@CoombsLab

The reading group twitter account for Coombs' lab

 Vancouver, British Columbia
math.ubc.ca/~coombs/
Joined November 2017
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Using Koopman mode decomposition (dynamic mode decomposition) with a mode overlap matrix to find functional communities in networks of coupled Kuramoto oscillators, which frequency/phase lock fastest: journals.aps.org/pre/abstrac…

Detection of functional communities in networks of randomly coupled oscillators using the dynamic...

Dynamic-mode decomposition (DMD) is a versatile framework for model-free analysis of time series that are generated by dynamical systems. We develop a DMD-based algorithm to investigate the formation...

journals.aps.org
"Neutral bots probe political bias on social media" rdcu.be/cy12P
How exactly does a fractional reaction-subdiffusion equation relate to its diffusion counterpart? See here in the case of having affine reaction terms: journals.aps.org/pre/abstrac…
"Beyond R0: heterogeneity in secondary infections and probabilistic epidemic forecasting" royalsocietypublishing.org/d…

Beyond R0: heterogeneity in secondary infections and probabilistic epidemic forecasting

Abstract. The basic reproductive number, R0, is one of the most common and most commonly misapplied numbers in public health. Often used to compare outbrea

royalsocietypublishing.org
Modelling the infectivity with time-dependent kernels taking containment measures into account, some of which are pushing the epidemic threshold up (a complexity science and asymptotic scaling perspective): journals.aps.org/pre/abstrac…

Epidemics with containment measures

We propose a tractable epidemic model that includes containment measures. In the absence of containment measures, the epidemics spread exponentially fast whenever the infectivity rate is positive...

journals.aps.org
"Models of SIV rebound after treatment interruption that involve multiple reactivation events" journals.plos.org/ploscompbi…

Models of SIV rebound after treatment interruption that involve multiple reactivation events

Author summary HIV-1 persists during suppressive antiretroviral therapy (ART) due to a reservoir of latently infected cells. When ART is stopped, HIV generally rebounds within a few weeks. However,...

journals.plos.org
Last week, the 2020 Ig Nobel Prize winners were announced. The Ig Nobel Prize goes to research that makes you laugh first and then think. improbable.com/ig-about/winn… @improbresearch
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Very cool paper on evolutionary loss of adaptive immunity in anglerfish: The immunogenetics of sexual parasitism science.sciencemag.org/conte…
Mathematical Model Shows How Sleep May Affect Amyloid-β Fibrillization sciencedirect.com/science/ar…
Noise amplification through nearly parallel eigenvectors of linearisation about resting state and strong separation of time scales: possible consequences for self-organization in noisy excitable systems? journals.aps.org/pre/abstrac…
Selection of spatiotemporal patterns in arrays of spatially distributed oscillators indirectly coupled via a diffusive environment doi.org/10.1063/1.5058741
Undulation enables gliding in flying snakes doi.org/10.1038/s41567-020-0…
SARS-CoV-2 T-cell epitopes define heterologous and COVID-19-induced T-cell recognition researchsquare.com/article/r…
medrxiv.org/content/10.1101/…
To mask or not to mask: Modeling the potential for face mask use by th... sciencedirect.com/science/ar…
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link.springer.com/article/10…
"A mathematical model describing the localization and spread of influenza A virus infection within the human respiratory tract" journals.plos.org/ploscompbi…

A mathematical model describing the localization and spread of influenza A virus infection within...

Author summary This work proposes a new way to think about and model the dissemination of an influenza A virus (IAV) infection within the human respiratory tract (HRT). The computational model takes...

journals.plos.org
If containment is not possible, how do we minimize mortality for COVID-19 and other emerging infectious disease outbreaks? medrxiv.org/content/10.1101/…

If containment is not possible, how do we minimize mortality for COVID-19 and other emerging...

If COVID-19 containment policies fail and social distancing measures cannot be sustained until vaccines becomes available, the next best approach is to use interventions that reduce mortality and...

medrxiv.org
imperial.ac.uk/media/imperia…
Accelerated viral dynamics in bat cell lines, with implications for zoonotic emergence doi.org/10.7554/eLife.48401

Accelerated viral dynamics in bat cell lines, with implications for zoonotic emergence

Bats' uniquely robust innate antiviral immune defenses select for faster transmitting viruses likely to generate extreme virulence upon spillover to secondary hosts with immune systems divergent from...

elifesciences.org
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