Researching glia in neurodegeneration and ageing. We are based at Sheffield Institute for Translational Neuroscience (SITraN).
Sheffield, United Kingdom
Joined July 2019
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Take a moment to read our new findings on how endothelial cells forming the blood brain barrier can affect motor neurons in #mnd #als @AnaAragonG @neuroshef @ENeurotrophin fluidsbarrierscns.biomedcent…
The Ferraiuolo Lab retweeted
#BenevolentNews: Pleased to announce that we have progressed BEN-34712 into IND-enabling studies.
BEN-34712 is an oral, potent and selective brain penetrant RARɑ𝛃-biased agonist being developed for the potential treatment of #ALS.
Read more → benevolent.com/news-and-medi…
The Ferraiuolo Lab retweeted
Supporting studies that progress to this point and beyond is why I dedicated my life to neuroscience and #MND #ALS research. So proud to have worked on this with @Richard_Mead @FerraiuoloLab @benevolent_ai @neuroshef
#BenevolentNews: Pleased to announce that we have progressed BEN-34712 into IND-enabling studies.
BEN-34712 is an oral, potent and selective brain penetrant RARɑ𝛃-biased agonist being developed for the potential treatment of #ALS.
Read more → benevolent.com/news-and-medi…
The Ferraiuolo Lab retweeted
For those who needs to see some Striatal Medium Spiny Neurons in this beautiful sunny day.
Have a good weekend everyone.
#StemCell #neuroscience
The Ferraiuolo Lab retweeted
Thank you @pintofscience for hosting a great event! A great evening presenting our work with @MartynaMatuszyk @DrMarianneKing and Tania! As always the support from @FerraiuoloLab is amazing so proud to be a part of this team! ❤️ #PintOfScience #research #MND
Our embryoid bodies that we use for our cocultures are looking especially bright and green today! We should get beautiful motor neurons from these, which we will use to test different drugs to see if they can prevent the motor neurons from degenerating. #Cellfie #MND #MNDresearch
Some beautiful cells to brighten up your Saturday! Here we have some neuronal progenitor cells derived from induced pluripotent stem cells, stained for Pax6 and Nestin (NPC markers).
The Ferraiuolo Lab retweeted
Fantastic first talk delivered by @LauraFerraiuolo about modelling MNS in astrocytes. Very cleaver fast track differentiation from fibroblasts to cells of interests 💨🧫
The Ferraiuolo Lab retweeted
We have fantastic external speakers including @LauraFerraiuolo, John Greenman and Michele Zagnoni. We will also have our internal disease models experts speaking including @Basudha_Basu, Elizabeth Roundhill and @SalPeyman 🤩🤩🤩
The Ferraiuolo Lab retweeted
30 years ago today the first cause of #ALS #MND was found by Prof Robert H Brown Jr and his team. Now we have a genetic therapy, Tofersen, that looks to have a dramatic effect in the 2% carrying this gene variant. A small step that shows ALS can be defeated with the right tools.
Honoured to be part of this study that furthers our understanding and gets us closer to potential treatments for #MND A cell-penetrant peptide blocking C9ORF72-repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins science.org/doi/10.1126/scit…
The Ferraiuolo Lab retweeted
@MNDoddie5 @burrow_geoff . Could you please follow and retweet. We are attempting a world record to raise funds and awareness of MND. sthelensstar.co.uk/news/2332…
Friday in the lab: neurons are @CleideNeuro's priority, everyone else can wait.
Photo courtesy of @DrMarianneKing.
Well done All! Great job @Raquel_RMartins
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The Ferraiuolo Lab retweeted
Happy to share an online entry about "Components of the Blood–Brain Barrier", adapted from our recent review article doi.org/10.3390/ijms23231527… ,
at the free and open platform for researchers @EncyclopediaMD1
encyclopedia.pub/entry/40721
🧠Go have a look!
@FerraiuoloLab
#OpenScience
Happy New Year from all of us at Ferraiuolo lab! Here's to a great 2023.
If one of your New Year's resolutions is to keep abreast of our work, our website is a great place to start.
theferraiuololab.com/publica…
Great to have our very own @AstroMysz attend and present at the #morethanneurons meeting in Turin @neuroshef @mndresearch
