Do stuff with T cells
Joined March 2021
- Tweets65
- Following208
- Followers120
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Edward Jenkins retweeted
NEW: @ImmunityCP study from the @DavisLab_Oxford, @CornallLab and @KlenermanLab uncovers how antibodies trigger immune receptors & provides a framework for designing better therapeutic antibodies for cancer & autoimmune diseases.
Read the full story here: bit.ly/498KFEB
ALT An illustration showing the surfaces of two cells coming together, with one at the top of the image and one at the bottom. A purple molecule protruding downwards from the top 'cell' and a green molecule protruding upwards from the bottom 'cell' are both bound to the same yellow molecule in the middle of the image. A red molecule protrudes downwards from the surface of the bottom cell. There is a large blue molecule to the right of the image that can't 'fit' between the two 'cells' where the interaction with the yellow molecule is occurring.
Edward Jenkins retweeted
Finally!!! It's been a long time coming, but it's hopefully a great read :D Thanks to everyone in Simon Davis and Dave Klenermans group. it's been fantastic!
sciencedirect.com/science/ar…
Edward Jenkins retweeted
Our new work is now published in @embojournal
embopress.org/doi/full/10.10…
Our new work!
Using CombiCells, a platform enabling titration and combinatorial display of cell surface ligands, to investigate the sensitivity and costimulatory requirements of TCRs and CARs
biorxiv.org/content/10.1101/…
Edward Jenkins retweeted
I'm thrilled to announce that our paper about ADAM10-mediated mucin shedding on apoptotic T cells has been released! Massive thanks to all who contributed on the way. Go check out the preprint here: lnkd.in/ggNaJkxK
Edward Jenkins retweeted
If you're interested in doing a PhD, postdoc or looking for an RA position in Germany doing fun microscopy and cool immunobiophysics, have a look at my lab in Würzburg: lippert-lab.de
Edward Jenkins retweeted
We present a meso Oblique plane microscope.
A microprism below the sample tilts the sheet, improving resolution and sectioning with a low magnification objectives.
We analyzed blood flow in zebrafish embryos at 12Hz.
biorxiv.org/content/10.1101/…
Edward Jenkins retweeted
Solution structure and synaptic analyses reveal molecular mechanisms of T cell specific engagers biorxiv.org/content/10.1101/…
Edward Jenkins retweeted
We are looking for a talented scientist to join our team! We will study how post-translational modifications influence T cell communication in health and disease with an initial focus on cancer immunity.
my.corehr.com/pls/uoxrecruit…
Edward Jenkins retweeted
I am so excited to share our latest research – a fossil whale which may beat the blue whale to the title of heaviest marine animal ever! Say hello to Perucetus! 🇵🇪
Published today in Nature!
nature.com/articles/s41586-0…
Got a big itch to study T-cell exhaustion!!??
Our review has got your back! We include:
🙆The latest updates in exhaustion🙆
🧪In vivo/vitro models of exhaustion🧪
📊How to best verify in vitro exhausted T cells📊
📈The future of in vitro approaches📈
doi.org/10.1093/oxfimm/iqad0…
@SharmaSumana
@DavisLab_Oxford
@MFellermeyer
@ Toby Whitehead
Was an absolute joy writing this with the authors involved!
Edward Jenkins retweeted
Localization, tissue biology and T cell state — implications for cancer immunotherapy dlvr.it/SpsJ0y
Edward Jenkins retweeted
We are hiring! The glycocalyx is a highly dynamic structure composed of glycosylated immune receptors, RNAs and lipids. We are looking for a postdoctoral researcher to dissect the glycan synthesis and sensing pathways modulating T cell communication in cancer. See details here: lnkd.in/e2dCbS_U.
The video below shows the T-cell glycocalyx (magenta) rearranging after five minutes of stimulation over synthetic cancer cell membranes (green). Our lab at the @CAMS_COI_Ox aims to dissect key enzymes and sugars promoting or inhibiting specific receptor-ligand interactions needed for cancer rejection.
Edward Jenkins retweeted
Professor Michael Dustin FRS is elected a Fellow of the Royal Society. His interests are focused on cell-cell synapsis in the immune system. #RSFellows royalsociety.org/people/mich…
Edward Jenkins retweeted
Excellent effort, well done @samofmidworld, great to see it in preprint.
biorxiv.org/content/10.1101/…
Edward Jenkins retweeted
“We show that LaTeX users were slower than Word users, wrote less text in the same amount of time, and produced more typesetting, orthographical, grammatical, and formatting errors. “
journals.plos.org/plosone/ar…
Thanks @FlorianBuehler
Edward Jenkins retweeted
Re: the history of the DNA structure, see this blistering 1967 letter from Crick to Watson objecting to the draft of Watson’s book on their work. “...it shows such a naive and egotistical view of the subject as to be scarcely credible.” profiles.nlm.nih.gov/spotlig…
Edward Jenkins retweeted
We did a thing, you can read about it here, tinyurl.com/4bayz4y8. Well Done @Markus_Koer and @DrEdJenks!
Edward Jenkins retweeted
We are absolutely delighted that our PI Omer Dushek (@Dushek) has been shortlisted for a British Society of Immunology (@britsocimm) Research Excellence Award!
Congratulations Omer, and we have our 🤞 for a win at the awards ceremony!
immunology.org/news/bsi-immu…
