We are the research lab of Dr. Steve Crocker at the University of Connecticut School of Medicine. We study demyelinating diseases of the central nervous system.

Farmington, CT
Joined October 2018
CD8+ T cell depletion prevents neuropathology in a mouse model of globoid cell #leukodystrophy, say Pearl Sutter, Stephen Crocker @GlialLab @uconnhealth and colleagues bit.ly/3P9Hqpu #Neuroinflammation
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Role for CD8+ T cells in driving the neuropathology underlying Krabbe’s disease CD8+ T cell depletion prevents neuropathology in a mouse model of globoid cell leukodystrophy rupress.org/jem/article/220/…
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👇@UConn #nation #MS care is a big unmet need in #CT. Join our #MS🚶‍♀️and support research and service programs @mssociety. @MarinaC_Dyb @uconnhealth @UConnResearch @UConnNeurology @UCHI_UConn @UConnWBB @UConnFootball @CTDPH @GlialLab @UconnAging @UConnHartford @TheHartford 💪🧠👏
The @UConn #Nation #MS team is participating in Walk MS®️. Walk MS connects people living with MS and those who care about them. do.nr/v369xs via @DonorDrive Join us @UConnNeurology @UConnWBB @uconnhealth @FellowshipUconn @UConnOUR @UconnAging @UConnNeag @GlialLab
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The abstract submission date to #ISNI Virtual France 2021 is on September 17. Join our invited speakers and be part of our fantastic program. More info on website: isnicongress.org
The Grutzendler lab at Yale has an opening for a postdoctoral fellow to study neuroglial biology in health and neurodegeneration. Required background in molecular/cellular/physiology. Interested individuals please send letter and CV to: [email protected]
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Neural stem cells can transfer mitochondria via extracellular vesicles to target cells both in vitro & in vivo, suggesting a signaling mechanism used by NSCs to modulate physiology & metabolism of target cells @Dr_LPJ @Pluchinolab &co #PLOSBiology plos.io/31WMLGQ
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BREAKING NEWS: The 2020 #NobelPrize in Chemistry has been awarded to Emmanuelle Charpentier and Jennifer A. Doudna “for the development of a method for genome editing.”
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BREAKING NEWS: The 2020 #NobelPrize in Physiology or Medicine has been awarded jointly to Harvey J. Alter, Michael Houghton and Charles M. Rice “for the discovery of Hepatitis C virus.”
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Crocker Lab retweeted
.@SchaferLabUMMS @s_werneburg &co Synapse loss can occur early & prior to other #MultipleSclerosis-relevant pathology & is associated with synapse-localized complement C3. AAV approach to inhibit C3 protects synapses & preserves circuit function authors.elsevier.com/a/1aP20… @GlialLab
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2019 Medicine Laureates William G. Kaelin Jr, Sir Peter J. Ratcliffe and Gregg L. Semenza have identified molecular machinery that regulates the activity of genes in response to varying levels of oxygen. #NobelPrize
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BREAKING NEWS: The 2019 #NobelPrize in Physiology or Medicine has been awarded jointly to William G. Kaelin Jr, Sir Peter J. Ratcliffe and Gregg L. Semenza “for their discoveries of how cells sense and adapt to oxygen availability.”
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Check the latest paper from our lab in collaboration with @GlialLab and @TKDeeny examining how TIMP-1 reduces the development of inflammatory pain. frontiersin.org/article/10.3…
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Niche stiffness underlies the ageing of central nervous system progenitor cells - important new research from Institute PIs Robin Franklin and @KevinChalut published in @Nature nature.com/articles/s41586-0…
Congratulations Maryna, David and the lab on the @pnas publication! This started out as a fun summer project in which we asked if vital dyes labeled CNS lesions in vivo. Tracking the evolution of CNS remyelinating lesion in mice with neutral red dye pnas.org/content/early/2019/…
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A new culprit for multiple sclerosis relapses The research also shows a new way to study multiple sclerosis (MS) in mice that is closer to the human form of the disease. #neurology #multiplesclerosis #health neurosciencenews.com/cd8-rrm…
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Society-led study just released: There are twice as many people living with MS in the US than previously thought. “I am glad to know that MS is a focus and that there is a push to get accurate numbers. The larger the number of people to study, the better we can figure out ...
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Crocker Lab retweeted
To the robot who turned 90 days into 15 years of exploration: You were, and are, the Opportunity of a lifetime. Rest well, rover. Your mission is complete. (2004-2019) mars.nasa.gov #ThanksOppy
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Working WITH not FOR is the proper language to describe relationship between PIs and their trainees! – at Charlotte, NC
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