Don Moxley (@DonMoxley) profile picture
Joined January 2026
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4/ Men: one small trial saw testosterone replacement raise HRV in men with low levels. Steroid users at far higher doses showed lower vagal HRV. Dose appears to matter.
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5/ Training is the most consistent lever. Eight weeks of moderate aerobic work raised every HRV measure in 88 postmenopausal women, with or without hormone therapy.
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3/ Women: 16 women on estrogen saw menopausal symptoms drop sharply in one month while HRV held steady. Snapshot studies favor estrogen for vagal tone. Trials that follow women over time are mixed.
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1/ Hormone therapy and HRV training are two separate levers on your recovery system. The research shows they mostly move HRV on their own paths. Here’s what that means in the second half of life. 🧵
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2/ HRV (heart rate variability) is the beat-to-beat change in your heart’s timing. Much of it reflects the vagus nerve, your rest-and-recover pathway. Above your own normal usually means stronger recovery input.
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