We demonstrate that the autoimmune phenotype is associated with a populations of effector CD8 T cells with a phenotype similar to short lived effector cells (SLEC) in viral infection. Read on to find out more: journals.aai.org/jimmunol/ar… @BetterKidneys
Just published! Prolidase deficient mice have increased incidence of anti-nuclear antibodies, immune complex deposition and altered T cell population composition.
journals.aai.org/jimmunol/ar…
Delighted to share our paper on autoimmunity due to prolidase deficiency. We confirm loss of PEPD results in ANAs and renal immune complex deposition, assoc with T cell activation. journals.aai.org/jimmunol/ar…
A refreshingly off-corona Cornall & Bull journal club today from Cell & Singh et al, understanding the somatic mutations that drive production of pathogenic autoantibodies - what an extensive body of multi-omic work!! cell.com/cell/fulltext/S0092…
Just published! Have a read of our new paper describing the Lin28b/Let-7 switch that drives positive and negative selection in B cells during ontogeny. @PNASNews #Bcells #ontogeneticswitch #selection
pnas.org/content/early/2020/…
Welcome to Oxford life newly matriculated PhD students, Jian-wei and Aneesha! #penguinlife @BetterKidneys
Congratulations Sir Peter Ratcliffe for @NobelPrize
Huge congratulations to Sir Peter Ratcliffe @NDMOxford
@magdalenoxford @TheCrick - winner of the 2019 #NobelPrize in Physiology or Medicine! #Nobel2019
Fantastic journal club learning about the newly discovered subset of IL-13 producing T follicular helper cells that drive high affinity IgE production #Science #TFH13 #fridayjournalclub #CornallLab #BullLab
science.sciencemag.org/conte…
Lovely to catch up with old RA, Eleanor for a spot of hummus with the Cornall lab and @BetterKidneys 🥙🌯
How many foreign invaders will your immune system battle today? 👾👾👾 #TheBattleWithin
youtube.com/watch?v=1TVJJ0HG…
What does #immunology and space invaders have in common👾🦠?? Check it out in our new animation! Well done to @CornallLab and Davis lab for the great video!
