Student at the University of Pittsburgh majoring in Biochemistry. Pursuing virology to advance our understanding of pathogens and ways to eliminate them.🦠🔬
Pennsylvania, USA
Joined May 2020
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I'd also like to add to this that there arises a grave issue when those who are pandering to a specific demographic warp their beliefs in the name of influence, power or financial gain. Yet again it is analogous to the Purdue incident. Scientists do their research, the research gets debunked, the companies or politicians then ignore the new research (which is a flaw of the scientific method) if it vaguely disagrees with the agenda or drug they are pushing. We've seen this with vaccines, specifically the MMR scandal regarding autism in vaccines which was found to have contained fabricated statistics, was done on an incredibly small cherry picked sample size and whose results have not been reproducible to this day (though many still actively try to prove this association). The amount of roadblocks and cross checking within scientific research is fierce and in all honesty those in the field are pushed equally hard to disprove past findings as they are to pursue new ones. The whole system is built on a consistent fact-checking basis and the entire system HAS to abide by this scientific methodology. When it was first theorized that H. Pylori was the causative agent of stomach ulcers the widely held scientific belief was that bacteria could not even survive in the pH of stomach acid, yet the theory was proven true when time and time again scientists tried to disprove the H. Pylori hypothesis and failed to disprove it time and time again. This research, which yet again was published, was in part met with major backlash by insurance companies, politicians, and pharmaceutical corporations since the existing treatment protocols were financially lucrative for the medical and pharmaceutical industries. Pharmaceutical companies sold billions of dollars in antacid and acid-suppressing drugs, like Tagamet, which treated the symptoms but not the root cause. Insurance companies profited off of partial gastrectomies to treat ulcers, a profitable procedure that would be rendered unnecessary if a simple antibiotic cure were available. Therapists and psychiatric companies, as well as insurance companies profited off of stress treatments since it was said "stress" caused stomach ulcers. In order to finally settle the science, Barry Marshall literally drank a culture of H. pylori to prove it would cause gastritis, which it did, and then treated himself with antibiotics.
Conclusions within the scientific community are not reached through one study or through one individual, they are CONSTANTLY belittled, challenged and tested. The science becomes settled whenever every possible attempt to disprove a finding cannot do so and no amount of narrative twisting by those who are not within scientific research communities stands a chance at distorting the results of the research. It's so frustrating how researchers simply do their jobs and then get their findings twisted out the mouths of corrupt CEOs and politicians and the public backlash focuses on the scientists themselves. Experts are experts for a reason, and if anyone in the scientific community does take bribes or unknowingly prescribe dangerous things it's doctors, who are trained to look at research but more so are constantly briefed by pharma companies on drugs they're selling who typically don't look any further into the matter than the statistics displayed to them by the seller of the drug themselves. Doctors play NO PART in actually DOING the research or scientific discovery and are simply trained on what discovered things are available to treat their patients. Research is a whole different field of medical science. Researchers cannot treat patients but can get data from treated patients and doctors cannot do research besides helping administer clinical trials. Modern science is so fucked because it's not the science that's at fault it's the people who oversee the science and the people who profit from it.
That's why there are conflict of interest statements in research papers and is also why we laid the legislative hammer down on pharma companies after what Purdue did- Purdue Pharma intentionally misused a single-paragraph letter published in a 1980 edition of the New England Journal of Medicine. The letter, from authors Hershel Jick and Jane Porter, observed a low rate of addiction in a group of closely monitored hospitalized patients who were taking opioids. Purdue's marketing materials then twisted this limited finding into the blanket claim that the risk of addiction was "much less than 1%" for all prescription opioid patients, including those with chronic pain. The company was aware of internal research by Lawrence Robbins et al that found addictive behavior in 8% to 13% of OxyContin patients. Rather than pursuing the concerning nature of these findings, Purdue pushed the ≤1% narrative using the flawed Jick and Porter study; internal documents from 1996 revealed Purdue knew about widespread abuse of OxyContin, the company did nothing to address the issue. The issue yet again, was never the scientists, the scientists knew about the 8-13% statistic. The issue once again was the business aspect, the company and its representatives- who were trained to tell doctors that signs of addiction, such as requests for early refills, were actually signs that the patient's pain was not being treated effectively. They were taught about the fabricated concept of "pseudoaddiction" to encourage doctors to prescribe even higher doses. Purdue also aggressively targeted doctors with meals and gifts, while tracking their prescription habits (which is now illegal). The company often targeted high-prescribing physicians, even those with known histories of improper prescribing (which is now illegal but still occurs) incentivized sales representatives with high commission and fired those who questioned their narrative. They also sent representatives to areas "with high rates of pain" although these yet again were just vulnerable communities like the poor (miners, laborers, etc) the sick or the old. The sales representatives for the most part were doing their job marketing a drug they had been convinced was a solution. Those who held the fault were the higher ups in the company who silenced published studies disagreeing with their claims and brainwashed their sales representatives. The Purdue Scandal is absolutely perfect at capturing what's wrong with modern science and it is NOT the scientists, who were doing valid research and publishing papers warning about Oxycontin. The 1% statistic wasn't even funded by Purdue, it was a small unreliable study done with a tiny sample size on an observed population that was warped by a company. The writer of the "Letter to the Editor" actually ended up suing the company if I recall and deeply regretted publishing it in a paper. Yet again, he was simply doing research, every scientist was doing research and publishing their findings. The key aspect is that science builds and concept proofs nearly constantly and when that 1% statistic was debunked it was no longer in the hands of the scientists, they'd done their job, it was in the hands of politicians, who were lobbied by Purdue. Research is always accurate, interpretations and spins of the research are not. You cannot blame anything within STEM for the actions of corrupt politicians or greedy multinational pharma corporations. There are an insane amount of stage III clinical trials which fail and it's partly due to the much, much heavier restrictions put onto scientific research after the Purdue incident and subsequent opioid crisis. If anything due to that science is more transparent than ever, people just will be people and trust "experts" without medical degrees who say what they will say about data that they cannot even begin to comprehend. Truth is truth coming from an unbiased expert, no one going to law or business can be an expert in medicine.
