@EmmaEBoxer

Cell types, circuits || mood, motivation, stress. Study females, too!

 Pasadena, CA
Joined December 2018
  • Tweets152
  • Following357
  • Followers188
4Media
Hi, my Paper with @Aoto_Lab is Published! Very excited to share our work in which we identify ventral subiculum (a very cool but understudied region of ventral hippocampus that regulates reward and stress) as a sexually... cell.com/cell-reports/fullte… (1/4)

Neurexin-3 defines synapse- and sex-dependent diversity of GABAergic inhibition in ventral subiculum

While the diverse role of neurexins at hippocampal excitatory synapses is becoming more clear, the function of neurexins at hippocampal inhibitory synapses is less well known. Boxer et al. reveal...

cell.com
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Sardines: Pound for pound the most nutrient dense fish on the planet An 80/20 health food at its finest Bless yourself in 7 ways by eating these bad boys 1-3x per week THREAD
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Our paper is out! Ventral subiculum output to NAc exhibits a D2R bias and has distinct synaptic properties from vCA1 output. Cocaine withdrawal potentiates vSUB-D2R synapses.
Aoto Lab@Aoto_Lab16 Feb 2023
Emma Boxer's (@EmmaEBoxer) and JungMin Kim's (@jungminKimwipes) study investigating the unique synapse-specific properties of ventral subiculum output to D1R and D2R MSNs in dorsal NAc medial shell is out now in @SfNJournals! jneurosci.org/content/43/7/1…

Ventral Subiculum Inputs to Nucleus Accumbens Medial Shell Preferentially Innervate D2R Medium...

Ventral subiculum (vSUB) is the major output region of ventral hippocampus (vHIPP) and sends major projections to nucleus accumbens medial shell (NAcMS). Hyperactivity of the vSUB-NAcMS circuit is...

jneurosci.org
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Emma E Boxer retweeted
Aoto Lab@Aoto_Lab6 Jan 2023
Emma Boxer's (@EmmaEBoxer) review article is now out in @FrontNeurosci! She covers our current understanding about the functional roles neurexins and their ligands have at inhibitory synapses.
Frontiers - Neuroscience
@FrontNeurosci3 Jan 2023
New Research: Neurexins and their ligands at inhibitory synapses: Since the discovery of neurexins (Nrxns) as essential and evolutionarily conserved synaptic adhesion molecules, focus has largely centered on their functional… frontiersin.org/articles/10.… #Synaptic #Neuroscience
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We are excited to share our new work @Nature, led by @Lenka_Dohnal, uncovering a gut-brain pathway that regulates the motivation for #exercise. (1/7) nature.com/articles/s41586-0…
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Proactive vs Reactive Aggression are driven by unique circuits. Mounting for Sex/Mating vs Mounting for Dominance are separable too. More here: hubermanlab.com/dr-david-and…

Dr. David Anderson: The Biology of Aggression, Mating & Arousal

Dr. David Anderson: we discuss how states of mind (and body) arise and persist and how they probably better explain human behavior than emotions per se.

hubermanlab.com
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New Huberman Lab Podcast Out Now: THE BIOLOGY of MATING, AGGRESSION, FEAR & OTHER MOTIVATED BEHAVIORS. • Aggression-Mating Combo Circuits • Mounting in Sex vs Pure Dominance • Pro- & Anti-Anxiety Peptides • Estrogen Drives Aggression • Fetishes hubermanlab.com/dr-david-and…

Dr. David Anderson: The Biology of Aggression, Mating & Arousal

Dr. David Anderson: we discuss how states of mind (and body) arise and persist and how they probably better explain human behavior than emotions per se.

hubermanlab.com
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Emma E Boxer retweeted
Aoto Lab@Aoto_Lab6 Jun 2022
Faculty and student (@EmmaEBoxer) research excellence awards from @AMCPharmacology. @CUAnschutz Dean's Doctoral Mentoring Award (2022). Thanks to all current and former Aoto Lab members for their nomination and support letters for the mentoring award!
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2022 Awards Announced! Jason Aoto, PhD (@Aoto_Lab) receives @CUDenverGS Dean's Doctoral Mentoring Award 🏆 graduateschool.ucdenver.edu/…
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The brain is absolutely crazy.
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huge congrats to @candelabellot for her paper just out in @NatureComms! She found two distinct populations of hippocampal neurons that project to PFC, that have distinct influence on PFC circuitry and opposite effects on behaviour! @uclnpp @uclbiosciences nature.com/articles/s41467-0…
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Emma E Boxer retweeted
SfN Journals@SfNJournals6 Jan 2022
How is taste info encoded? #JNeurosci research reconstructing the synaptic circuitry of taste buds from @courtthewilson et al @taste_and_smell @CUAnschutz, find that taste cannot entirely be carried along nerve fibers dedicated to single taste qualities. jneurosci.org/lookup/DOI/10.…
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Most people think of hippocampal ACh as important for memory encoding or attention, but first we confirm using GRAB-ACh many microdialysis studies showing that stressors induce ACh release in hippocampus (see published data from @TjShors and others)
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LTP NOT the cellular correlate of learning and memory… 😱
This Post is from an account that no longer exists. Learn more
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TIL Cheerios changed its name from Cheery Oats Bc Quaker Oats filed for trademark infringement for the use of “oats” in the name (?)… also Sylvia Plath considered it a garbage breakfast choice
Sylvia Plath's Food Diary@whatsylviaate20 Dec 2021
For breakfast most people eat eggs or oatmeal or cold cereal. It is called by various silly names such as “Rice Krispies” and “Cheery Oats” and it always tastes the same - like little pieces of pressed hay or sawdust. 12/20/48
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We found that this connectivity is directed in part by the presynaptic adhesion molecule, Neurexin-3, which we reveal exhibits synapse- and sex-specific functions at vSUB PV synapses. Interesting implications for understanding the sex differences observed in addiction, (3/4)
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schizophrenia, and depression, which exhibit alterations in vSUB activity in rodents and humans, and are associated with Nrxn3 mutations. Thank you to my twitterless co-authors for critical help with imaging and scRNAseq and to our reviewers. (4/4)
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Emma E Boxer retweeted
Cathy Chen@banditcathy23 Nov 2021
So excited to have this work out! Ready for more sex difference stories? Check out our new paper on eLife! elifesciences.org/articles/6… Big thanks to my advisor @NicolaGrissom, our awesome collaborator @BecketEbs, my colleagues @EvanKnep and everyone in lab!

Sex differences in learning from exploration

A new computational analysis of decision making in mice shows sex biases in value-updating while exploring unknown options, with male mice tending to explore longer than females due to updating...

elifesciences.org
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