Super excited that the first preprint from the lab is out! Led by an amazing student, Gaurav
@gauravkvaidya, jointly supervised with Mike @mwdorr.
The first preprint from my PhD is out!
How does an animal choose between two completely different reproductive fates?
Here’s how one planarian does it 👇
biorxiv.org/content/10.64898…
Jun-Ru Lee 李俊儒 retweeted
⚡ Our paper is now out in @NaturePhysics !
nature.com/articles/s41567-0…
🎉 Excited to share our new work: “Adhesion-driven tissue rigidification triggers epithelial cell polarity”, now on @biorxivpreprint !
A huge thank you to @petridou_ni , Bernat, @CristinaPallCar , Adrián, and everyone involved! 🙌
🧵⤵️
Jun-Ru Lee 李俊儒 retweeted
Now published. Congrats to Soham and all co-authors! science.org/doi/10.1126/scia….
@embl
We thought we were just studying mesoglea biogenesis…Turns out Nematostella has been hiding a sophisticated backup pressure valve! Work driven by the talented PhD student @SohamBasu13! @EMBL #nematostella #morphogenesis biorxiv.org/content/10.1101/…
Jun-Ru Lee 李俊儒 retweeted
🏅 Fifth Place – DevBio Art Contest 🎨 “The Leech Family” 🪱 Helobdella austinensis, a quirky segmented worm that’s taught us decades of developmental biology! 🧬 This clay piece by @biyolokum captures their quirky life as hermaphroditic parents carrying babies on their belly
Jun-Ru Lee 李俊儒 retweeted
New preprint from the lab!
How do tissue shapes influence cell fate decisions?
By manipulating brain organoid geometry, we show that lumen rounding directs apical progenitor division mode and promotes the emergence of basal progenitors.
biorxiv.org/content/10.64898…
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Jun-Ru Lee 李俊儒 retweeted
Now online! Deciphering mechanical determinants of morphological evolution dlvr.it/TRfhcK
Jun-Ru Lee 李俊儒 retweeted
Tissue phase transitions in development: more than just mechanics
In this Review, Laura Rustarazo-Calvo, Karen Grace Soans and Nicoletta I. Petridou discuss tissue phase transitions in development: doi.org/10.1242/dev.205219

ALT Figure 1 of the article: Fig. 1. Phase diagram of tissue material phase transitions and examples. (A) Schematic diagram showing how continuous changes in microscopic dynamics (control parameter) lead to abrupt, drastic, and non-linear shifts in macroscopic properties that define the material response (order parameter). (Aa-Ab) Exemplary phase transitions as traditionally described in non-living matter, e.g. for water (Aa), as well as in living matter, e.g. for embryonic tissues (Ab). Yellow areas indicate fluid-like tissues and regimes. Blue areas indicate solid-like tissues and regimes. Magenta dashed line depicts the critical point. Orange line marks particle and cell trajectories.
Jun-Ru Lee 李俊儒 retweeted
New publication from the Adler Lab!
We discover new regulators of stem cell differentiation, Robo and Anosmin!
nature.com/articles/s41467-0…
@Cornell @SocDevBio #basicresearch
Jun-Ru Lee 李俊儒 retweeted
🎄 Day 4 of the 24 Days of Development ✨🧬
In 1984, Drosophila homeotic genes were found to be conserved across animals, including humans 🧬🐸. This article highlights a shared genetic toolkit for embryonic development 🔬🌟🎁 doi.org/10.1016/j.ydbio.2024…
Jun-Ru Lee 李俊儒 retweeted
🐠 Medaka (Oryzias latipes) ✨ A tiny fish with big developmental insights! 🧬 Medaka is perfect for studying sex determination, germ cell development, pigmentation, and environmental effects on embryos 📸 Image by Philipp Keller #ModelMonday #DevBio #EvoDevo
Jun-Ru Lee 李俊儒 retweeted
Crosstalk between tissue mechanics and BMP4 signaling regulates symmetry breaking in human gastrula models dlvr.it/TP6kS6
Jun-Ru Lee 李俊儒 retweeted
Ever wondered how metabolism regulates embryonic development? Our recent work demonstrates that metabolism has a signaling module controlling the tempo of embryonic axis segmentation.
science.org/doi/10.1126/scia…
Jun-Ru Lee 李俊儒 retweeted
Online now: Proteomics-based multi-omics identifies the roadmap of transcription-translation-protein dynamics in planarian regeneration dlvr.it/TN6HnP
Jun-Ru Lee 李俊儒 retweeted
Nature research paper: The genomic origin of the unique chaetognath body plan
go.nature.com/41xxhYY
Jun-Ru Lee 李俊儒 retweeted
We are searching for an enthusiastic scientist to join our team and establish annual killifish as a model system for early developmental biology and biophysics! @embl
Apply here: embl.wd103.myworkdayjobs.com…...
Please re-post 🙏
The Petridou group at EMBL-Heidelberg is hiring🥳🥳
embl.wd103.myworkdayjobs.com…
Jun-Ru Lee 李俊儒 retweeted
Ghosh, Prasad et al. @iiserkol elucidate the role of ecdysone signaling in orchestrating the removal of nurse cells by transforming the epithelial follicle cells to a phagocytic fate during late #Drosophila #oogenesis. hubs.la/Q03pvtf90
#Development #CellDeath
Jun-Ru Lee 李俊儒 retweeted
Open call! The EMBO Global Investigator Network supports group young leaders who are setting up their laboratories in Chile, India, Singapore or Taiwan. Apply by 1 May: embo.org/funding/fellowships…
#ResearchFunding #LifeSciences
Jun-Ru Lee 李俊儒 retweeted
With @rinklab we looked into details of the stem cell system of catenulids. Surprisingly, it was very different from the canonical neoblast-based systems of other flatworms. What does it tell about the evolution of stem cells and regeneration? Check here:
bit.ly/3WK2ZzR
Jun-Ru Lee 李俊儒 retweeted
A comparative analysis of planarian regeneration specificity reveals tissue polarity contributions of the axial cWnt signalling gradient. | bioRxiv biorxiv.org/content/10.1101/…

