We're making improvements. They said I couldn't house succulents next to carnivorous plants. They were wrong.
Final buoy extrapolations on Champi. I have concluded that there is only a 5.5% chance that Champi's MSLP at peak intensity was ≥895mb. Attached below is GitHub for files/data/pipeline used and archived versions of models and prior findings.
github.com/evanchiefer/Typho…
15 years later and I finally think of "1, 2, 3, 4 I think I'll have some more" as a comeback to those fucks who made me stop drinking from the water fountain before my thirst was quenched
Evan Chiefer retweeted
Scary visual from Chennai in morning
where the cyclone Arnab 🌪️
🌪️ Cyclone Arnab is bringing terrifying winds of up to 150 km/h! Nature’s fury is on full display as powerful winds threaten everything in their path.
Stay alert and stay safe! 🙏🌊
@grok is this true or not?
They're calling it the most category 2 storm ever
#WATCH | Andhra Pradesh: Very strong winds and heavy rainfall in Amalapuram in Konaseema district as an impact of Cyclone Arnab.
(Video Source: Andhra Pradesh I&PR)
Evan Chiefer retweeted
Due to Cyclone Arnab Storm Surge effect in Ennore North Chennai #CycloneArnab
Evan Chiefer retweeted
Radar loop of Cyclone Arnab going through a second ERC. The new eye has formed partially.
And then they clicked post....
Every single satellite estimate is showing a vmax average 35-37kts higher than their peak forecast in the period.
The very severe cyclonic storm “Arnab” [Pronunciation :Ornab] over Westcentral Bay of Bengal moved west-northwestwards with a speed of 18 kmph during past 6 hours, and lay centered at 0900 UTC of today, the 27th October, 2026 over the same region near latitude 16.2°N and longitude 83.3°E, about 140 km southeast of Kakinada (43189, Andhra Pradesh), 170 km south of Vishakhapatnam (43149, Andhra Pradesh), 230 km east of Machilipatnam (43185, Andhra Pradesh), 300 km east-northeast of Bapatla (43220, Andhra Pradesh), and 380 km south-southwest of Gopalpur (43049, Odisha).
It is very likely to move nearly west-northwestwards during next few hours, then northwestwards and cross Andhra Pradesh & Yanam coasts between Bapatla and Visakhapatnam, close to south of Yanam as a very severe cyclonic storm with the maximum sustained wind speed of 125-135 kmph gusting to 150 kmph by 0600 UTC of 28th October, 2026.
The system is under continuous surveillance of the Doppler Weather Radar at Vishakhapatnam and Machillipatnam.
Still working on the Champi buoy analysis. Really trying to push this data to its limits. Regardless, further revision drops pressure slightly. Reiterating my prior point, Champi at peak intensity was very likely ≤890mb. Our now primary constraining factor for precision is radius of maximum wind, since buoy data did not measure 1min wind speed it has to be assumed. Seeing as you guys like this niche reanalysis of in situ measurements, I'll probably keep them coming. I still have a few kinks to work out here that might push pressure up 1 or 2mb from the current average (working on refining center position accuracy by 0.1-0.2km), but this is pretty close to as far as I can go with the data available. When I do finally manage to get a variant with just a teensy bit more precision, I'll make one more post about this and link the GitHub. Been busy lately, so it might take a few days.
Arnab absolutely bombing out. JTWC is calling it 90kt. They appear to be calling it "the most category 2 category 2 cyclone ever"
They didn't identify shit. As a matter of fact, if you actually read the "study" it's essentially a literature review. They proposed mechanisms that remain unproven based on very sparse data points and even had to include the fact that nothing to date actually supports their hypothesis. Lmfao.
BREAKING: New Paper Reveals How mRNA Vaccine Materials Could Spread From Vaccinated to Unvaccinated People
We identified two distinct forms of mRNA vaccine shedding: internal transcriptional spread and potential human-to-human transfer. Vaccine spreads internally and potentially externally to others. @NicHulscher @Docjohnc @McCulloughFund @neo7bioscience open.substack.com/pub/peterm…
The vaccines are responsible for people not following the first come first serve right of way at four-way intersection stop signs
Brian who now?
Anthropic has filed an S-1 registration statement with the SEC related to its proposed IPO.
Read more: anthropic.com/news/s1-sec
Legal disclaimer: A registration statement relating to these securities has been filed with the SEC but has not yet become effective. These securities may not be sold, nor may offers to buy be accepted, prior to the time the registration statement becomes effective. This post does not constitute an offer to sell or the solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.
