Ofir Cohn retweeted
Happy to share the preprints of two complimentary studies from my Postdoc with @bloodgenes:
We set out to understand the mechanisms underlying inherited childhood B cell lymphoblastic leukemia (B-ALL):
biorxiv.org/content/10.64898…
biorxiv.org/content/10.64898…
Ofir Cohn retweeted
🩸🧬 Dendritic cells are rare but key players in immunity. In a new preprint led by @CohnOfir, we generate a single-cell multi-omic atlas of human dendritic cell differentiation to reveal links to immune-mediated disease: biorxiv.org/content/10.64898…
Decades of research have revealed the intricacies of how dendritic cells (DCs) function, but fundamental questions remain about how this group of cells develops in humans and how this process goes awry in disease. A thread on our new work! (1/9)
biorxiv.org/content/10.64898…
Together, this study defines a key and underappreciated role of human DCs in mediating the consequences of inherited genetic variation on a range of complex disorders. (9/9).
Huge thanks to my mentor @bloodgenes and to all involved in this study! @ALNeehus @lrbzldz @guo_chunjie @chenweng1991 @laila_b_norford
Our paper is finally out! in @CellSystemsCP
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Happy to share our recent study investigating the transcriptional landscape of the host when antecedent influenza infection followed by secondary Streptococcus pneumonia infection.
#Influenza #streptococcus #superinfection
biorxiv.org/content/10.1101/…
We are very excited to share our new preprint now on #bioRxiv:
Distinct gene programs underpinning 'disease tolerance' and 'resistance' in influenza virus infection biorxiv.org/content/10.1101/…
@vikslab
