Neuroscientist at Columbia University; Studying neurobiological mechanisms underlying stress vulnerability and resilience. Looking for postdocs!

Columbia University
Joined December 2015
ventral CA1 (vCA1) responds to perseverative errors and is functionally required for adapting to a rule change, whereas dorsal CA1 (dCA1) stabilizes newly learned information after an initial, vCA1-dependent adaptation phase. (2/2)
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The discovery paves the way for a new type of antidepressant that inhibits the chemical (SGK1). “Current antidepressants are often less effective for people with a history of childhood adversity," says the study's leader @Der_Scientist. Read more: cuimc.columbia.edu/news/brai…
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New paper from our lab out this week! We show that hippocampal SGK1 links early life adversity, stress, and genetic risk to depression, and that inhibiting SGK1 promotes resilience, boosts neurogenesis, and rescues dentate gyrus function. Link ⬇️ nature.com/articles/s41380-0…
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Very grateful especially to the fantastic collaboration with @SilveiraPP , @JPablo_Neuro, @LudmerCentre, and Milenna van Dijk!
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Our new paper is out in ⁦@npp_journal⁩ showing female-specific effects of early adversity on stress reactivity, adult neurogenesis, and neuroinflammtion across development, and how they can be rescued by raphe 5HT1A knockdown and increased serotonin! nature.com/articles/s41386-0…
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Christoph Anacker retweeted
Had such nice time in Mainz @ #RESILIENCE2024 - great, interdisciplinary science, top-notch entertainment. Europe really knows how to do it! Great hanging out w/ @Der_Scientist @clbockting . What an amazing night w/ fantastic band, food adventure, everyone dancing! @joeribordes
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Christoph Anacker retweeted
Huge congratulations to our fantastic postdoc Maryam Hasantash for receiving a 2024 NARSAD Young Investigator Award to study neural circuits of stress susceptibility and resilience! #BBRFoundation
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Ok so we didn’t take an official panel photo but we did manage a Texas BBQ one thanks @Der_Scientist. So honored to be a part of this #SOBP2024 crew: hearing amazing science, making new friends, & eating like it’s a Philly meat trough. Thanks Victor & Nesha for the invite!
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Such a great experience being part of this fantastic panel on Teen Mental Health and the role of social media last week! Great initiative by @_HDRF and @BoysClubNY
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Christoph Anacker retweeted
Check out our new paper by Twitter-less John Bickle showing that activating 5-HT1A (hetero-) receptors in the dentate gyrus inhibits neuronal activity and confers resilience to social defeat stress in mice! ⁦⁦@anacker_lab⁩ ⁦@Der_Scientist⁩ biologicalpsychiatryjournal.…
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Christoph Anacker retweeted
Come chat with Travel Awardee @lauren_malave about her fascinating Postdoc work tonight at 5pm during the poster session at T35! #ACNP2023
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Christoph Anacker retweeted
Check out this new paper by @MilennavanDijk in collaboration with @Der_Scientist showing that Dentate Gyrus microstructure in humans is associated with vulnerability and resilience to maternal stress exposure! Great translation of our rodent findings into human populations.
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Such a stimulating meeting discussing science and project ideas with the team of @UnivParisSaclay and @MOODS_Inserm at @ColumbiaPsych . Thanks @DrChristineAnnD and @DenisJDavid for organizing such a great day!
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Such a fantastic comprehensive paper from @MitoPsychoBio lab characterizing stress effects on mitochondria across the brain. So happy to have been part of this great collaboration!
How we interact with the world – our perceptions, reactions, behaviors – are driven by brain biology. But what part? We find that mitochondrial energy production capacity in specific brain areas explains a large fraction of mouse behavioral differences nature.com/articles/s41467-0…
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Christoph Anacker retweeted
How we interact with the world – our perceptions, reactions, behaviors – are driven by brain biology. But what part? We find that mitochondrial energy production capacity in specific brain areas explains a large fraction of mouse behavioral differences nature.com/articles/s41467-0…
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Christoph Anacker retweeted
So incredibly happy to receive the ACNP travel award this year! I’m looking forward to engaging with this amazing group again. Thank you @ACNPorg @Der_Scientist @anacker_lab ! 😄
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Massive congratulations to DR. @dixon_ronie - the 1st grad student of the Anacker lab!🥳 👏👏 So incredibly proud of your accomplishment! And thanks to @DrZoePhD for coming all the way to NYC for the defense! @DrChristineAnnD @mark_ansorge @DANLAB_Columbia
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Christoph Anacker retweeted
⁦@LEARNMEM⁩ ⁦@DrSebnemT⁩ ⁦@Der_Scientist⁩ @jsnsndr2 & Victor Luna & Nesha Burghardt ⁦@Rene_Hen⁩
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Such an honor to be part of this group and to write this important article together on better inclusion of the LGBTQIA2S+ community!
We’re out! This is what happens when we put together a study group where beautiful minds speak out @ACNPorg Congrats!Teddy Goetz @DrGlitterbear @JaredWYoung @NeirEshel @Der_Scientist @krishuponastar @dianeehrensaft1 @earthagae @EKaleEdmiston @npp_journal nature.com/articles/s4138
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