Group leader, Norwich Medical School (UEA)... membrane proteins, mitochondria in health and disease, bioenergetics

Norwich, England
Joined March 2013
Paul Crichton retweeted
This year the Xmas Bioenergetics meeting is in York! It's a friendly one-day meeting around anything to do with bioenergetics. Please retweet and share
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Excited to share our work on how ECF #transporters use ATP binding to charge a molecular spring and tune the #membrane shape to expel membrane-embedded substrate-binding proteins from the docking site into the membrane. #cryoEM #Biochemistry #MDsimulation rdcu.be/dhJvy
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Delighted with our latest work published @JAMAInternalMed led by @justvick #WIC @uniofeastanglia @NNUH on Risk Factors for Long Covid. Reduce the risk by getting vaccinated & HEALTHY LIFESTYLE #vaccines #work Full article: jamanetwork.com/journals/jam… VACCINES WORK @medtwitter #epeeps
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A huge thank you to our scientists from UEA who taught the year 5s about growth, reproduction and energy🔬They especially enjoyed the explosion… more photos to follow …
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Amazing work by Vasso & colleagues @Mitocarriers mapping the substrate binding site of the mitochondrial ADP/ATP #carrier by exploiting elegantly substrate-induced shifts in thermostability assays doi.org/10.1038/s41467-022-3… @STavoulari @thecarrierking @MRC_MBU
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Our paper is in press! The human mitochondrial pyruvate carrier (MPC) was a hard nut to crack. We provide critical insights on the protein composition and inhibitor binding to facilitate drug discovery efforts. sciencedirect.com/science/ar…
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Paul Crichton retweeted
If you're an undergraduate medical student thinking of intercalating, come along to our Intercalation Evening on 25 November on West Campus to find out more. bit.ly/3bT0xiy
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Dr Justin O'Grady (@Justin_OGrady) will be on @BBCLookEast this evening with @BBCwestcott to discuss the new variants of #coronavirus and how scientists at the Quadram are mapping the spread of the virus in #EastAnglia through genome sequencing. 📺 Tune in from 6.30pm!
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Meet my neighbor Noreen. Proudly announced she got a XMAS 🎁 from 🎅 in the form of a @pfizer #VACCINE from @anasCUH_NHS. Posted with permission. BE LIKE NOREEN 😊 Please RT #covid #getavaccine @NHSMillion @exerciseworks @mmamas1973 @purviparwani @DrMarthaGulati @hvanspall @Hragy – at Cambridge, England
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Paul Crichton retweeted
Congratulations to four pioneering female members of our UEA community for awards in the Queen's Birthday Honours! 👏 Laura McGillivray, Prof Laura Bowater, Prof Gillian Schofield & Prof Amelia Fletcher; we're proud of all four of them. Read more here: uea.ac.uk/news/-/article/uea…
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Paul Crichton retweeted
"He demonstrates all that can be achieved in a scientific career and serves as a great example for all students at UEA today." Read about UEA grad Dr Michael Houghton, jointly awarded the Nobel Prize for Medicine yesterday for his life-saving work 🔬 bddy.me/36z1yep
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Paul Crichton retweeted
Say hello to 'Home' The weather might be turning, but you can still get outside & enjoy our campus during the day in this new social space. Find Home on the grassy area beyond the SU shop 🏠🍃 Remember, social distancing rules apply, & you must attend in groups of 6 or less.
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Paul Crichton retweeted
The Tate group @MRC_LMB is happy to contribute to our collective understanding of arrestin-coupling to #GPCRs. We present a #cryoEM model of the β1AR-βarr1 complex bound to formoterol, an arrestin-biased agonist, in nanodisc. @JGarciaNafria @arshukla nature.com/articles/s41586-0…
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Paul Crichton retweeted
Publicly accessible via SharedIt. rdcu.be/b40Ze
The Tate group @MRC_LMB is happy to contribute to our collective understanding of arrestin-coupling to #GPCRs. We present a #cryoEM model of the β1AR-βarr1 complex bound to formoterol, an arrestin-biased agonist, in nanodisc. @JGarciaNafria @arshukla nature.com/articles/s41586-0…
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Paul Crichton retweeted
Hundreds more people can be tested for #coronavirus every day in #Norfolk thanks to new kit from UEA's Medical School (@UeaMed) A huge thank you to @NNUH @EarlhamInst and @TheQuadram for their support 🙏 #ThinkingWithoutBorders #WeAreTogether ow.ly/aH3I50zmbZY
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Paul Crichton retweeted
Researchers at UEA have launched a project to 3D print ventilator parts, masks and other critical equipment to battle the #Covid19 virus. The project is being led @dr_aramsaeed and supported by @Ben_garrod: ow.ly/cBXA50yTgBj #ThinkingWithoutBorders #Coronavirus
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This is amazing - thank you! 💙
Technicians in our New Science Building are hard at work creating hand sanitiser gel for #NHS partners and we’re still keen to hear from any organisations who can share ethanol or bottling containers: ow.ly/BNzb50ySOm4 #ThinkingWithoutBorders #COVID19
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