This is the official Twitter account for the Complex Interventions Division within @leedsCTRU, led by Prof @Amanda_Horler
Leeds, England
Joined June 2019
- Tweets709
- Following270
- Followers445
- Likes959
CTRU Complex Interventions retweeted
@AtlantisTrial results outlined in @NIHRevidence summary 👇
@alex_ford12399
@LeedsCTRU
@ComplexCTRU
@HazelEveritt
@Dr_SarahA
@riddmj
@Robbie_Foy
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CTRU Complex Interventions retweeted
We are so excited to be recruiting for Round 3 of our DTP. We have 38 amazing fully-funded projects at our 12 partner institutions listed here mrctmrpdtp.com/current-oppor… Please spread far and wide, closing date 15 Jan.
CTRU Complex Interventions retweeted
Interested in #LifeAfterStroke trials research #UKSF23
Please do get in contact with the LEAP team at @ComplexCTRU @LeedsCTRU
Email contact 👇
@amanda_horler is a marvellous machine of a human! What a gargantuan effort presenting so much about the exciting proposed LEAP #platform #trial at #uksf23. With co-lead @audreybowenprof (also a marvellous machine), I'm honored to be a co-app and hope it gets funded! 🤞 #rehab
CTRU Complex Interventions retweeted
We are counting down to #UKSF23. The @recreate_stroke team are looking forward to seeing everyone there and presenting their reflections on conducting a large, pragmatic multicentre stroke rehabilitation cluster RCT in NHS stroke services! @UKStrokeForum @ComplexCTRU
CTRU Complex Interventions retweeted
Great to hear Amanda Farrin sharing plans to boost research during clinical care - more speed, less waste at UK Stroke Forum today! @ComplexCTRU @LeedsCTRU @UKStrokeForum @amanda_horler
CTRU Complex Interventions retweeted
📢 Our @AtlantisTrial results demonstrating the benefits of amitriptyline for people with IBS are now published in the @TheLancet👇
@ComplexCTRU @LeedsCTRU
Delighted to see the @AtlantisTrial is published in this week’s issue of @TheLancet
thelancet.com/journals/lance…
In it, we report the effectiveness of amitriptyline as second-line treatment for #IBS in primary care
@amanda_horler @HazelEveritt @Dr_SarahA @riddmj @Robbie_Foy
CTRU Complex Interventions retweeted
Lovely to see @AtlantisTrial highlighted in the week's summary of important papers by @TheLancet 👇👇
@LeedsCTRU @ComplexCTRU
Good to see @AtlantisTrial published in @TheLancet last week in the roundup of this weeks important articles in @bmj_latest. Thanks to collaborators incl. @amanda_horler @HazelEveritt @riddmj @Dr_SarahA @Robbie_Foy
CTRU Complex Interventions retweeted
Its now only 2 weeks until #UKSF2023!
Looking forward to catching up with everyone and attending as many sessions as we can in what is a packed programme! 🤓
@UKStrokeForum @AUASResearch @ComplexCTRU
🚨 #UKSF23 Programme OFFICIAL!! 🚨
We are delighted to announce that the #UKSF23 programme is now available online. There are still one or two sessions that are currently TBC but we hope to finalise those shortly!
For a full breakdown, please visit
stroke.org.uk/professionals/…
CTRU Complex Interventions retweeted
Delighted to announce that the @AtlantisTrial of low-dose titrated amitriptyline as a second-line treatment for #IBS in primary care is now published online in @TheLancet
authors.elsevier.com/sd/arti…
I will be presenting the results today at 1430hrs at #UEGWeek2023
CTRU Complex Interventions retweeted
🚨Now published! 🚨The @AtlantisTrial showed benefits of amitriptyline in irritable bowel syndrome. Fantastic team work from all involved. Thank you to the participants and #teamGP for making it possible.
New online @TheLancet - Amitriptyline at Low-Dose and Titrated for #IBS as Second-Line Treatment in primary care (ATLANTIS): a randomised, double-blind, placebo-controlled, phase 3 trial
Catch the #UEGWeek presentation this pm by @alex_ford12399
thelancet.com/journals/lance…
CTRU Complex Interventions retweeted
New research led by Leeds, @unisouthampton, and @BristolUni has shown that amitriptyline, a cheap and widely available prescription drug, can improve symptoms of irritable bowel syndrome💊
IBS affects around 1 in 20 people worldwide🌍
ALT Person holding their lower stomach in pain.
