Developmental biologist, mostly harmless. #DEE parent. Also [email protected] & @frogsquisher@mstdn.science website https://xitter.cf/t.co/MX7yKbQHym…
Dunedin City, New Zealand
Joined March 2018
- Tweets602
- Following406
- Followers361
- Likes2.8K
Caroline Beck retweeted
Congratulations to Alexander Matthews who has been awarded a Woolf Fisher Scholarship, to undertake his PhD studies using computational modelling to understand the neural responses to anxiety, at Cambridge University!
More in the @odtnews: odt.co.nz/news/dunedin/campu…
Caroline Beck retweeted
Exceptional grant opportunity for NZ/Australia based genetics students to access sequencing! Have a peek: genetics.org.au/student-gran…
Caroline Beck retweeted
What if you could deliver molecular tools directly into oocytes without microinjection? In our new paper, online today @Dev_journal (doi.org/10.1242/dev.202857), we introduce VitelloTag, a new cargo delivery tool to enable injection-free genome editing. 👇Read on for a short 🧵
Caroline Beck retweeted
I am looking for a post-doc to work on our @MBIEsci project on #phages for #biocontrol #microbiology #genomics #genetics @microtago @otago pls repost otago.taleo.net/careersectio…
Caroline Beck retweeted
Loss of ETS sites in the ZRS enhancer of Shh has been linked to limb reduction in snakes. Here is another example of independent ETS site mutations in the ZRS linked to fin reduction in some lungfishes. Congrats to all authors of this tour de force study! nature.com/articles/s41586-0…
Caroline Beck retweeted
Ban on gene technology outside lab to end rnz.co.nz/news/political/524…
Caroline Beck retweeted
Happy to share @AnastasiaLabud1 PhD paper now out in @Dev_journal 🐟🧬 Cohesin composition and dosage independently affect early development in zebrafish journals.biologists.com/dev/… - we show that cohesin 'amount' vs 'flavour' matters differently to zebrafish embryos!
Caroline Beck retweeted
It took more than a DECADE... but finally it’s published!!! It started as a CRAZY idea but after tons of hard work we built it: We hijacked the endogenous secretion systems of Toxoplasma gondii, a brain parasite, to deliver active proteins to neurons 👇
nature.com/articles/s41564-0…
Caroline Beck retweeted
1st Asian Xenopus Conference. November 24, 2024 (Sun) to November 26, 2024 (Tues). Osaka University, Osaka, Japan. Abstract Submission: September 30, 2024. 2024.xenopus-asia.org/ xenbase.org/xenbase/doNewsRe… #science #biology #devbio #xenopus #frogs
Caroline Beck retweeted
Excited to announce that GO has secured funding through 2028 as one of 14 @otago Research Themes!
Looking forward to continuing to support our community and bringing in some new initiatives too!
otago.ac.nz/news/newsroom/re…
Last Friday, many @Zoology_Otago staff and students gathered in the Benham Garage for a midwinter BBQ organised by Neuroscientists @BartGeurten and @PaulSzyszka. Good times, happy faces and many, many sausages..
Caroline Beck retweeted
PanelApp is our virtual #gene panel tool - free to share, view & download. Check it out here: panelapp.genomicsengland.co.… #genomics
Looking forward to reading this from @hamishgspencer !
What do biologists mean by #sex? They should look to #evolution. @GeneticsOtago @Zoology_Otago @otago nature.com/articles/d41586-0…
Caroline Beck retweeted
We are looking for an Assistant Research Fellow to join the group and work on #phages as part of our @MBIEsci funded work. You must have right to live and work in NZ to be eligible. Details below otago.taleo.net/careersectio… please share
Caroline Beck retweeted
Thrilled to have this piece on the wonder, mystery, and very long history of #devbiol out in @aeonmag.
aeon.co/essays/after-3000-ye…
Caroline Beck retweeted
Five children who were born deaf can now hear after receiving gene therapy to provide a normal copy of a mutated gene. newscientist.com/article/243…
Caroline Beck retweeted
Our latest: a new optogenetic system for precise spatiotemporal control of gene expression
We use it to dissect the dynamics of Shh gradient formation & patterning
A thread 🧵
biorxiv.org/content/10.1101/…
Researchers found dominant de novo mutations in small ncRNA RNU4-2 could be causative in 0.5% of neurodevelopmental abnormality cases in the UK 100,000 genomes data. With a clinical phenotype of #seizures, short stature #hypotonia and #microcephaly..
Mutations in a small noncoding gene called #RNU4-2 are responsible for one of the most common of the #neurodevelopmental disorders caused by errors in a single gene. #Genetics #Neurodevelopment #IntellectualDisability @GenomicsEngland @SinaiGenetics
nature.com/articles/s41591-0…
...So could this be the most common cause of #DEE as well as the second most common cause of neurodevelopmental delay after MECP2/Rett syndrome? MECP2 is a huge gene, though, and this RNU4-2 is tiny- so it is being hit at a remarkably high rate of mutation..
..This is a fascinating result implicating the splicing variation in brain development and showing the value of publicly available genome databases in pinpointing the causes of #rare disease. Congratulations to all the authors!