Coiled Coil Molecular Dynamics & Design @EdinburghChem | @EastbioDTP PhD researcher at @julienmich80 and @ChrisWellsWood labs
Joined February 2021
- Tweets53
- Following130
- Followers79
- Likes336
Eva Notari retweeted
Round two! The Apheris x Wells Wood Lab have been busy (again!). Here are our 40 submissions for the TNF-α challenge of the @adaptyvbio x @AnthropicAI
Protein Design Competition!
GLP-1 next!
I’m told hashtags are still a thing:
#ProteinDesign #OpenScience #AI #Apheris #adaptyv
Eva Notari retweeted
The Apheris x Wells Wood Lab (Christopher Wood) has been hard at work designing proteins! Heres a video of our submissions for the first @adaptyvbio x @AnthropicAI Protein Design Competition!
Stay tuned for TNF and GLP-1!
Eva Notari retweeted
Coxon Lab (Edinburgh) reports hydrocarbon‑stapled peptides targeting the CGRP receptor, enhancing stability & maintaining activity, advancing the design of metabolically robust peptide therapeutics. #JMedChem
go.acs.org/dTY
Eva Notari retweeted
Wells Wood Lab protein design landed in top 1.2% in Adaptyv Nipah Virus Protein Design Competition in which 680+ participants submitted over 10,000 designs.
This was a great team effort with @EvaNotari, @DrLeucine , @mjstam, and @s_mert_unal @ChrisWellsWood
Eva Notari retweeted
All designs were scored with MD magic from @EvaNotari and our very own "Stam score" (@mjstam ), and we filtered out any candidates that showed non-specific co-folding.
Fingers crossed for the lab experiments!
Eva Notari retweeted
We (@ChrisWellsWood Wood's lab) have taken the lead at the @adaptyvbio competition against the Nipah Virus!
Give us your ⭐️ for our other designs here:
proteinbase.com/collections/…
Eva Notari retweeted
We are pleased to announce drMD: Molecular Dynamics for Experimentalists!
Read the paper at:
sciencedirect.com/science/ar…
Get the code from:
github.com/wells-wood-resear…
#proteins #moleculardynamics
Eva Notari retweeted
New Communication out NOW from @CampopianoGroup, @ArtOxiZymes, @jarvis_lab, @EdinburghChem
#openaccess
'Installation of an organocatalyst into a protein scaffold creates an artificial Stetterase'
buff.ly/4i6EDsY
Eva Notari retweeted
Congratulations Alice and all involved! 📰🥼👩🔬
@ArtOxiZymes, @CampopianoGroup, @Brew_Richard, @ChrisWellsWood, @klemencic_eva, Mert and Evangelia
Congrats to Alice on publishing her PhD work in Chem Comm.
The first example of a NHC-modified protein displaying Stetterase activity!
Great work.
@ArtOxiZymes @EdinburghChem
pubs.rsc.org/en/content/arti…
Eva Notari retweeted
Congrats to Alice on publishing her PhD work in Chem Comm.
The first example of a NHC-modified protein displaying Stetterase activity!
Great work.
@ArtOxiZymes @EdinburghChem
pubs.rsc.org/en/content/arti…
Eva Notari retweeted
drMD: Molecular Dynamics for Experimentalists biorxiv.org/cgi/content/shor… #biorxiv_bioinfo
Last week I presented my research on predicting the oligomerisation states of coiled coil proteins with MD simulations at the annual Joseph Black conference organised by @EdinburghChem. Very pleased to have received an award for the best oral presentation in Physical Chemistry.
Eva Notari retweeted
New preprint out!🚨We performed a large scale analysis of physicochemical features extracted from over half a million AlphaFold structural models, and using data-driven methods we showed a link between these features and in vivo behaviour of proteins. Find out more below⬇️1/9
Large scale analysis of predicted protein structures links model features to in vivo behaviour biorxiv.org/cgi/content/shor… #bioRxiv
Eva Notari retweeted
🍻I will be giving a @pintofscience talk titled "How to Create a Protein" on May 14 in Edinburgh! 🍻
pintofscience.co.uk/event/re…
Eva Notari retweeted
#pint24 is live!
If in Edinburgh, come and join me at Bar50 on May 13 for a night of 🔬🧪🧬 and some 🍺🍺!
Sneak peek...I will talk about "kinetoplast DNA" 🧬🪢 and how bloodsucking parasites are tech-ing us out 👀
pintofscience.co.uk/event/te…
Eva Notari retweeted
If you're in #Edinburgh this May, why not pop along to @pintofscience to learn about some of the ways current research is revolutionising healthcare? Join us on May 14th for a 🍺 and some 🧪, and find out how I'm trying to make peptide drugs more sustainably! #pint24 #TechMeOut
Very happy to have collaborated with @AdamSchofield__ @Dr_CR_Coxon on optimising a HPLC focused gradient for peptide purification. Check our application note below🧪
Very happy to share an application note on generating a focused gradient for #peptide #purification using the @TeledyneLABS1 #ACCQPrep with water and acetonitrile (0.1% TFA) mobile phases. @EvaNotari @Dr_CR_Coxon
teledynelabs.com/en-us/resou…
Eva Notari retweeted
I had a fantastic experience in giving an oral and poster presentation at #PPSG2023 about new #migraine treatments. Very honoured to win best poster! Well done to everyone giving talks and posters today. Now let’s hope #StormBabet calms down so I can get home… @RSC_PPSG – at Bushey, East
Eva Notari retweeted
@EastbioDTP PhD opportunity ''Multifidelity simulations for high-throughput generative protein engineering pipelines'' collaboration with @DrStracquadanio @EdinburghUni findaphd.com/phds/project/ea…
Eva Notari retweeted
Applications are open for our EASTBIO PhD project: Peptide chemical tools to probe the role of the PrfA transcription factor in Listeria virulence at University of Edinburgh on FindAPhD.com #peptides @EurPepSoc @RSC_PPSG findaphd.com/phds/project/ea…