Postdoc @RIKEN_BDR studying skin ECM & aging, prev. PhD @narita_lab senescence & p53. (BA, MSci & RA) @CamBiochem @Peterhouse_Cam, @SheekeyScience YouTuber
Kobe, Japan
Joined June 2013
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The future of scientific research is here.
Recently, I was fortunate to speak with @brian_armstrong & @joycesticks about @ResearchHub - a platform to upload/discuss science papers. Brian also shares details on @newlimit!
--> youtube.com/watch?v=1FmhHLPr…
#scicomm #AcademicYouTube
Researchers engineered an enzyme to reverse CML, an advanced glycation end product considered an irreversible marker of aging.
In this video, I breakdown the findings and give my thoughts!
youtu.be/fGjWaC5ZnPI
AI can now design antibodies to hit a target you pick — no animals, no massive screens.
I spoke with @santimillef to unpack Germinal, the open-source pipeline behind it.
We discuss how it works, the bottlenecks and what's next :
youtu.be/g9GBoiOtibQ
Eleanor Sheekey retweeted
thank you, @EleanorSheekey for your questions and @agingdoc1 for spreading the link.
Here lifespan.io/news/playing-the… and here biorxiv.org/content/10.1101/… are the popular and academic versions of the narrative discussed on the podcast.
Friends, help please, as usual, spread the story with your likes and reposts. It's a lot better having a bad theory than none at all - let's get to the core of this.
How We Should Target Aging | Peter Fedichev
Love what @EleanorSheekey is doing with @SheekeyScience. One of the sharpest geroscience #scicomm channels around, and @fedichev always brings the fire 🧪
youtube.com/watch?v=buEPyBiK…
Are we targeting aging the wrong way?
In this interview with Peter Fedichev (@fedichev), CEO of Gero, we discuss why many longevity interventions may only be tackling “level 1” aging.
youtu.be/buEPyBiKrXw
Eleanor Sheekey retweeted
🎉 Congrats to #AGE2026 Early Career Scholar Awardee Eleanor Sheekey (@BDR_RIKEN)!
Recognized by the #AmericanAgingAssociation, her research studies how the extracellular matrix shapes cellular rejuvenation — uncovering how tissue environments influence aging and regeneration.
Eleanor Sheekey retweeted
Nice summary, thank you!
Please help with likes and reposts!
It turns out with a bit of physics, you don't need 300 theories to explain aging—just 3 variables.
In this video I show how this model can be used to categorise longevity interventions into 3 distinct levels based on their potential to extend lifespan.
youtu.be/c-_Pdp5IIvw
It turns out with a bit of physics, you don't need 300 theories to explain aging—just 3 variables.
In this video I show how this model can be used to categorise longevity interventions into 3 distinct levels based on their potential to extend lifespan.
youtu.be/c-_Pdp5IIvw
Eleanor Sheekey retweeted
For anyone interested in longevity-related research/therapies, this video is definitely worth a watch!
Eleanor Sheekey retweeted
FOXO3-modified cells reversed aging phenotypes in primates this year—cognitive decline, osteoporosis, fibrosis, infertility.
VitaDAO is funding FOXO3 research targeting degenerative disc disease.
@EleanorSheekey's full 2025 longevity breakthroughs breakdown: youtube.com/watch?v=X-Hzyzo1…
This year’s biggest breakthroughs in longevity are now up !!
youtu.be/X-Hzyzo1Jpk
Eleanor Sheekey retweeted
Exciting news: the Public Longevity Group was featured on the Sheekey Science Show!
@shoseph spoke with @EleanorSheekey about how PLG is building the first cultural intelligence system for longevity and why public trust is the real bottleneck.
Watch: youtube.com/watch?v=bnUPDSe-…
Eleanor Sheekey retweeted
理研のEleanor(@EleanorSheekey )さんによる「Cells vs. the ECM: who's in charge of tissue aging?」の講演となります。
ECMの老化に関するお話になります。
第2部では、交流会となりますので、奮ってのご参加をお待ちしております。
ALT 発表タイトル：Cells vs. the ECM: who's in charge of tissue aging? 発表者：Eleanor Sheekey/ (RIKEN, BDR, PostDoc) 概要：As we age, not only do cells age, but changes also occur in the ECM. The question remains - which is more dominant in the aging process? Using novel functional reconstitution assays that pair young cells with aged ECM and vice versa, we're testing whether cellular youth or matrix vitality exerts stronger rejuvenating effects. In this talk I will introduce ECM aging and explain in detail my experimental approach to address this question.
