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Cleveland Clinic Head and Neck Pathology

@ENT_Path

We evaluate more than 4,000 specimens each year, encompassing a wide spectrum of consultation cases (link for info - https://teapawt.net/t.co/3Ohr2s0Ioa). Managed by @HNPathology

 Cleveland Clinic,Cleveland,OH
my.clevelandclinic.org/departments/pathology/depts/pathology/head-neck
Joined January 2020
  • Tweets14
  • Following31
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This last case was a tricky example of an oncocytic variant of salivary duct carcinoma (see HE with AR IHC in same area). Pos IHC: GATA3 and PanK; Some neg IHC: S100 and p63 @HNPathology @golgigriff
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
Cleveland Clinic Head and Neck Pathology (@ENT_Path) profile pictureCleveland Clinic Head and Neck Pathology@ENT_Path29 Jun 2020
Parotid mass with multiple cervical lymph node mets. What is your DDX and what IHC would you order! @HNPathology
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
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Parotid mass with multiple cervical lymph node mets. What is your DDX and what IHC would you order! @HNPathology
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
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Thank you everyone for your thoughts! Excellent differential diagnoses were provided. The case is an example of an acantholytic SCC. P40+ IHC in the soft tissue deposit in the neck lymph node. @smlungpathguy @pathology @EntPathMan
Tumor arising in the tongue

ALT Tumor arising in the tongue

Transition areas from a differentiated component towards an acantholytic pattern

ALT Transition areas from a differentiated component towards an acantholytic pattern

P40 in the lymph node

ALT P40 in the lymph node

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"Neck mass" dissected during glossectomy. What is your DDX of this neck mass? Will share diagnostic IHC and primary tumor pictures tomorrow morning 🙂 #pathology #entpathology
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
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Polypoid vocal cord lesion. Look carefully in this exuberant epithelial proliferation! Diagnosis? #entpath #pathology
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
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Examples of perineural invasion in different glossectomies.
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
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NUT Midline CA (IHC: NUT antibody+)
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
Image from Cleveland Clinic Head and Neck Pathology (@ENT_Path)
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One of our posters at #USCAP2020 - PAX8 has inconsistent expression in cribriform-morular variant of papillary thyroid carcinoma #pathology #entpath #medicine #thyroid
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