Cajal_Training
@KharchenkoLab @AMunozManchado
Charlie Roco retweeted
First mega kit through @ParseBio and the sub library looks great after sequencing! So convenient to run sub libraries and know what’s going on before the big run. Estimating close to 900k cells for this exp!! Looking forward to the final results but so far so good.🤞🏼
Charlie Roco retweeted
Parse Biosciences Roadshow - Single Cell 3.0 Scaled & Simplified, Adelaide Tickets, Tue 21/06/2022 at 10:00 am | Eventbrite eventbrite.com/e/parse-biosc…
Charlie Roco retweeted
Happy Holidays from all of us at Parse Biosciences! We wish you all a joyful holiday season, and may the new year bring boundless promise.
Charlie Roco retweeted
Delighted to share that I’m opening a lab at Seattle’s Institute for Systems Biology @isbsci in January 2022! We will study gene expression in bacterial systems with microbial single-cell transcriptomics. We are looking for a research assistant and a postdoc!
Charlie Roco retweeted
Made an espresso tonic with the @ParseBio caffeine fixation kit before getting back to analyzing my latest SPLiT-seq project ☕ 🧠
Charlie Roco retweeted
We are thrilled to introduce our newest Parse Biosciences Kit: The Caffeine Fixation Kit! Now included in every purchase of a WTK, our Caffeine Fixation Kit allows you to create a perfect cup of local Seattle coffee (and be sure to follow the protocol!).
Charlie Roco retweeted
Congratulations to Dr. Kevin Leclerc from the #leuchtlab, winner of the NYU Langone Core Grant Program Award! Using a Parse Single Cell kit, Dr. Leclerc is uncovering pioneer factors that govern skeletal stem cell reprogramming. @philippleuchtMD @streetscaper
Charlie Roco retweeted
We’re thrilled to announce our partnership with @LGMartelotto's Single Cell Core to bring the Single Cell Whole Transcriptome Core Grant Program to @Harvard! Join us Wednesday (5/26) at 2pm ET to hear more about the program!
parsebiosciences.com/harvard…