Computational Medicine Center, Sidney Kimmel Medical College of Thomas Jefferson University
Philadelphia, PA
Joined June 2015
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New Master's in Computational Biology and Medicine
Do you want to learn how to make #biomedical data reveal its secrets? Then, this new program is for you: jefferson.edu/academics/coll…
@JeffersonUniv @KimmelCancerCtr @JeffersonAlumni @TJUHospital
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Do you want to build tools that help scientists make sense of biomedical #data and are used daily by people worldwide? If this appeals to you and you are a #SoftwareDeveloper, join our team at @JeffersonUniv!
cm.jefferson.edu/employment-…
#recruiting #hiring #computationalmedicine
CompMedicineTJU retweeted
New #JeffersonResearch alert! 🚨 How do cells keep “jumping genes” from taking over the #genome? PiRNAs help. The new work in @NatureComms by Dr. @yohei_kirino's lab shows where these tiny regulators come from: nature.com/articles/s41467-0…
@CompMedicineTJU @JeffersonUniv
#RepetitiveElements strike back. Links between #ALU, #SINE, #LINE, #pyknons and human and mouse genes that are prevalent in the #zygote and the #blastocyst.
Read more here cm.jefferson.edu/repetitive-…
@JeffersonUniv @KimmelCancerCtr @JeffersonAlumni
By combining single-cell sequencing with our recently published machine learning techniques, we identified the fruit fly and zebrafish genes that carry the most information about cell 3D structure.
cm.jefferson.edu/cmcs-machin…
@DR_E_A_M
#MachineLearning #ComputationalThinking
Did you know that tRNA fragments contribute to the immune response pathway? Read all about our new findings
on how 5'-tRNA HisGUG halves activate Toll-Like receptor 7 (TLR7)
at cm.jefferson.edu/trna-halves…
@KamleshGaneshP1, @yohei_kirino
#tRF #computationalmedicine
2-day virtual conference on #HealthDisparities
Only 10 days left before patient advocates and scientific leaders from several Academic Centers come together to discuss how to tackle this problem.
You can attend this event for free. Register here: jefferson.zoom.us/webinar/re…
FYI — We will be hosting a two-day symposium on "Big Data, Disease Disparities, and Precision Medicine" (September 08 and 09).
Symposium Program: cm.jefferson.edu/big-data-se…
Registration/Attendance is *free*: jefferson.zoom.us/webinar/re…
#HealthDisparities #PrecisionMedicine #BigData
Did you wonder whether human #microRNA could be targeting transcripts of #SARS_CoV_2 ?
Phillipe Loher from @CompMedicineTJU just made available such an analysis. You can read about it in more detail here: cm.jefferson.edu/coronavirus…
@JeffersonUniv @KimmelCancerCtr @JeffersonAlumni
… and there is a brilliant video made by Tess Cherlin (@alldayscientess) that puts rRNA-derived fragments (rRFs) in the bigger context.
And don't miss the amazing illustrated video first author Tess Cherlin (@alldayscientess) created! 🖍🎥🎨
Watch the full video 👉youtu.be/KarpR35NSIM
#miRNA @RNASociety #scicomm #sciart @SciSketch
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ICYMI: Yet another class of short RNAs (rRNA-derived fragments or rRFs) whose identities and abundances depend on personal attributes. Exciting new regulatory connections await discovery.
A new study published in @BMCBiology from Dr. Isidore Rigoutsos’ lab (@IRigoutsos) at @CompMedicineTJU shows that a new class of #noncoding #RNA depends on a person's genetic ancestry ⚧️ 🌏🧬
Read more about this exciting #JeffersonResearch on The Nexus
nexus.jefferson.edu/science-…
Short RNAs are all the rage… In our review (sciencedirect.com/science/ar…) we discuss what #microRNA isoforms (#isomiRs), tRNA-derived fragments (#tRFs), and #piRNAs mean for #precisionmedicine and #healthdisparities.
@JeffInnovation @JeffersonAlumni @KimmelCancerCtr @JeffersonUniv
MicroRNA isoforms (#isomiRs), tRNA-derived fragments (#tRFs), #metastasis, patient #survival, and #uveal #melanoma. Our latest article, onlinelibrary.wiley.com/doi/…, discusses these connections.
We just deployed our newly redesigned website. Visit cm.jefferson.edu to learn to learn more about what we have been doing.
#computationalmedicine #precisionmedicine #bigdata #tRNAs #miRNAs #piRNAs @JeffInnovation @JeffersonAlumni @KimmelCancerCtr @JeffersonUniv
The Human Genome Project and The Cancer Genome Atlas keep on propelling us forward…
#TCGA @genome_gov @NCI @NIMHD @NCIResearchCtr @NIGMS @NHGRI
New #JeffersonResearch shows the mitochondrial genome may play a significant role in these fragment interactions with cancer. The study led by @IRigoutsos, Director @CompMedicineTJU, challenges our understanding of how genes are controlled. (📰: bit.ly/2Iw2XXQ)
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#tRNAfragments, the #mitochondrion, #cancer, #repeatelements (#junkDNA), and #disparities -- seemingly unrelated yet deeply connected as we show in our latest work: cancerres.aacrjournals.org/c…
Congratulations to the #computationalmedicine team at #Jefferson. Go #PrecisionMedicine!
CompMedicineTJU retweeted
🗞️ In the news: "Getting the answers to what causes some people to develop diseases and not others is driving the groundbreaking medical research being conducted by the Computational Medicine Center at Thomas Jefferson University in Philadelphia." bit.ly/2GrALEr
Terrific leaders. Great initiative.
To improve healthcare-related technology solutions around the world, Jefferson has partnered on an international project where four Israeli companies will receive a total of $1 million toward research & development from the Israel Innovation Authority. bit.ly/2SE97uw
#RedefiningHumanlyPossible: #PrecisionMedicine in the era of #BigData. Learn more about the @CompMedicineTJU team's story at ibm.com/downloads/cas/ZBXXNG… Join the journey at cm.jefferson.edu/
@JeffInnovation @JeffersonAlumni @KimmelCancerCtr @PhiladelphiaU @JeffersonUniv
@CompMedicineTJU's new paper shows links btw regulatory molecules (#isomiRs,#tRNAfragments) and racial disparities in triple-negative #breastcancer. In @aacr's Cancer Research: bit.ly/2FJvncF
@NIMHD @TNBCFoundation @PBCC @KomenPhilly @SusanGKomen @NCHD @jeffersonuniv
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