Conditions complicated by gout are: polycythemia, lead poisoning, renal failure, hemolytic anemia, psoriasis, and solid organ transplants.
#Gout in 75% of cases can come with the metabolic syndrome, abdominal obesity, hypertension, insulin resistance, and abnormal lipid levels.
The occurrence of gout is partly genetic, contributing to about 60% of variability in uric acid level.
The consumption of coffee, vitamin C, and dairy products, as well as physical fitness, appear to decrease the risk of gout.
Dietary causes of gout account for about 12% of gout. These include alcohol, fructose-sweetened drinks, meat, and seafood.
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About 10% of people with #hyperuricemia develop #gout at some point in their lifetimes.
Underexcretion of #uricacid by the kidney is the primary cause of #hyperuricemia in about 90% of cases; overproduction is in less than 10%.
Rarely fatigue and high fever may occur along with the #gout joint pain.
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The reason for #gout onset at night is due to the lower body temperature then.
#Gout joint pain usually begins over 2-4 hours and during the night.
#Gout can affect other joints, such as the heels, knees, wrists, and fingers.
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#Gout was historically known as "the disease of kings" or "rich man's disease."
The increase of gout in past decades is believed to be due to metabolic syndrome, longer life expectancy, and changes in diet.
#Gout has become more common in recent decades, affecting about 1-2% of the Western population at some point in their lives.