CTRU Complex Interventions retweeted
📣 Read all about it
Our @AtlantisTrial results are published today demonstrating the benefits of amitriptyline in improving the symptoms of #IBS
Thank you to all who contributed to deliver this important trial
@ComplexCTRU
@alex_ford12399
@Dr_SarahA
@HazelEveritt
@riddmj
New online @TheLancet - Amitriptyline at Low-Dose and Titrated for #IBS as Second-Line Treatment in primary care (ATLANTIS): a randomised, double-blind, placebo-controlled, phase 3 trial
Catch the #UEGWeek presentation this pm by @alex_ford12399
thelancet.com/journals/lance…
CTRU Complex Interventions retweeted
Sheffield Hallam University has welcomed the 700th patient to its pioneering STAMINA study, which investigates the role of exercise in improving quality of life & combating the debilitating side effects of hormone treatment for prostate cancer
Read more: shu.ac.uk/news/all-articles/…
CTRU Complex Interventions retweeted
How to do a #ProcessEvaluation of an intervention optimisation study using a fractional factorial design within the #MOST framework 🤯
Check this out 👇 from the innovative @NIHRresearch #ROSETA program led by @SGSmith_87 with @ComplexCTRU
#MethodologyMatters
New preprint 📝❗️
See our new protocol of our process evaluation assessing:
1️⃣Acceptability
2️⃣Fidelity
3️⃣Trial experience
in a pilot fractional factorial trial with 4 intervention components supporting medication adherence in women with breast cancer
openresearch.nihr.ac.uk/arti…
CTRU Complex Interventions retweeted
📢 Finally the results are out from our @IBSTriton trial with @alex_ford12399 and Robin Spiller.
#COVID ended recruitment early, so these promising results need testing via a large pragmatic RCT in primary care
@LeedsCTRU @ComplexCTRU
@APandT
Ondansetron may be beneficial for #IBS with diarrhoea, but larger trials needed. @TRITON was a collaboration between @LeedsCTRU @amanda_horler and Robin Spiller.
Hopefully the trial and meta-analysis will pave the way for definitive trials of ondansetron in primary care.
CTRU Complex Interventions retweeted
Results are out!
"An intervention to support #stroke survivors and their carers in the longer term: results of a cluster randomised controlled feasibility trial (LoTS2Care)"
Thank you to everybody involved!
@CityOfResearch @ComplexCTRU @NIHRresearch
**HOT OFF THE PRESS**
Is a cRCT to assess the effectiveness of a longer-term self-management intervention for #stroke survivors and their carers feasible and acceptable??
Find out here! 👇👇👇
pilotfeasibilitystudies.biom…
@AUASResearch @LeedsCTRU @lots2care
CTRU Complex Interventions retweeted
The accelerometer repository is now on GitHub!
This allows anyone to add new methods, correct mistakes, or add more information (like further independent sample cross-validation, new R packages, etc.).
github.com/clevengerkimberly…
CTRU Complex Interventions retweeted
Research to develop trial methods are only useful when they are implemented in practise.
Sign up now to the @MRCNIHRTMRP webinar where @GilliesKatie will share findings on the challenges/opportunities of implementing research.
#Training #Webinar
eventbrite.co.uk/e/tmrp-webi…
CTRU Complex Interventions retweeted
❓want to do a #PhD with me, @SGSmith_87 & @GilliesKatie at @ComplexCTRU @LeedsCTRU to explore how we better deliver remote interventions in #RCTs
Supported via #PhD DTP @MRCNIHRTMRP
Find more on #FindAPhD 👇 findaphd.com/phds/project/re…
CTRU Complex Interventions retweeted
Thank you 🙏
Lovely to see you've selected the poster from our @ComplexCTRU @LeedsCTRU @MRCNIHRTMRP PhD student Sadia Ahmed, as one of the top 4 posters at #ICTMC2022
Paper writing in progress aiming to publish in 2023, so watch this space 👀
4. Measuring implementation of complex interventions - heterogeneity in approaches and lack of transparent reporting suggests guidance might be helpful #ICTMC2022
