@Gould_Lab

We study the coordination & execution of cell ➗ division using 🧬 genetics, 🦠 cell biology, 🔬microscopy, proteomics & more in #Pombe! Tweets from lab members.

 Nashville, TN
medschool.vanderbilt.edu/gould-lab/
Joined November 2017
  • Tweets263
  • Following380
  • Followers720
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Alaina Willet, Kathleen Gould and team @Gould_Lab find that Duc1 influences plasma membrane lipid composition and cytokinetic ring anchoring. #OpenAccess Highlight: journals.biologists.com/jcs/… Article: journals.biologists.com/jcs/…
Live-cell imaging of Duc1–mNG and mCherry–AHDL in wild-type or scs2Δ scs22Δ cells showing Duc1 is excluded from the cell division site

ALT Live-cell imaging of Duc1–mNG and mCherry–AHDL in wild-type or scs2Δ scs22Δ cells showing Duc1 is excluded from the cell division site

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From MBoC @Gould_Lab report that the FHA domain in one SIP component is necessary & sufficient for SIP spindle pole body (SPB) targeting & function. Cell viability requires SPB SIP localization is transient. Residues unique to its catalytic subunit... doi.org/10.1091/mbc.E24-04-0…
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From MBoC The core spindle pole body scaffold Ppc89 links the pericentrin ortholog Pcp1 to the fission yeast spindle pole body via an evolutionarily conserved interface @Gould_Lab doi.org/10.1091/mbc.E24-05-0…
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send your awesome #cleavage stories to @ASCBiology #cellbio2024 for our 8th biannual Cytokinesis subgroup! (stable actomyosin rings and network reconstitution work welcome too!) please RT for all those last-minute #cell #Biology -ists out there burning the midnight arc lamp!
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Once again we organize the 8th Frontiers in Cytokinesis subgroup at #CellBio2024 in San Diego. The deadline to submit an abstract to be considered for a talk is August 6. Cytokinesis folks, please consider presenting!
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In the lab. 8 am Sunday to see the outcome of a genetic screen in S japonicus, made popular by ⁦@alebenoit⁩ Reminds me of the time in ⁦@Gould_Lab⁩ Lab meeting tomorrow and want to present my work.
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Please feel free to retweet I have a post-doctoral position to measure cytokinetic forces in collaboration with Justin Molloy in Warwick. warwick-careers.tal.net/vx/l…
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Characterization of temperature-sensitive alleles of Schizosaccharomyces pombe septation initiation network components #micropublication #biology #data #caltechlibrary #Spombe #PhenotypeData #GeneticScreens #NewFinding #MaterialsAndReagents micropublication.org/journal…
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The program of the Plant and Microbial Cytoskeleton GRC is online: grc.org/plant-and-microbial-… Lots of opportunities for short talks! Re-tweet and submit your abstracts! #cytoskeleton #actin #microtubules #septins #yeast #plants #bacteria #archaea #protists
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Another set of temperature sensitive alleles that didn’t fit into a recent pub. Special thanks to undergraduate student Bita Tavafoghi for her hard work finishing this up!
microPublication@Micropub7n2 Apr 2024
Generation and characterization of temperature-sensitive alleles encoding GPI anchored proteins Psu1 and Dfg502 in Schizosaccharomyces pombe #micropublication #biology #data #caltechlibrary #Spombe #PhenotypeData #FindingsPreviouslyNotShown micropublication.org/journal…
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FEATURED MBoC ASSOCIATE EDITOR: @SophieMartinLab, @unil How do you believe MBoC can benefit researchers in your area? MBoC has been a place to publish no-hype, solid research in cell biology & will continue to be thanks to strong community engagement. molbiolcell.org/
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To all lovers of the #cytoskeleton: periodic reminder to register for the Plant and Microbial Cytoskeleton GRC and GRS 2024 Great line-up of speakers! Check the website to register: grc.org/plant-and-microbial-… Please RT!
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Join us today at 12:15 pm in 1220 MRB III @VanderbiltCDB, @fredchanglab @Gould_Lab @VUBasicSciences
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Replying to @AlainaWillet
@AlainaWillet, Kathleen Gould @Gould_Lab and colleagues @VanderbiltCDB find that Pik1 localises exclusively to the trans-Golgi in fission yeast, where it contributes to PI4P but not PI(4,5)P2 synthesis and does not affect cytokinesis. journals.biologists.com/jcs/…
Live-cell images showing that the PI4P sensor GFP-P4CSicC colocalises with the trans-Golgi marker Sec72.

ALT Live-cell images showing that the PI4P sensor GFP-P4CSicC colocalises with the trans-Golgi marker Sec72.

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Characterization of Pik1 function in fission yeast reveals its conserved role in lipid synthesis and not cytokinesis. Journal of Cell Science. journals.biologists.com/jcs/… @Gould_Lab @AlainaWillet
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New work from Alaina H. Willet et al. at Vanderbilt University School of Medicine (@VUmedicine) shows that Ankyrin-1 inhibits #membrane binding of Myosin-1, an actin-based motor that works with the Arp2/3 complex to trigger #endocytosis in yeast. molbiolcell.org/doi/epdf/10.…
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Revised fission yeast nomenclature for genes and alleles now published in @GeneticsGSA . We provide new standards for ncRNA genes and for allele descriptions to enable machine readability. Thanks to @manu_lera for driving this to completion. @news4go @uniprot @CamBiochem
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#NovelGeneCharacterization of a conserved #UnknownProtein Countdown:625 #FissionYeast #UnknownProteins A new regulator of endocytic myosin-1 membrane binding that is conserved from yeast to humans
Gould Lab@Gould_Lab3 Aug 2023
Our newest publication in now online @MBoCjournal headed by @AlainaWillet ! We found a new regulator of endocytic myosin-1 membrane binding that is conserved from yeast to humans. doi.org/10.1091/mbc.E23-06-0…
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Published in @MBoCjournal on 02/08, curated by @AlainaWillet @Gould_Lab on 09/08, updated in @PomBase on 11/08 - did @AlainaWillet just break her #CommunityCuration the "From publication to @Pombase" record?
S. pombe model organism knowledgebase@PomBase11 Aug 2023
#NovelGeneCharacterization of a conserved #UnknownProtein Countdown:625 #FissionYeast #UnknownProteins A new regulator of endocytic myosin-1 membrane binding that is conserved from yeast to humans
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I’m so very excited that the Cullati lab will be opening September 2023 @WWUChem! I’m like the dog that caught the car - I get to teach undergrad biochem, mentor students, and keep learning about kinase signaling in beautiful Bellingham WA ❤️🤩🎉
Sierra standing by a sculpture in front of the Chemistry building, presenting the building like Vanna White

ALT Sierra standing by a sculpture in front of the Chemistry building, presenting the building like Vanna White

A selfie of Sierra in front of a WWU Chem sign. The letters are written like elements on the periodic table.

ALT A selfie of Sierra in front of a WWU Chem sign. The letters are written like elements on the periodic table.

Sierra standing in front of a campus building with a curved path and green trees and flowers.

ALT Sierra standing in front of a campus building with a curved path and green trees and flowers.

Selfie of Sierra and Erik with Bellingham Bay in the background

ALT Selfie of Sierra and Erik with Bellingham Bay in the background

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