@FassLab

Oxidative protein folding and assembly; Molecular and structural take on #mucus. @ERC_Research funded. Tweets by Debbie signed DF.

 Weizmann Institute, Israel
weizmann.ac.il/CSB/Fass/
Joined February 2021
  • Tweets35
  • Following80
  • Followers198
Fasten your seatbelts because this semester brings an exceptional seminar series! 🤩 We have an amazing lineup of speakers for this seminar season at @biumedicine. 🤯🤯🤯
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Did you register yet to ABPP 2023??? 17-19/7/2023 Please RT! 🧪💥weizmann.ac.il/conferences/A… #ABPP #Proteomics #Covalent #BestMeetingEver
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Great talk by @NavaReznik (@FassLab ) at #ILANIT2023 💪
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Very excited to share our recent cool story! Commensal microbiota from patients with inflammatory bowel disease produce genotoxic metabolites science.org/doi/10.1126/scie…

Commensal microbiota from patients with inflammatory bowel disease produce genotoxic metabolites

Functional screening of commensal gut microbiota reveals small-molecule genotoxins in patients with inflammatory bowel disease.

science.org
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Congratulations to @DapingYang88 and lab members on our recent work, now on the cover of @CellCellPress! Glad to have this work out and excited to continue studying how neurons regulate barrier function and #immunology in the #gut and other sites authors.elsevier.com/c/1fv-7… – at Boston, MA
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New paper alert 🥳! Happy to share new study on epigenetic rewiring of CAFs @CR_AACR Global DNA Methylation Analysis of Cancer-Associated Fibroblasts Reveals Extensive Epigenetic Rewiring Linked with RUNX1 Upregulation in Breast Cancer Stroma! aacrjournals.org/cancerres/a… 1/6
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The disulfide catalyst QSOX1 maintains the colon mucosal barrier by regulating Golgi #glycosyltransferases @ilani_tal et al @FassLab @WeizmannScience embopress.org/doi/10.15252/e…
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#NatMetabPicks | In @CellCellPress, the @FassLab (@WeizmannScience) reveals a protective role of intestinal mucus, which prevents copper-related #toxicity through intestinal mucin, by acting as an extracellular copper chaperone. cell.com/cell/fulltext/S0092…

Intestinal mucin is a chaperone of multivalent copper

Mucins, the major constituents of mucus, protect cells by capturing copper and blocking generation of reactive oxygen species. A two-tiered site in intestinal mucin enables binding of copper in...

cell.com
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Fass Lab retweeted
Cell@CellCellPress6 Oct 2022
Now online! Intestinal mucin is a chaperone of multivalent copper dlvr.it/SZdXq4
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With the @FassLab expanding our #mucin knowledge listening to great talks @mucinmeeting 🤓 #mucin2022
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Check it out- Helical self-assembly of a mucin segment suggests an evolutionary origin for von Willebrand factor tubules #mucin2022 #mucusmatters pnas.org/doi/10.1073/pnas.21…

Helical self-assembly of a mucin segment suggests an evolutionary origin for von Willebrand factor...

The glycoprotein von Willebrand factor (VWF) contributes to hemostasis by stanching injuries in blood vessel walls. A distinctive feature of VWF is...

pnas.org
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Deborah Fass is taking a high resolution look at mucins at #mucin2022 #mucusmatters – at Utrecht, The Netherlands
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