Eleanor Sheekey retweeted
had fun chatting w/ @EleanorSheekey about our recent announcement and @RetroBio_ (link below)
Eleanor Sheekey retweeted
🚨Only a few days left to apply to join our lab working on senescence and cancer research at the University of Cambridge @Cambridge_Uni CRUK CI @CRUK_CI 🚨
Info below for informal enquiries:
jobs.cam.ac.uk/job/52026/
jobs.cam.ac.uk/job/52027/
Eleanor Sheekey retweeted
Just dropped! 🎉 Had a blast on @SheekeyScience The Sheekey Science Show with @EleanorSheekey discussing how @KiraGenBio is using gene editing + ML‑powered CAR‑T to tackle deadly solid tumors like GBM. Dive into our origin story and vision! 🧬🎧
Link: youtu.be/OMOCa8DmJxQ
Eleanor Sheekey retweeted
Thank you @EleanorSheekey for inviting me to the show!
It was fun discussing the stochasticity of aging and potential remedies with you.
Watch the whole episode 👇
youtu.be/Buj07nWt7o0
If you are interested in more details: 🧵 (1/7)
#Aging
#Longevity
Eleanor Sheekey retweeted
@SheekeyScience breaks down the @ShiftBioscience preprint 'A single factor for safer cellular rejuvenation' highlighting both the progress and caveats. Thanks @EleanorSheekey for opening up the frontlines of cell rejuvenation to a larger audience! youtube.com/watch?v=cH_Igeb5…
Eleanor Sheekey retweeted
🔜 In less than a month, we're heading to sunny California to co-host the Longevity Science Conference @ Vitalist Bay (@VitalistBay), bringing together some of the top scientists, biotech leaders, and innovators in our network to explore, discuss, debate, and progress the latest in longevity R&D.
Agenda:
Expect short, impactful talks, hands-on workshops, and open discussions covering...
🔸 Biomarkers of aging - from discovery to application
🔸 Partial reprogramming & cellular rejuvenation - rethinking biological clocks
🔸 Damage repair & gerotherapeutics - interventions to extend healthspan
🔸 Clinical translation & regulatory hurdles - accelerating pathways to market
🔸 And more, including ethics, innovation, and emerging trends
Why Attend:
🛠️ Join workshops to turn cutting-edge research into real-world applications.
🤝 Network with leading minds from biotech, academia, and investment including: Michael Conboy, Peter Fedichev (@fedichev), Yuri Deigin (@ydeigin), Vera Gorbunova, Martin Borch Jensen (@MartinBJensen), Caitlin Lewis, Matthew "Oki" O'Connor, Kevin Perrott (@kevinperrott), Nathan Price (@NathanPriceSci), Marco Quarta (@MarcoQuarta12), Mahdi Moqri (@mahdi_moqri), Eleanor Sheekey (@EleanorSheekey) Alan Tomusiak (@alantomusiak), Keshav K Singh (@mitoscientist), Daniel Ives (@dives86) and more to TBA soon.
🫂 Enjoy and part-take in debates on the future of longevity science and its ethical considerations... things may get spicy 🌶️
☀️ Great weather, like-minded folks, and great ideas.
📍 Location: Vitalist Bay, Berkeley, CA
🗓 Dates: April 12-13, 2025
🚨 Exclusive discount for our community: $150 off with code BOA150...
🎟 Tickets: vitalistbay.com/longevity-sc…
Join us for a wonderful experience at the intersection of longevity research and its translation. See you in Berkeley!
CC: Adam Gries (@adamgries), Nathan Cheng (@realNathanCheng), Longevity Biotech Fellowship (@LBF_org), Vitalism Foundation (@vitalismorg)
