@Foldit

Foldit is a free scientific discovery game that lets you to contribute to important biochemistry research. 🎮 🧬 Join our Discord! https://xitter.cf/t.co/e5OdzvAZ7n

 University of Washington
fold.it
Joined June 2009
  • Tweets1.6K
  • Following32
  • Followers4.1K
229Media
Ready to learn about protein design? Our beginner's guide breaks down this complex field into easy-to-understand concepts. Discover the potential of proteins to transform our world: ipd.uw.edu/2023/05/what-is-p…
An artist’s depiction of a protein structure emerging from a computer chip.

ALT An artist’s depiction of a protein structure emerging from a computer chip.

45
4
164
35,863
Introducing The Gameful Scientist! I'm excited to explore the intersection of science and gaming to reimagine how discoveries are made. thegamefulscientist.substack…
6
19
4
75
16,506
This week's #GameOfTheWeek is Foldit! @Foldit explores the process living beings create the primary structure of proteins. Foldit is an attempt to apply the human brain’s natural three-dimensional pattern-matching abilities to this problem. Play now! buff.ly/3Bq3q8h
9
40
Today our admin team met with @RepJayapal to celebrate new Federal investments in 10 key projects across the Seattle area. Our request will enable the purchase of advanced laboratory equipment that will help us discover new cures for current and future pandemics.
Congresswoman Pramila Jayapal speaks at a podium in Seattle.

ALT Congresswoman Pramila Jayapal speaks at a podium in Seattle.

Congresswoman Pramila Jayapal hands an enlarged check for $550,000 to a team from the University of Washington Institute for Protein Design. The funding will support the purchase of advanced research equipment.

ALT Congresswoman Pramila Jayapal hands an enlarged check for $550,000 to a team from the University of Washington Institute for Protein Design. The funding will support the purchase of advanced research equipment.

2
13
3
65
When COVID-19 hit, scientists at @UWMedicine joined forces to develop a protein-based vaccine. The vaccine, called #SKYCovione, has just been approved in South Korea with more approvals under review. Now the team is working to create universal vaccines to stop all variants.
1
14
2
41
Protein structure via @Foldit #biochemistry
1
9
The COVID19 vaccine developed by @KingLabIPD & @VeeslerLab has met its Phase 3 trial goals and is now under review for full authorization in Korea. SK bioscience, the company leading clinical development abroad, found the vaccine outperformed Oxford/AstraZeneca’s in the clinic.
The vaccine, now called SKYCovione, is a tiny ball of protein studded with 60 copies of the SARS-CoV-2 receptor-binding domain (shown in red). Image: Ian C Haydon / UW Medicine Institute for Protein Design

ALT The vaccine, now called SKYCovione, is a tiny ball of protein studded with 60 copies of the SARS-CoV-2 receptor-binding domain (shown in red). Image: Ian C Haydon / UW Medicine Institute for Protein Design

1
35
8
99
Learning so much from this Protein Design and Foldit Webinar hosted by @iubmb_trainee! I'm really intrigued by the application of molecular logic gates in disease diagnostics and drug delivery. Thank you to Dr. David Baker for such an engaging and informative session. @iubmb
9
1
18
"Baker and his colleagues tested their strategy on 12 target proteins. [T]he researchers wound up with miniproteins that bound as strongly as, if not stronger than, most antibodies do." science.org/content/article/…

Software-designed miniproteins could create new class of drugs

Small versions of antibodies bind to virtually any target protein

science.org
1
36
2
129
This week's featured scientist is Odessa Goudy, a computational protein engineer!💻🧫 Odessa is a fifth-year Biochemistry and Biophysics PhD candidate in the Kuhlman lab at UNC. Odessa is also a co-founder of our organization! FoldIt Video: youtube.com/watch?v=lGYJyur4…
1
8
1
22
The IUBMB Trainee Initiative is excited to announce our first event: an online webinar about protein design, including a talk from Prof. David Baker and Dr. Brian Koepnick! More details and a registration link to follow soon! @Foldit @UWproteindesign @UWBiochemistry
3
20
4
35
"Protein Designer" is a futuristic job i wanted to write about in a sci-fi story, but apparently it's a real job now (thanks to AlphaFold & other works) and not sci-fi anymore.
Foldit@Foldit1 Feb 2022
We're making #AlphaFold even better in Foldit! We're launching a new tool that let's you see the parts of a protein that are most likely to fold — and the parts that still need work. WATCH: youtube.com/watch?v=5j4h20DI…
1
6
22
Just as convincing images of cats can be generated using artificial intelligence, new proteins can now be made using similar tools. In a new report in @Nature, we describe a neural network approach for “hallucinating” proteins with new, stable structures. nature.com/articles/s41586-0…
2
66
10
250
For decades, scientists working on a cure for AIDS were stumped by the structure of an enzyme. This enzyme was related to a virus similar to HIV. Learning its structure could mean a breakthrough in finding a cure. But they were stuck. The solution? An online game. (1/3)
2
15
2
33
David Baker is a 1994 Packard Fellow and biochemist at @UW who engages #citizenscientists to help protein researchers create novel vaccines, cancer therapies, & more using an online game called @Foldit. #PackardFellows #FellowsIsland 🏝 Learn more here: bit.ly/3nOexSa
1
8
21
S. Korea has just approved a Phase 3 trial of the COVID nanoparticle vaccine we reported last year in Cell: cell.com/cell/fulltext/S0092… All Phase 1/2 trial participants induced neutralizing antibodies. @KingLabIPD @veeslerlab @UWMedicine reuters.com/world/asia-pacif…

Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for...

Walls et al. describe a potential nanoparticle vaccine for COVID-19, made of a self-assembling protein nanoparticle displaying the SARS-CoV-2 receptor-binding domain in a highly immunogenic array...

cell.com
5
43
16
142
“What if people with no formal experience in science could help to improve or even rewrite nature, simply by playing a game?” Protein Data Bank updates us on @Foldit, a CS game for citizen scientists to help design new proteins. bit.ly/3x9CUKW @sethecooper @buildmodels

PDB101: Molecule of the Month: Designed Proteins and Citizen Science

What if people with no formal experience in science could help to improve or even rewrite nature, simply by playing a game?

pdb101.rcsb.org
6
11
A big day for 3D protein structure prediction via #AI deep learning. Down to atomic accuracy w/ open-source code, methodology @nature @ScienceMagazine @DeepMind @UWproteindesign @demishassabis @UWBiochemistry nature.com/articles/s41586-0… science.sciencemag.org/conte…
11
308
28
918
Just out in @ScienceMagazine: @UWproteindesign-led researchers present RoseTTAFold – a neural network approach for protein modeling with accuracies near those of what DeepMind’s AlphaFold2 has achieved. The tool’s code is freely available. science.sciencemag.org/looku…
6
189
22
641
The COVID-19 projects on our platform are headed into human clinical trials! Our amazing online volunteers have played a role in the development of a promising new vaccine as well as candidate antiviral treatments. From the whole team at @UWproteindesign, THANK YOU! (1/2)
12
48
5
102
Load more