Fortwendel Lab (@FortwendelLab) profile picture

Fortwendel Lab

@FortwendelLab

We are focused on delineating novel molecular mechanisms underpinning antifungal resistance and pathogenic fitness in filamentous fungal pathogens.

 Memphis, TN
Joined March 2012
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  • Following183
  • Followers165
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Photo by Fortwendel Lab (@FortwendelLab)Photo by Fortwendel Lab (@FortwendelLab)Photo by Fortwendel Lab (@FortwendelLab)Photo by Fortwendel Lab (@FortwendelLab)Photo by Fortwendel Lab (@FortwendelLab)Photo by Fortwendel Lab (@FortwendelLab)Photo by Fortwendel Lab (@FortwendelLab)Photo by Fortwendel Lab (@FortwendelLab)Photo by Fortwendel Lab (@FortwendelLab)Photo by Fortwendel Lab (@FortwendelLab)
Now hiring a postdoc in my lab at St. Jude! Looking for motivated candidates interested in mycology, CRISPR technologies, and advancing the treatment of patients with invasive fungal infections (C. auris, A. fumigatus, and Mucorales). Apply now: talent.stjude.org/careers/jo…
Image from Jeffrey M. Rybak PharmD, PhD (@Rybak_JM)
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Congrats to Jinhong Xie on her first author publication out today in Nature Comm- showing the Aspergillus sterol methyl-transferase, Erg6, associates with lipid droplets, is essential, and when repressed reduces mortality in a murine aspergillosis model!! nature.com/articles/s41467-0…
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Excited to share a recent publication in Nature Communications from our great team of investigators where we reveal a previously unknown secondary mechanism of action of the triazole antifungals against Aspergillus fumigatus mediated by Hmg1 nature.com/articles/s41467-0…
A secondary mechanism of action for triazole antifungals in Aspergillus fumigatus mediated by hmg1

A secondary mechanism of action for triazole antifungals in Aspergillus fumigatus mediated by hmg1

Nature Communications - Triazole antifungals are widely used and exert their action by inhibiting ergosterol biosynthesis. Here, Rybak et al show that these drugs both inhibit ergosterol...

nature.com
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That's a wrap on Day 3 of #AAAM24! 🎉 What an incredible journey through cutting-edge research and expert discussions. A huge thank you to our committee, faculty, speakers, attendees and everyone who made #AAAM24 a success. 🙌 Up next... #AAAM26! 📆 @dwdenning @gangneuxjp
Image from Advances Against Aspergillosis and Mucormycosis (@AAAMConference)
Image from Advances Against Aspergillosis and Mucormycosis (@AAAMConference)
Image from Advances Against Aspergillosis and Mucormycosis (@AAAMConference)
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Fortwendel Lab retweeted
Xabier Guruceaga (@XabiGuru) profile picture
Xabier Guruceaga@XabiGuru26 Jan 2024
Our last paper is out!!! Congratulations to all the authors from @microbiomicsEHU and @FortwendelLab, proud of you guys!!!! Read it here: frontiersin.org/articles/10.…
Frontiers | The Aspergillus fumigatus maiA gene contributes to cell wall homeostasis and fungal...

Frontiers | The Aspergillus fumigatus maiA gene contributes to cell wall homeostasis and fungal...

In this study, two distinct in vitro infection models of Aspergillus fumigatus, using murine macrophages (RAW264.7) and human lung epithelial cells (A549), w...

