'E-cigarettes have failed to achieve their initial goals—both from a scientific and a health care perspective. Realistically, tobacco/e-cigarette companies have fully achieved their goals. Although the number of tobacco smokers declined, the number of e-cigarette users has exploded. So many people changed their nicotine delivery devices and so many more became addicted. At the end, we have 1 winner, the tobacco/e-cigarette companies, and millions of losers, the addicted. There will be even more e-cigarette users in the coming years, as they believe they are consuming the healthier alternative' ahajournals.org/doi/10.1161/… @atvbahajournals