Redefining digestive health by pioneering non-endoscopic diagnostics, enabling early detection of diseases and access to care for everyone, everywhere.

Cambridge, England
Joined June 2020
Replying to @CytedHealth
@CytedHealth’s EndoSign detects Barrett’s esophagus with 90% sensitivity in US study pharmadevicenews.com/cyted-h… EndoSign achieved 90% sensitivity and 86% specificity for Barrett's esophagus in a prospective 324-participant US study, with successful cell collection in 95% of patients. Cyted Health also reported 100% sensitivity for dysplasia and esophageal cancer, but positive results still require endoscopy and the molecular test itself is not FDA-cleared. #CytedHealth #EndoSign #DETECTME #BarrettsEsophagus #EsophagealCancer #MolecularDiagnostics #EarlyDetection #MedicalDevices #Gastroenterology #ACG2026
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💭 What does long-term follow-up 📊 on low-risk patients w/ Barrett's esophagus triaged with 🧽 capsule sponge look like❓ ✅ Check out these interesting and reassuring results from a study (relatively small sample size) @FrontGastro_BMJ 🖇️ bit.ly/4moRYQ1 that showed ↪️ No significant differences in the detection of dysplasia or cancer in patients with follow-up endoscopy vs repeat capsule sponge testing and endoscopy ↪️ All cases w/ HGD and cancer were detected by repeat capsule sponge testing w/ positive biomarkers (atypia and p53) 👏 Thank you to authors @siobhan_chien @GastronautIan Paul Glen Gavin Bryce Michael Miller Neil Cruickshank Andrew Crumley Jonathan Fletcher Ivan Gunjaca Perminder Phull @JKApollos Kevin Robertson Grant M Fullarton @PhilSmithIsBack @OTavabie @dr_aditi_kumar @TrevorTabone @eathar_s @IrenePerezMD @KGananandan @zare_benjamin @medicalreg @dtleiberman @BASLedu @BSGtrainees @ulstergastro #GITwitter
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🧪 Capsule Sponge Triage in Reflux — Can We Reduce Unnecessary Endoscopy? 4-year prospective cohort, 871 patients. Key findings: • 88% adequate samples • 62% avoided endoscopy • Abnormal CS (~10%) strongly predicted significant pathology • PPV for Barrett’s: 43.5% • NPV: 98.2% • >97% patient acceptability Detected: 1 cancer, 2 dysplasia, 34 Barrett’s cases. Long-term follow-up confirmed safety. Takeaway: Capsule sponge safely stratifies reflux patients, increases diagnostic yield, and optimizes endoscopy resources. #GERD #BarrettsEsophagus #Endoscopy #GIInnovation #GastroAGI
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🚨 🗣️ Fantastic new original research from the CYTOPRIME 2 study 💥. Thanks to @DrDanielleMorr1 @CytedHealth and team for demonstrating that capsule sponge testing 🧽 is a practical and scalable approach to earlier detection of Barrett's oesophagus and oesophageal cancer 👏 . Should we be implementing this in the community as a screening test for patients with GORD 🤔 💭 ?! fg.bmj.com/content/early/202… @PhilSmithIsBack @OTavabie @dr_aditi_kumar @TrevorTabone @eathar_s @IrenePerezMD @KGananandan @zare_benjamin @medicalreg @dtleiberman @BASLedu @BSGtrainees @WorldGastroOrg @ulstergastro @pancreatitis_nl @SEEDendoscopia @EASLedu @AmCollegeGastro @Aegastro @SAGES_updates @UHSEndoscopy @WAGE_media #GITwitter #gastroenterology #Endoscopy #MedEd
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Delighted to be featured on @TheLancet podcast sharing our findings from our recent BE surveillance paper published in the Lancet! Tune in wherever you get your podcasts: thelancet.com/multimedia/pod… #podcast #surveillance #barretts
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📅 Today is World Barrett's Oesophagus Day Persistent heartburn 🔥 for over 3 weeks could be #MoreThanJustHeartburn. Don’t ignore it — speak to your GP. 🩺 More info 👉 heartburncanceruk.org/barret…
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Congratulations @LSCICB cancer alliance @cytedhealth and @innovationnwc on winning the Industry Collaboration Primary Care award for the CYPTOPRIME2 collaboration, delivering early diagnosis. @arc_nwc #nwcawards
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Exciting news! Our Capsule sponge testing team is a finalist for the #NIHRImpactPrizes! Honoured to see our research celebrated for its impact. Winners will be announced on 20 March —stay tuned! Learn more about NIHR Impact Prizes: nihr.ac.uk/about-us/our-impa…
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Only 25% of oesophageal cancer cases are caught before the cancer spreads 🩺.1 Early diagnosis saves lives.2 Find out how persistent heartburn could be #MoreThanJustHeartburn here 👉 heartburncanceruk.org/?utm_s…
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Great news for @LessSurvivable cancers awareness week! Enormous potential for #cytosponge to make an impact on #earlydiagnosis for #oesophageal cancer.
The national pilot of capsule sponge testing in Scotland is now a finalist in the @HSJnews awards! We’re incredibly proud to have played our part in helping Scottish patients experience the benefits of capsule sponge, and it has been great to see uptake continuing. #CytoScot
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doi.org/10.1111/apt.18472 @NHSEngland realworld study of non-endoscopic #capsulesponge triage in patients with reflux: Safe,cost effective acceptable, identifies #BarrettsOesophagus avoids unnecessary gastroscopy,reduces #waitinglists time for new guidance in reflux?
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A huge milestone for cancer research in Cambridge, and beyond. Well done to Prof Rebecca Fitzgerald and team at @EarlyCancerCam, who've led this project! Our @markowetzlab is looking at how we can use AI to accelerate analysis of the data borne from the trial. @CRUKCamCentre
A new trial we’re funding uses an innovative ‘pill-on-a-thread’ test to screen people with heartburn for Barrett’s oesophagus, a condition that can lead to oesophageal cancer – and it's easier and cheaper than endoscopies. Read more below 👇

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The BEST4 Screening trial has welcomed its first participants. The trial, funded by @CR_UK and @NIHRresearch, will find out if a capsule sponge test can screen for oesophageal cancer. The trial will be led from @CUH_NHS and @Cambridge_Uni. Read more ➡️crukcambridgecentre.org.uk/n…
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💊 New clinical milestone! 💊 The first participant has joined @Cyted’s oesophageal cancer screening trial! The trial will screen 120,000 participants using @Cyted’s 10-minute “pill-on-a-thread" capsule sponge test, potentially slashing diagnostic wait times. Many congratulations to Professor Rebecca Fitzgerald, and everyone at @Cyted, @QMUL, @CRUK_CI and @EarlyCancerCam! Find out more here: 👉 bit.ly/3ZrQ47q #OnMyHorizon @NHSEngland, @NHSScotland, @gatesfoundation, @MarcelGehrung
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This International Men's Day, let's talk oesophageal cancer - the 4th biggest cancer killer of UK men. Know the signs: persistent heartburn, difficulty swallowing, coughing & weight loss. Early diagnosis saves lives. 🧡 #InternationalMensDay #MensHealth
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The Cambridge Symposium on Oesophageal Cancer #camsoc2024 has kicked off! Thanks to Rob O’Neill for the welcome, we start with a talk from @RC_Fitzgerald ‘The past, present and future of early detection for oesophageal cancer’
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