frontiersin.org
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An enlightening talk from @RobinaAerts at #AAAM24 goes to show the importance of effective science communication! A brilliant way to start #AAAM24 - well done 🙌
Sarah Dellière is on Bluesky 🦋 (@sarah_delliere) profile pictureSarah Dellière is on Bluesky 🦋@sarah_delliere25 Jan 2024
Take a subject with a high headache potential, give it to @RobinaAerts, get a a clear, thorough and entertaining talk… on PoC in aspergillosis 👏 ! #AAAM2024
Image from Sarah Dellière is on Bluesky 🦋 (@sarah_delliere)
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Dive into the realm of diagnostics at #AAAM24! 🕵️‍♂️ Session 3: "New Diagnostics for Aspergillosis, or Old Diagnostics in New Clothes?" is starting soon. @RobinaAerts, @IbrahimLab3, Xiao Liu, and @Inderpaul39 share insights. 🧪🔍 #MedicalInnovation #mycology
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Check out the line-up for session 11 of #AAAM24! This session boasts some exciting quick-fire discussions around fumigatus mycotoxins, chaired by @dwdenning and Anna Huttenlocher. Register to hear from the experts 👉 aaam2024.org/registration/ #fungal #mycology #conference
Image from Advances Against Aspergillosis and Mucormycosis (@AAAMConference)
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Join us on the cutting edge of medical mycology! 🔬 Harrison Thorn from @uthsc is set to unravel secrets on Aspergillus fumigatus Echinocandin Resistance and Virulence at #AAAM24. 🍄 Registration is still open 👉 ow.ly/bQEX50Qt02b #MedicalMycology #HealthcareConference
Image from Advances Against Aspergillosis and Mucormycosis (@AAAMConference)
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Thanks to all the people that participated in this work! Was great to work with you Ziortza, @XabiGuru, Adela, Ainara, Ane, @FortwendelLab and Eduardo. Identification and functional characterization of the putative... | mBio journals.asm.org/doi/10.1128…
Identification and functional characterization of the putative members of the CTDK-1 kinase complex...

Identification and functional characterization of the putative members of the CTDK-1 kinase complex...

Aspergillus fumigatus has been included by the World Health Organization in the priority list of fungal pathogens because (i) it causes 90% of invasive aspergillosis cases, with a high mortality...

journals.asm.org
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Diversity and biotechnological potential of filamentous fungi isolated from sediments of Basque estuaries biorxiv.org/cgi/content/shor… #biorxiv_micrbio
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Check our last preprint, in collaboration with @XabiGuru and Adela Martin-Vicente, from @FortwendelLab. And of course, with Eduardo Espeso from CIB Margarita Salas. A pleasure! biorxiv.org/content/10.1101/…
Identification and functional characterization of the putative members of the CTDK-1 kinase complex...

Identification and functional characterization of the putative members of the CTDK-1 kinase complex...

The genus Aspergillus includes industrially, medically and agriculturally important species. All of them, as do fungi in general, disperse to new niches principally by means of asexual spores....

biorxiv.org
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Congratulations Dr. Guruceaga for the nice talk! #Afumigatus #XVCNME @guruceagax @FortwendelLab
Image from MicrobiomicsEHU (@microbiomicsEHU)
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@GibbonsGenomics @FortwendelLab @FungalSao collaboration! Lead by @ShuZhaoTw and @Adela_MV, we identify genes involved in the Aspergillus fumigatus Caspofungin paradoxical effect. Big contributions from Ana Cristina Colabardini, @DaRinker @LilianPereiraS6 bit.ly/3xg1axE

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journals.asm.org
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זה וואוו זה – at Israel
Eric Feigl-Ding (@DrEricDing) profile pictureEric Feigl-Ding
@DrEricDing12 Nov 2021
💡BEST. VIDEO. ALL. YEAR. Please share with friends how the mRNA vaccine works to fight the coronavirus. 📌NOTA BENE—The mRNA never interacts with your DNA 🧬. #vaccinate (Special thanks to the Vaccine Makers Project @vaccinemakers of @ChildrensPhila). #COVID19
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The Tennessee Fungal Pathogens group held their 5th annual retreat @evinsmill. Thanks to all of the trainees and PIs from the Fortwendel, Hole, Palmer, Peters, Reynolds, Rybak, & Rogers labs for the stellar science presented! #fungi #TFP
Image from TNFungalPathogens (@TNFungalPath)
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