PhD student at the Fischer-Friedrich Lab, @FischerFriedLab, PoL, TU Dresden. Looking at cellular proliferation and epithelial-mesenchymal transition in cancer.

Joined March 2022
My PhD work is now available in bioRxiv! biorxiv.org/cgi/content/shor… We investigated how mesenchymal-epithelial transition affects tumor growth, focusing on cell adhesion signaling pathways and morphology-driven changes in the interactions with immune cells ⬇️🧵@FischerFriedLab
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A new CRISPR approach developed by a team led by Jennifer Doudna can selectively destroy cancer cells carrying p53 mutations—one of the most common drivers of cancer—while sparing healthy cells. A promising step toward tackling “undruggable” cancers. bit.ly/4er5bEl
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Gina Dimari retweeted
Organoids for drug “secretion” nature.com/articles/s41551-0…
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Last week I defended my PhD thesis 🥳 Can't be any more grateful for all the support I had throughout this journey 🥰
Congrats to our latest graduate Gina Dimari 🤩🥳💐@FischerFriedLab @PoLDresden freshly defended @tudresden_de Faculty of Biology. Thanks to collaborators of the project Alexander Wurm and Anke Fuchs recently published @iscience
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Why do secondary #tumors go for #MET during the metastatic cascade? Our new study suggests that immune evasion—rather than faster proliferation—might give them the edge. 👉 cell.com/iscience/fulltext/S… #CancerResearch #TumorBiology #Immunology #Metastasis
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Exciting news for new #students! This year our #international 'Physics of Life' MSc program will offer 3 #scholarships - share and spread the word! 🤓 Learn more: tud.link/ayajef Students receive €300/month for 1 year, funded by Friends & Supporters of TU Dresden
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The biotech company Colossal Biosciences declared on Monday it had “resurrected” the dire wolf. The bold claim was immediately met with skepticism and outrage from scientists on social media. scim.ag/3G2zBzi
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Gina Dimari retweeted
Taking phones off the internet boosts mental health. People were randomly assigned to block mobile internet for 2 weeks. They socialized, exercised, and read more—and became happier, less depressed & anxious, and more focused. Being unglued from devices is good for well-being.
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☕️Afonso et al. show that, during #anaphase, chromosome movement can be driven by large cytoplasmic flows. These dynein-dependent cytoplasmic flows scale with cell size, slowing in smaller cells, thereby scaling anaphase. bit.ly/4bpoMCU
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#YerbaMate makes the third most popular caffeinated drink in the world, but it’s unrelated to tea and coffee. The first reconstruction of its genome is helping us understand how multiple species have evolved to synthesise caffeine. elifesciences.org/articles/1…
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I’m extremely excited to be in sunny San Diego ☀️ attending #CellBio2024 🤩 if you are here too and interested in #EMT, #CancerMetastasis and #CellAdhesion signaling come check my poster P2871 on Tuesday at 1:30 pm at board 492 🙌🏻
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This year’s #NobelPrize in Physiology or Medicine honours two scientists for their discovery of a fundamental principle governing how gene activity is regulated. They discovered microRNA, a new class of tiny RNA molecules that play a crucial role in gene regulation.
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A @sigtrans_sttt review to get you talking! 💬 A team from Zhengzhou University sheds light into the temporal mechanisms of pre-metastatic niche formation such as #EMT, immunosuppression, #ECM remodeling, and metabolic reprogramming. 📍 go.nature.com/3XMA5yW
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And finally, in co-culture with PBMCs, MET-induced tumor spheroids showed reduced PBMC-induced apoptosis and PMBC-infiltration. Most likely due to confined morphology and changes in immunomodulatory molecules. Want to know more? 😁🧐Read our preprint on biorxiv.org/content/10.1101/…
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Thanks to @FischerFriedLab and all the co-authors 😁🤗
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Throw back to our last’s week PhD retreat! Had a lot of fun in this amazing setting and got to share a bit of my work in a contributed talk as well 😄 We are so lucky to get to do our PhD in DD with such a great and supportive community of predocs! @digsbb @imprs_mpicbg
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Last Friday we had some fun while showing biological processes that involve changes in cell mechanics! (Also found out german kids greatly defeated me at memory games -should train more for next year! 🤭)
Memory games are also popular - PhD student Gina Dimari and my colleague Ellen Adams are warming up at the board
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