Daniel retweeted
Lets promote and advance the field of pre-COPD. Recognising and tackling the pre-disease and early disease states have helped reducing the burden of many chronic diseases, so why not in COPD? thelancet.com/journals/lanre…
Daniel retweeted
Grateful to @LancetRespirMed for the kind profile. Honoured and humbled to be featured. Thank you.
Shyamali Dharmage: mapping lung health trajectories across the life course - The Lancet Respiratory Medicine thelancet.com/journals/lanre…
Daniel retweeted
1/2 New pub in @JAMA_current from #CLAIR! New Diagnostic Schema for #COPD 15.4%⬆️COPD among smokers; 6.4%⬇️ diagnosis among airflow obstruction but no symptoms/imaging findings. Newly detected have high risk of mortality, exacerbations and FEV1 decline jamanetwork.com/journals/jam…
Daniel retweeted
Temporal Exploration of COPD Phenotypes: Insights from the COPDGene and SPIROMICS Cohorts
The authors present a method that phenotypes and models disease trajectories in a large population of COPD patients
@meilan_han
@umichmedicine
@andrei_zinovyev
tinyurl.com/yvru6rp2
Daniel retweeted
A new review discusses challenges and pitfalls in the diagnosis and management of chronic cough that is unexplained after a complete evaluation or that is refractory to treatment for identified causes.
Read the Review Article “Unexplained or Refractory Chronic Cough in Adults” by Richard S. Irwin, MD, and J. Mark Madison, MD, from @umasschan: nej.md/4hGwQRl
ALT An illustration showing the model of the cough reflex.
Daniel retweeted
🌏Respirology
"Building Respirology" - a 'looking back' Editorial by outgoing Co-Editor in Chief Prof Philip Bardin in #Respirology
#FreeAccess
onlinelibrary.wiley.com/doi/…
@PhilBardin @APSRapsr
Daniel retweeted
Original Article: Long-Term Oxygen Therapy for 24 or 15 Hours per Day in Severe Hypoxemia (REDOX) nej.md/4cR3pK4
Editorial: Making Long-Term Oxygen Therapy Less Burdensome nej.md/4ejhYqX
#ERSCongress | @EuroRespSoc
ALT Bar charts showing the patient-reported daily duration of long-term oxygen therapy (LTOT) at 3 and 12 months.
ALT The cumulative incidence of hospitalization or death from any cause (primary outcome) (Panel A), hospitalization for any cause (Panel B), and death from any cause (Panel C) within 12 months after randomization.
Daniel retweeted
👇👇
Grateful for this @EuroRespSoc CADSET collaboration paper - such a wonderful teamwork! 🙏 First author Dr Hernandez-Pacheco - big congrats!
Certain genetic variants that have previously been linked to the lung disease COPD can explain reduced lung function already in children and adolescents, according to a study in @eClinicalMed.
Research by @ErikMelen et al.
news.ki.se/genetics-of-copd-…
Daniel retweeted
Pre-COPD is here to stay until we find solutions-let’s work together to solve this novel paradigm
Article Alert: Treatable traits in pre‐COPD: Time to extend the treatable traits paradigm beyond established disease - Dharmage - 2024 - Respirology - Wiley Online Library
onlinelibrary.wiley.com/doi/…
Daniel retweeted
Original Article: Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity (SURMOUNT-OSA) nej.md/4coe9zv
Editorial: Entering a New Era in Sleep-Apnea Treatment nej.md/3RBd13I
#ADASciSessions
Daniel retweeted
Can We Use Lung Function Thresholds and Respiratory Symptoms to Identify Pre-Chronic Obstructive Pulmonary Disease?
Pre-bronchodilator FEV1/FVC at the 10th percentile identifies those at risk of developing COPD in community settings
🔗 tinyurl.com/57ppr8be
Excited to see our work published in the Blue Journal - many thanks to my supervisors @CDharmage, @Perret777 and Caroline Lodge
The Blue Journal thanks Daniel Tan for his contribution to the June 15 issue
Can We Use Lung Function Thresholds and Respiratory Symptoms to Identify Pre-Chronic Obstructive Pulmonary Disease?
@DanielJ_Tan
tinyurl.com/mpadwzct
UCAP demonstrates clinical benefit of screening and early treatment of obstructive airways diseases.
Presented at #ATS2024:
UCAP trial: Case finding for symptomatic adults with undiagnosed asthma or COPD was coupled with a randomized trial to compare pulmonologist-directed and usual care. Pulmonologist-directed care led to less health care utilization. nej.md/4bEPnuC
ALT Page 1 of the Original Article "Early Diagnosis and Treatment of COPD and Asthma — A Randomized, Controlled Trial"
Daniel retweeted
Presented at #ATS2024:
A study assessed the clinical, occupational, and financial effects associated with changing from race-based to race-neutral equations for the interpretation of lung function on millions of patients. Full study results: nej.md/44K5TaC
ALT Graph showing outcomes for study participants with regard to nonobstructive ventilatory impairment when lung function was interpreted with the use of race-based Global Lung Function Initiative 2012 (GLI-2012) equations and with race-neutral GLI-Global equations.
Daniel retweeted
This is such an exciting project. Hope we can find ways to arrest or slow the progression pre-COPD to #COPD @meilan_han
🥳@nhmrc has awarded $3 million Clinical Trial & Cohorts Studies grant to @unimelbMSPGH 's Prof @CDharmage and her team. It will fund the worlds' 1st trial of triple therapy for #pre-COPD within the #TAHS cohort. A major step towards advancing the novel paradigm of pre-COPD!
Daniel retweeted
A pleasure to join JAMA Statistical Editor Issa Dahabreh @CAUSALab @HarvardChanSPH in writing on a framework medical journals might use to approach causal inference from observational studies
Read the Special Communications below & accompanying editorial jamanetwork.com/journals/jam…
🧵 New Special Communication examines drawing causal inferences about the effects of interventions from observational studies in medical journals and suggests a framework that might be used.
ja.ma/3UxeAjL
Daniel retweeted
Interstitial lung disease.
Rheumatoid arthritis and idiopathic pulmonary fibrosis: a bidirectional Mendelian randomisation study thorax.bmj.com/content/early… @Liv_leavy @leticiakawano
Daniel retweeted
A tribute to the 6th anniversary of the extraordinary #TAHS study by Dr Dinh Bui at #TSANZSRS2024
Daniel retweeted
For most people, lung function trajectories are established early in childhood. Asthma and airways hyper-responsiveness are associated with life course-persistent adverse trajectories. thorax.bmj.com/content/early…
Daniel retweeted
Lung-function development can be altered by several host & environmental factors during the life course, resulting in a range of lung-function trajectories existing in the population.
A Review presents progressive research into lung-function trajectories: hubs.li/Q02psGjw0
ALT Figure showing lung-function trajectories from childhood to adulthood. Copyright: 2024 Elsevier Ltd. All rights reserved.